View in EDS

Breaking and making genes: the genesis of novel traits in plants.

Saved in:
Bibliographic Details
Title: Breaking and making genes: the genesis of novel traits in plants.
Authors: Hamid, Fiza1 (AUTHOR), Arora, Simran1 (AUTHOR), Kumar, Shailesh1 (AUTHOR) shailesh@nipgr.ac.in
Source: New Phytologist. Mar2026, Vol. 249 Issue 6, p2746-2759. 14p.
Subjects: Gene fusion, Plant evolution, Chromosomal rearrangement, Nucleotide sequencing, Metabolism, RNA
Abstract: Summary: Understanding the mechanisms by which plants adapt, evolve, and acquire new traits is crucial for enhancing agricultural resilience and productivity in the face of global challenges. Among the various mechanisms that drive new gene evolution, gene fusion has emerged as a significant yet relatively understudied contributor. It can arise through chromosomal rearrangements or RNA processing mechanisms, merging segments from different genes to produce novel fusion transcripts. In plants, these fusion events have been associated with key biological functions, including the regulation of specialized metabolism, stress responses, and developmental changes. While fusion genes have been extensively studied in humans, mainly due to their oncogenic potential, their prevalence and functional relevance in plants remain relatively underexplored. This review offers a detailed overview of the molecular mechanisms underlying gene fusion formation, highlighting their participation in gene evolution, functional diversification, and plant adaptation. In addition, we discuss current methodologies for detecting and validating fusion events, including high‐throughput sequencing technologies and emerging single‐cell sequencing platforms, and outline promising directions for future research aimed at elucidating their biological significance. Collectively, these insights emphasize the expanding importance of gene fusions in plant biology and underscore the need for further investigation into their regulatory and evolutionary roles. [ABSTRACT FROM AUTHOR]
Copyright of New Phytologist is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 191728003
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Breaking and making genes: the genesis of novel traits in plants.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Hamid%2C+Fiza%22">Hamid, Fiza</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Arora%2C+Simran%22">Arora, Simran</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kumar%2C+Shailesh%22">Kumar, Shailesh</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> shailesh@nipgr.ac.in</i>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22New+Phytologist%22">New Phytologist</searchLink>. Mar2026, Vol. 249 Issue 6, p2746-2759. 14p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Gene+fusion%22">Gene fusion</searchLink><br /><searchLink fieldCode="DE" term="%22Plant+evolution%22">Plant evolution</searchLink><br /><searchLink fieldCode="DE" term="%22Chromosomal+rearrangement%22">Chromosomal rearrangement</searchLink><br /><searchLink fieldCode="DE" term="%22Nucleotide+sequencing%22">Nucleotide sequencing</searchLink><br /><searchLink fieldCode="DE" term="%22Metabolism%22">Metabolism</searchLink><br /><searchLink fieldCode="DE" term="%22RNA%22">RNA</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Summary: Understanding the mechanisms by which plants adapt, evolve, and acquire new traits is crucial for enhancing agricultural resilience and productivity in the face of global challenges. Among the various mechanisms that drive new gene evolution, gene fusion has emerged as a significant yet relatively understudied contributor. It can arise through chromosomal rearrangements or RNA processing mechanisms, merging segments from different genes to produce novel fusion transcripts. In plants, these fusion events have been associated with key biological functions, including the regulation of specialized metabolism, stress responses, and developmental changes. While fusion genes have been extensively studied in humans, mainly due to their oncogenic potential, their prevalence and functional relevance in plants remain relatively underexplored. This review offers a detailed overview of the molecular mechanisms underlying gene fusion formation, highlighting their participation in gene evolution, functional diversification, and plant adaptation. In addition, we discuss current methodologies for detecting and validating fusion events, including high‐throughput sequencing technologies and emerging single‐cell sequencing platforms, and outline promising directions for future research aimed at elucidating their biological significance. Collectively, these insights emphasize the expanding importance of gene fusions in plant biology and underscore the need for further investigation into their regulatory and evolutionary roles. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of New Phytologist is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=191728003
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/nph.70844
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 14
        StartPage: 2746
    Subjects:
      – SubjectFull: Gene fusion
        Type: general
      – SubjectFull: Plant evolution
        Type: general
      – SubjectFull: Chromosomal rearrangement
        Type: general
      – SubjectFull: Nucleotide sequencing
        Type: general
      – SubjectFull: Metabolism
        Type: general
      – SubjectFull: RNA
        Type: general
    Titles:
      – TitleFull: Breaking and making genes: the genesis of novel traits in plants.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Hamid, Fiza
      – PersonEntity:
          Name:
            NameFull: Arora, Simran
      – PersonEntity:
          Name:
            NameFull: Kumar, Shailesh
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 03
              Text: Mar2026
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 0028646X
          Numbering:
            – Type: volume
              Value: 249
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: New Phytologist
              Type: main
ResultId 1