View in EDS HTML Full Text PDF Full Text

P(LMA-co-tBMA-co-MAA) Copolymers Bearing Amphiphilic and Polyelectrolyte Characteristics: Synthetic Aspects and Properties in Aqueous Solutions.

Saved in:
Bibliographic Details
Title: P(LMA-co-tBMA-co-MAA) Copolymers Bearing Amphiphilic and Polyelectrolyte Characteristics: Synthetic Aspects and Properties in Aqueous Solutions.
Authors: Balafouti, Anastasia1,2 (AUTHOR), Pispas, Stergios1,2 (AUTHOR) pispas@eie.gr
Source: Polymers (20734360). Jun2025, Vol. 17 Issue 11, p1473. 18p.
Subjects: Proton magnetic resonance, Random copolymers, Gel permeation chromatography, Nuclear magnetic resonance, Biomedical materials, Attenuated total reflectance
Abstract: In this study, we explore the design of novel random poly(lauryl methacrylate-co-tert-butyl methacrylate-co-methacrylic acid), P(LMA-co-tBMA-co-MAA) copolymers via the RAFT copolymerization of LMA and tBMA followed by the selective hydrolysis of tBMA segments. For the molecular characterization of the novel copolymer, a series of physicochemical techniques were implemented, including size exclusion chromatography (SEC), proton nuclear magnetic resonance (1H-NMR) and attenuated total reflectance–Fourier transform infrared (ATR–FTIR) spectroscopy. Our experimental results confirmed the successful synthesis of the targeted copolymers. The compositions were in accordance with the targeted differing fraction of hydrophobic tBMA/LMA elements, and hydrolysis resulted in at least 64% conversion to hydrophilic MAA units. The copolymers, bearing both an amphiphilic character and polyelectrolyte properties while being composed of randomly distributed monomeric segments of biocompatible materials, were subsequently investigated in terms of their self-assembly behavior in aqueous solutions. Dynamic light scattering and fluorescence spectroscopy experiments demonstrated the formation of self-assembled nanoaggregates (average hydrodynamic radii, Rh < 100 nm) that formed spontaneously, having low critical aggregation concentration (CAC) values (below 3.5 × 10−6 g/mL), and highlighted the feasibility of using these copolymer systems as nanocarriers for biomedical applications. [ABSTRACT FROM AUTHOR]
Copyright of Polymers (20734360) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: egs
DbLabel: Engineering Source
An: 185866779
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: P(LMA-co-tBMA-co-MAA) Copolymers Bearing Amphiphilic and Polyelectrolyte Characteristics: Synthetic Aspects and Properties in Aqueous Solutions.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Balafouti%2C+Anastasia%22&quot;&gt;Balafouti, Anastasia&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Pispas%2C+Stergios%22&quot;&gt;Pispas, Stergios&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt; (AUTHOR)&lt;i&gt; pispas@eie.gr&lt;/i&gt;
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Polymers+%2820734360%29%22&quot;&gt;Polymers (20734360)&lt;/searchLink&gt;. Jun2025, Vol. 17 Issue 11, p1473. 18p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Proton+magnetic+resonance%22&quot;&gt;Proton magnetic resonance&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Random+copolymers%22&quot;&gt;Random copolymers&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Gel+permeation+chromatography%22&quot;&gt;Gel permeation chromatography&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Nuclear+magnetic+resonance%22&quot;&gt;Nuclear magnetic resonance&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Biomedical+materials%22&quot;&gt;Biomedical materials&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Attenuated+total+reflectance%22&quot;&gt;Attenuated total reflectance&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: In this study, we explore the design of novel random poly(lauryl methacrylate-co-tert-butyl methacrylate-co-methacrylic acid), P(LMA-co-tBMA-co-MAA) copolymers via the RAFT copolymerization of LMA and tBMA followed by the selective hydrolysis of tBMA segments. For the molecular characterization of the novel copolymer, a series of physicochemical techniques were implemented, including size exclusion chromatography (SEC), proton nuclear magnetic resonance (1H-NMR) and attenuated total reflectance–Fourier transform infrared (ATR–FTIR) spectroscopy. Our experimental results confirmed the successful synthesis of the targeted copolymers. The compositions were in accordance with the targeted differing fraction of hydrophobic tBMA/LMA elements, and hydrolysis resulted in at least 64% conversion to hydrophilic MAA units. The copolymers, bearing both an amphiphilic character and polyelectrolyte properties while being composed of randomly distributed monomeric segments of biocompatible materials, were subsequently investigated in terms of their self-assembly behavior in aqueous solutions. Dynamic light scattering and fluorescence spectroscopy experiments demonstrated the formation of self-assembled nanoaggregates (average hydrodynamic radii, Rh &lt; 100 nm) that formed spontaneously, having low critical aggregation concentration (CAC) values (below 3.5 &#215; 10−6 g/mL), and highlighted the feasibility of using these copolymer systems as nanocarriers for biomedical applications. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of Polymers (20734360) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=185866779
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3390/polym17111473
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 18
        StartPage: 1473
    Subjects:
      – SubjectFull: Proton magnetic resonance
        Type: general
      – SubjectFull: Random copolymers
        Type: general
      – SubjectFull: Gel permeation chromatography
        Type: general
      – SubjectFull: Nuclear magnetic resonance
        Type: general
      – SubjectFull: Biomedical materials
        Type: general
      – SubjectFull: Attenuated total reflectance
        Type: general
    Titles:
      – TitleFull: P(LMA-co-tBMA-co-MAA) Copolymers Bearing Amphiphilic and Polyelectrolyte Characteristics: Synthetic Aspects and Properties in Aqueous Solutions.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Balafouti, Anastasia
      – PersonEntity:
          Name:
            NameFull: Pispas, Stergios
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: Jun2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 20734360
          Numbering:
            – Type: volume
              Value: 17
            – Type: issue
              Value: 11
          Titles:
            – TitleFull: Polymers (20734360)
              Type: main
ResultId 1