Homologous nanocellulose modification: A "like cures like" strategy against coffee-ring and infiltration effects in paper-based colorimetric detection.
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| Title: | Homologous nanocellulose modification: A "like cures like" strategy against coffee-ring and infiltration effects in paper-based colorimetric detection. |
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| Authors: | Sun, Linan1 (AUTHOR), Lou, Yafei1 (AUTHOR), Chen, Siyu1 (AUTHOR), Weng, Hongyue1 (AUTHOR), Li, Jiahao1 (AUTHOR), Lin, Zhihui2 (AUTHOR), Tian, Junfei1,3 (AUTHOR) jftian_scut@163.com, Cao, Rong1,4 (AUTHOR) caorong_chem@163.com |
| Source: | Analytica Chimica Acta. Nov2025, Vol. 1373, pN.PAG-N.PAG. 1p. |
| Subjects: | Cellulose, Cellulose nanocrystals, Colorimetric analysis, Soil infiltration, Statistical accuracy, Sensitivity & specificity (Statistics), Nanosensors, Capillary flow |
| Abstract: | While paper-based colorimetric assays have seen significant progress in recent years, persistent challenges including the coffee-ring effect and infiltration effect continue to affect the color uniformity of detection results, leading to decreased sensitivity and accuracy of the detection. Recent advancements in suppressing these two effects mainly depend on chemical modification of cellulose fibers or application of specific functional coatings. However, the former's complex procedures impede large-scale implementation, while the latter's non-cellulosic additives risk unpredictable interactions with analytes or interference in colorimetric reactions. Herein, we propose a "like cures like" strategy by modifying cellulose-based paper substrates with nanocellulose materials, that is, cellulose nanofibers (CNFs) and cellulose nanocrystals (CNCs). This approach aims to suppress the capillary flow of the liquid sample and prevent penetration of chromogenic products within the paper substrate. Systematic characterization of the modified paper substrates focused on key aspects including fluid transport capacity and chromogenic performance of the resulting sensors. The optimized modified substrates were tested for detecting Ni2+ using dimethylglyoxime and Fe2+ using bathophenanthroline. The distribution of their colorimetric products in the paper substrates demonstrated effective suppression of both the coffee-ring and infiltration effects. Compared to untreated counterparts, the CNCs-treated paper sensors exhibited enhanced detection accuracy and sensitivity. The linear correlation coefficients were 0.99 for Ni2+ and Fe2+ detection, with limits of detection of 0.4520 ppm for Ni2+ and 0.1564 ppm for Fe2+, respectively. This study presents a novel strategy for constructing paper-based colorimetric sensors by in situ formation of micro-nano composite structures via nanocellulose modification. By leveraging the shared cellulose origin between the substrate and the modifier, this approach eliminates the need for foreign additives and enhances the colorimetric performance through improved uniformity and signal intensity. Consequently, this method enhances the accuracy and sensitivity of paper-based colorimetric detection while avoiding potential interferences from non-cellulosic additives. [Display omitted] • Homologous nanocellulose-treated paper hinders coffee-ring and infiltration effects. • CNCs surpass CNFs in preserving paper's structure and fluid transport properties. • CNCs-treated paper sensor improves colorimetric performance in Ni2+/Fe2+ detection. [ABSTRACT FROM AUTHOR] |
| Copyright of Analytica Chimica Acta is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 187790823 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Homologous nanocellulose modification: A "like cures like" strategy against coffee-ring and infiltration effects in paper-based colorimetric detection. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sun%2C+Linan%22">Sun, Linan</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lou%2C+Yafei%22">Lou, Yafei</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Siyu%22">Chen, Siyu</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Weng%2C+Hongyue%22">Weng, Hongyue</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Li%2C+Jiahao%22">Li, Jiahao</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lin%2C+Zhihui%22">Lin, Zhihui</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tian%2C+Junfei%22">Tian, Junfei</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<i> jftian_scut@163.com</i><br /><searchLink fieldCode="AR" term="%22Cao%2C+Rong%22">Cao, Rong</searchLink><relatesTo>1,4</relatesTo> (AUTHOR)<i> caorong_chem@163.com</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Analytica+Chimica+Acta%22">Analytica Chimica Acta</searchLink>. Nov2025, Vol. 1373, pN.PAG-N.PAG. 