Towards a dry separation method of radioscandium from bulk amounts of titanium.
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| Title: | Towards a dry separation method of radioscandium from bulk amounts of titanium. |
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| Authors: | Chai, Xiuyun1 (AUTHOR) xiuyun.chai@unibe.ch, Nawar, Mohamed F.1 (AUTHOR), Lüthi, Matthias1,2 (AUTHOR), Zingg, Ronald1 (AUTHOR), Kottler, Christian2 (AUTHOR), Türler, Andreas1 (AUTHOR) |
| Source: | Journal of Radioanalytical & Nuclear Chemistry. May2025, Vol. 334 Issue 5, p3359-3366. 8p. |
| Subjects: | Monte Carlo method, Methods engineering, Nuclear medicine, Titanium, Scandium |
| Abstract: | True theranostic radionuclide pairs are gaining interest in nuclear medicine. However, their application is limited due to their reduced availability. 47Sc is a promising therapeutic partner to the diagnostic 43Sc and 44Sc due to its ideal half-life and beta energy. This study attempted to develop a dry, gas–solid phase separation of non-carrier-added radioscandium from macro amounts of titanium. The results showed a 99.9% release of 47Sc from Ti foil of 50 μm thickness at 1100 °C in vacuum. Furthermore, a Monte Carlo model was developed to describe the release of Sc from Ti as a function of temperature and foil thickness. With this model the desorption energy of Sc from Ti surfaces was determined to be 390 ± 5 kJ/mol in excellent agreement with theoretical predictions. In an attempt to recover the evaporated 47Sc on a cold finger, highest overall yields of 65% were observed for gold surfaces. For other catcher materials such as Ti, Ta, and brass significantly lower overall yields between 27 and 47% were determined. Furthermore, it was not possible to quantitatively remove the 47Sc from the Au catcher, even when washing with concentrated acids. Attempts to increase the release of scandium from thick, sintered Ti samples failed to show an improvement over solid titanium. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Radioanalytical & Nuclear Chemistry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 185725207 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Towards a dry separation method of radioscandium from bulk amounts of titanium. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Chai%2C+Xiuyun%22">Chai, Xiuyun</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> xiuyun.chai@unibe.ch</i><br /><searchLink fieldCode="AR" term="%22Nawar%2C+Mohamed+F%2E%22">Nawar, Mohamed F.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lüthi%2C+Matthias%22">Lüthi, Matthias</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zingg%2C+Ronald%22">Zingg, Ronald</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kottler%2C+Christian%22">Kottler, Christian</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Türler%2C+Andreas%22">Türler, Andreas</searchLink><relatesTo>1</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Radioanalytical+%26+Nuclear+Chemistry%22">Journal of Radioanalytical & Nuclear Chemistry</searchLink>. May2025, Vol. 334 Issue 5, p3359-3366. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Monte+Carlo+method%22">Monte Carlo method</searchLink><br /><searchLink fieldCode="DE" term="%22Methods+engineering%22">Methods engineering</searchLink><br /><searchLink fieldCode="DE" term="%22Nuclear+medicine%22">Nuclear medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Titanium%22">Titanium</searchLink><br /><searchLink fieldCode="DE" term="%22Scandium%22">Scandium</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: True theranostic radionuclide pairs are gaining interest in nuclear medicine. However, their application is limited due to their reduced availability. 47Sc is a promising therapeutic partner to the diagnostic 43Sc and 44Sc due to its ideal half-life and beta energy. This study attempted to develop a dry, gas–solid phase separation of non-carrier-added radioscandium from macro amounts of titanium. The results showed a 99.9% release of 47Sc from Ti foil of 50 μm thickness at 1100 °C in vacuum. Furthermore, a Monte Carlo model was developed to describe the release of Sc from Ti as a function of temperature and foil thickness. With this model the desorption energy of Sc from Ti surfaces was determined to be 390 ± 5 kJ/mol in excellent agreement with theoretical predictions. In an attempt to recover the evaporated 47Sc on a cold finger, highest overall yields of 65% were observed for gold surfaces. For other catcher materials such as Ti, Ta, and brass significantly lower overall yields between 27 and 47% were determined. Furthermore, it was not possible to quantitatively remove the 47Sc from the Au catcher, even when washing with concentrated acids. Attempts to increase the release of scandium from thick, sintered Ti samples failed to show an improvement over solid titanium. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Radioanalytical & Nuclear Chemistry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10967-025-10092-4 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 3359 Subjects: – SubjectFull: Monte Carlo method Type: general – SubjectFull: Methods engineering Type: general – SubjectFull: Nuclear medicine Type: general – SubjectFull: Titanium Type: general – SubjectFull: Scandium Type: general Titles: – TitleFull: Towards a dry separation method of radioscandium from bulk amounts of titanium. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chai, Xiuyun – PersonEntity: Name: NameFull: Nawar, Mohamed F. – PersonEntity: Name: NameFull: Lüthi, Matthias – PersonEntity: Name: NameFull: Zingg, Ronald – PersonEntity: Name: NameFull: Kottler, Christian – PersonEntity: Name: NameFull: Türler, Andreas IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 02365731 Numbering: – Type: volume Value: 334 – Type: issue Value: 5 Titles: – TitleFull: Journal of Radioanalytical & Nuclear Chemistry Type: main |
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