Comparative Structural and Mechanical Characterization of FDM 3D‐Printed PLA Scaffolds for Bone Tissue Engineering Applications.
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| Title: | Comparative Structural and Mechanical Characterization of FDM 3D‐Printed PLA Scaffolds for Bone Tissue Engineering Applications. |
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| Authors: | Adel, Abdellattief1 (AUTHOR) abdellattief.adel@eng.suezuni.edu.eg, Adly, Mahmoud A.2 (AUTHOR), Reda, Reham1 (AUTHOR), Abdelkawy, Abdallah2 (AUTHOR) |
| Source: | Polymers for Advanced Technologies. Jul2025, Vol. 36 Issue 7, p1-19. 19p. |
| Subjects: | Tissue scaffolds, Unit cell, Porosity, Fused deposition modeling, Mechanical behavior of materials, Biomimetic materials, Tissue engineering |
| Abstract: | Cellular scaffolds can provide morphological and mechanical integrity with human bone. Various structural designs have been studied; however, their structural and mechanical properties have not been sufficiently compared under the same conditions. This study investigates the effect of unit cell type and size on the dimensional accuracy, porosity accuracy, pore size, and compressive properties of cellular polylactic acid (PLA) scaffolds. These scaffolds were additively manufactured using the fused deposition modeling (FDM) method. Three levels of unit cell type and unit cell sizes were investigated. Strut‐based cubic, octet, and surface‐based gyroid structures with 2.5, 3, and 4 mm unit cell sizes were designed, fabricated, and characterized. The scaffolds were created with a constant porosity of 60%. A two‐way analysis of variance (ANOVA) was performed to identify the significance of unit cell type and size on the measured characteristics. Unit cell type and size significantly impact structural and mechanical properties, as well as the printability of the scaffolds. The structures exhibit trabecular bone‐like mechanical properties, with deformation behavior more dependent on unit cell type than unit cell size. Results show preferability to gyroid structures, with recommendations for enhancing their porosity accuracy. [ABSTRACT FROM AUTHOR] |
| Copyright of Polymers for Advanced Technologies is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 186996912 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Comparative Structural and Mechanical Characterization of FDM 3D‐Printed PLA Scaffolds for Bone Tissue Engineering Applications. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Adel%2C+Abdellattief%22">Adel, Abdellattief</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> abdellattief.adel@eng.suezuni.edu.eg</i><br /><searchLink fieldCode="AR" term="%22Adly%2C+Mahmoud+A%2E%22">Adly, Mahmoud A.</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Reda%2C+Reham%22">Reda, Reham</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Abdelkawy%2C+Abdallah%22">Abdelkawy, Abdallah</searchLink><relatesTo>2</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Polymers+for+Advanced+Technologies%22">Polymers for Advanced Technologies</searchLink>. Jul2025, Vol. 36 Issue 7, p1-19. 19p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Tissue+scaffolds%22">Tissue scaffolds</searchLink><br /><searchLink fieldCode="DE" term="%22Unit+cell%22">Unit cell</searchLink><br /><searchLink fieldCode="DE" term="%22Porosity%22">Porosity</searchLink><br /><searchLink fieldCode="DE" term="%22Fused+deposition+modeling%22">Fused deposition modeling</searchLink><br /><searchLink fieldCode="DE" term="%22Mechanical+behavior+of+materials%22">Mechanical behavior of materials</searchLink><br /><searchLink fieldCode="DE" term="%22Biomimetic+materials%22">Biomimetic materials</searchLink><br /><searchLink fieldCode="DE" term="%22Tissue+engineering%22">Tissue engineering</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Cellular scaffolds can provide morphological and mechanical integrity with human bone. Various structural designs have been studied; however, their structural and mechanical properties have not been sufficiently compared under the same conditions. This study investigates the effect of unit cell type and size on the dimensional accuracy, porosity accuracy, pore size, and compressive properties of cellular polylactic acid (PLA) scaffolds. These scaffolds were additively manufactured using the fused deposition modeling (FDM) method. Three levels of unit cell type and unit cell sizes were investigated. Strut‐based cubic, octet, and surface‐based gyroid structures with 2.5, 3, and 4 mm unit cell sizes were designed, fabricated, and characterized. The scaffolds were created with a constant porosity of 60%. A two‐way analysis of variance (ANOVA) was performed to identify the significance of unit cell type and size on the measured characteristics. Unit cell type and size significantly impact structural and mechanical properties, as well as the printability of the scaffolds. The structures exhibit trabecular bone‐like mechanical properties, with deformation behavior more dependent on unit cell type than unit cell size. Results show preferability to gyroid structures, with recommendations for enhancing their porosity accuracy. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Polymers for Advanced Technologies is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/pat.70257 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 19 StartPage: 1 Subjects: – SubjectFull: Tissue scaffolds Type: general – SubjectFull: Unit cell Type: general – SubjectFull: Porosity Type: general – SubjectFull: Fused deposition modeling Type: general – SubjectFull: Mechanical behavior of materials Type: general – SubjectFull: Biomimetic materials Type: general – SubjectFull: Tissue engineering Type: general Titles: – TitleFull: Comparative Structural and Mechanical Characterization of FDM 3D‐Printed PLA Scaffolds for Bone Tissue Engineering Applications. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Adel, Abdellattief – PersonEntity: Name: NameFull: Adly, Mahmoud A. – PersonEntity: Name: NameFull: Reda, Reham – PersonEntity: Name: NameFull: Abdelkawy, Abdallah IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: Jul2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 10427147 Numbering: – Type: volume Value: 36 – Type: issue Value: 7 Titles: – TitleFull: Polymers for Advanced Technologies Type: main |
| ResultId | 1 |