1p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Cellulose%22">Cellulose</searchLink><br /><searchLink fieldCode="DE" term="%22Cellulose+nanocrystals%22">Cellulose nanocrystals</searchLink><br /><searchLink fieldCode="DE" term="%22Colorimetric+analysis%22">Colorimetric analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Soil+infiltration%22">Soil infiltration</searchLink><br /><searchLink fieldCode="DE" term="%22Statistical+accuracy%22">Statistical accuracy</searchLink><br /><searchLink fieldCode="DE" term="%22Sensitivity+%26+specificity+%28Statistics%29%22">Sensitivity & specificity (Statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22Nanosensors%22">Nanosensors</searchLink><br /><searchLink fieldCode="DE" term="%22Capillary+flow%22">Capillary flow</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: While paper-based colorimetric assays have seen significant progress in recent years, persistent challenges including the coffee-ring effect and infiltration effect continue to affect the color uniformity of detection results, leading to decreased sensitivity and accuracy of the detection. Recent advancements in suppressing these two effects mainly depend on chemical modification of cellulose fibers or application of specific functional coatings. However, the former's complex procedures impede large-scale implementation, while the latter's non-cellulosic additives risk unpredictable interactions with analytes or interference in colorimetric reactions. Herein, we propose a "like cures like" strategy by modifying cellulose-based paper substrates with nanocellulose materials, that is, cellulose nanofibers (CNFs) and cellulose nanocrystals (CNCs). This approach aims to suppress the capillary flow of the liquid sample and prevent penetration of chromogenic products within the paper substrate. Systematic characterization of the modified paper substrates focused on key aspects including fluid transport capacity and chromogenic performance of the resulting sensors. The optimized modified substrates were tested for detecting Ni2+ using dimethylglyoxime and Fe2+ using bathophenanthroline. The distribution of their colorimetric products in the paper substrates demonstrated effective suppression of both the coffee-ring and infiltration effects. Compared to untreated counterparts, the CNCs-treated paper sensors exhibited enhanced detection accuracy and sensitivity. The linear correlation coefficients were 0.99 for Ni2+ and Fe2+ detection, with limits of detection of 0.4520 ppm for Ni2+ and 0.1564 ppm for Fe2+, respectively. This study presents a novel strategy for constructing paper-based colorimetric sensors by in situ formation of micro-nano composite structures via nanocellulose modification. By leveraging the shared cellulose origin between the substrate and the modifier, this approach eliminates the need for foreign additives and enhances the colorimetric performance through improved uniformity and signal intensity. Consequently, this method enhances the accuracy and sensitivity of paper-based colorimetric detection while avoiding potential interferences from non-cellulosic additives. [Display omitted] • Homologous nanocellulose-treated paper hinders coffee-ring and infiltration effects. • CNCs surpass CNFs in preserving paper's structure and fluid transport properties. • CNCs-treated paper sensor improves colorimetric performance in Ni2+/Fe2+ detection. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Analytica Chimica Acta is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.aca.2025.344474 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: N.PAG Subjects: – SubjectFull: Cellulose Type: general – SubjectFull: Cellulose nanocrystals Type: general – SubjectFull: Colorimetric analysis Type: general – SubjectFull: Soil infiltration Type: general – SubjectFull: Statistical accuracy Type: general – SubjectFull: Sensitivity & specificity (Statistics) Type: general – SubjectFull: Nanosensors Type: general – SubjectFull: Capillary flow Type: general Titles: – TitleFull: Homologous nanocellulose modification: A "like cures like" strategy against coffee-ring and infiltration effects in paper-based colorimetric detection. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sun, Linan – PersonEntity: Name: NameFull: Lou, Yafei – PersonEntity: Name: NameFull: Chen, Siyu – PersonEntity: Name: NameFull: Weng, Hongyue – PersonEntity: Name: NameFull: Li, Jiahao – PersonEntity: Name: NameFull: Lin, Zhihui – PersonEntity: Name: NameFull: Tian, Junfei – PersonEntity: Name: NameFull: Cao, Rong IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: Nov2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 00032670 Numbering: – Type: volume Value: 1373 Titles: – TitleFull: Analytica Chimica Acta Type: main |
| ResultId | 1 |
