View in EDS HTML Full Text PDF Full Text

Crown Ether-Functionalized Polyethersulfone Membranes with Potential Applications in Hemodialysis.

Saved in:
Bibliographic Details
Title: Crown Ether-Functionalized Polyethersulfone Membranes with Potential Applications in Hemodialysis.
Authors: Oprea, Madalina1,2 (AUTHOR), Pandele, Andreea Madalina1,2 (AUTHOR), Enachescu, Catalin Ionel3 (AUTHOR), Antoniac, Iulian Vasile4,5 (AUTHOR) anca.fratila@ulbsibiu.ro, Voicu, Stefan Ioan1,2,5 (AUTHOR) iulian.antoniac@upb.ro, Fratila, Anca Maria6,7 (AUTHOR)
Source: Polymers (20734360). Aug2025, Vol. 17 Issue 16, p2184. 20p.
Subjects: Crown ethers, Polyethersulfone, Functional groups, Hemodialysis, Biological membranes, Plasma materials processing, Biocompatibility
Abstract: Polyethersulfone (PES) is one of the most used synthetic polymers for the production of hemodialysis membranes, due to its appropriate features, such as biocompatibility, high permeability for low-molecular-weight proteins, high endotoxin retention ability, and resistance to sterilization processes. However, there is room for improvement regarding their anticoagulant properties when coming into contact with blood. In the present study, commercial PES membranes were plasma-treated and then chemically modified with crown ether, an organic compound that could interfere with the coagulation cascade by complexating Ca2+ in the blood. The physico-chemical and morphological characteristics of the membranes were determined by FT-IR, XPS, TGA, SEM, and CT analyses, while their efficiency in retaining calcium ions was evaluated via ICP-MS. The results revealed that plasma treatment with a mixture of argon and ammonia was the most effective in generating nitrogen-containing surface functional groups and that these moieties can be successfully used for the covalent functionalization of the membranes. Also, the Ca2+ retention ability of the PES membranes was improved by up to 30% after chemical modification with 4′-aminobenzo-15-crown-5 ether. [ABSTRACT FROM AUTHOR]
Copyright of Polymers (20734360) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: egs
DbLabel: Engineering Source
An: 187612683
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Crown Ether-Functionalized Polyethersulfone Membranes with Potential Applications in Hemodialysis.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Oprea%2C+Madalina%22">Oprea, Madalina</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pandele%2C+Andreea+Madalina%22">Pandele, Andreea Madalina</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Enachescu%2C+Catalin+Ionel%22">Enachescu, Catalin Ionel</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Antoniac%2C+Iulian+Vasile%22">Antoniac, Iulian Vasile</searchLink><relatesTo>4,5</relatesTo> (AUTHOR)<i> anca.fratila@ulbsibiu.ro</i><br /><searchLink fieldCode="AR" term="%22Voicu%2C+Stefan+Ioan%22">Voicu, Stefan Ioan</searchLink><relatesTo>1,2,5</relatesTo> (AUTHOR)<i> iulian.antoniac@upb.ro</i><br /><searchLink fieldCode="AR" term="%22Fratila%2C+Anca+Maria%22">Fratila, Anca Maria</searchLink><relatesTo>6,7</relatesTo> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Polymers+%2820734360%29%22">Polymers (20734360)</searchLink>. Aug2025, Vol. 17 Issue 16, p2184. 20p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Crown+ethers%22">Crown ethers</searchLink><br /><searchLink fieldCode="DE" term="%22Polyethersulfone%22">Polyethersulfone</searchLink><br /><searchLink fieldCode="DE" term="%22Functional+groups%22">Functional groups</searchLink><br /><searchLink fieldCode="DE" term="%22Hemodialysis%22">Hemodialysis</searchLink><br /><searchLink fieldCode="DE" term="%22Biological+membranes%22">Biological membranes</searchLink><br /><searchLink fieldCode="DE" term="%22Plasma+materials+processing%22">Plasma materials processing</searchLink><br /><searchLink fieldCode="DE" term="%22Biocompatibility%22">Biocompatibility</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Polyethersulfone (PES) is one of the most used synthetic polymers for the production of hemodialysis membranes, due to its appropriate features, such as biocompatibility, high permeability for low-molecular-weight proteins, high endotoxin retention ability, and resistance to sterilization processes. However, there is room for improvement regarding their anticoagulant properties when coming into contact with blood. In the present study, commercial PES membranes were plasma-treated and then chemically modified with crown ether, an organic compound that could interfere with the coagulation cascade by complexating Ca2+ in the blood. The physico-chemical and morphological characteristics of the membranes were determined by FT-IR, XPS, TGA, SEM, and CT analyses, while their efficiency in retaining calcium ions was evaluated via ICP-MS. The results revealed that plasma treatment with a mixture of argon and ammonia was the most effective in generating nitrogen-containing surface functional groups and that these moieties can be successfully used for the covalent functionalization of the membranes. Also, the Ca2+ retention ability of the PES membranes was improved by up to 30% after chemical modification with 4′-aminobenzo-15-crown-5 ether. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Polymers (20734360) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=187612683
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3390/polym17162184
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 20
        StartPage: 2184
    Subjects:
      – SubjectFull: Crown ethers
        Type: general
      – SubjectFull: Polyethersulfone
        Type: general
      – SubjectFull: Functional groups
        Type: general
      – SubjectFull: Hemodialysis
        Type: general
      – SubjectFull: Biological membranes
        Type: general
      – SubjectFull: Plasma materials processing
        Type: general
      – SubjectFull: Biocompatibility
        Type: general
    Titles:
      – TitleFull: Crown Ether-Functionalized Polyethersulfone Membranes with Potential Applications in Hemodialysis.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Oprea, Madalina
      – PersonEntity:
          Name:
            NameFull: Pandele, Andreea Madalina
      – PersonEntity:
          Name:
            NameFull: Enachescu, Catalin Ionel
      – PersonEntity:
          Name:
            NameFull: Antoniac, Iulian Vasile
      – PersonEntity:
          Name:
            NameFull: Voicu, Stefan Ioan
      – PersonEntity:
          Name:
            NameFull: Fratila, Anca Maria
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 08
              Text: Aug2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 20734360
          Numbering:
            – Type: volume
              Value: 17
            – Type: issue
              Value: 16
          Titles:
            – TitleFull: Polymers (20734360)
              Type: main
ResultId 1