Infrared Emission in the Second Biological Window in LaInO3:Ho3+ Exciting in the First Biological Window.

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Title: Infrared Emission in the Second Biological Window in LaInO3:Ho3+ Exciting in the First Biological Window.
Authors: Vega-Pallauta, Mauricio A.1 (AUTHOR) mvegap@udec.cl, Castillo, Rodrigo2 (AUTHOR), Soler-Carracedo, Kevin3 (AUTHOR), Martin, Inocencio R.4 (AUTHOR)
Source: Journal of Fluorescence. Feb2026, Vol. 36 Issue 2, p1777-1785. 9p.
Subjects: Holmium ions, Luminescence, Diagnostic imaging, Infrared radiation, Perovskite analysis, Rare earth oxides, Infrared imaging
Abstract: In this work, we report the synthesis and characterisation of holmium-doped lanthanum indium oxide as a promising luminescent material for biomedical applications. Samples were prepared via the Pechini sol-gel method and structurally confirmed to crystallise in an orthorhombic perovskite phase (Pnma), with minor In2O3 impurities. Morphological analysis revealed irregular micrometric agglomerates with homogeneous elemental distribution. Optical studies demonstrated efficient absorption at 890 nm (the first biological window) and emission centred at ~ 1200 nm (the second biological window), attributed to the 5I6 → 5I8 transition of Ho3+. The sample doped with 1.0 mol% Ho3+ exhibited the highest emission intensity. Luminescence tests confirmed detectable luminescence through up to 4 mm of blood, highlighting the material's potential for deep-tissue imaging. These results position LaInO3:Ho3+ as a viable candidate for infrared bioimaging working in the first and the second biological windows simultaneously. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Fluorescence is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Infrared Emission in the Second Biological Window in LaInO<subscript>3</subscript>:Ho<superscript>3+</superscript> Exciting in the First Biological Window.
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  Data: <searchLink fieldCode="AR" term="%22Vega-Pallauta%2C+Mauricio+A%2E%22">Vega-Pallauta, Mauricio A.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> mvegap@udec.cl</i><br /><searchLink fieldCode="AR" term="%22Castillo%2C+Rodrigo%22">Castillo, Rodrigo</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Soler-Carracedo%2C+Kevin%22">Soler-Carracedo, Kevin</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Martin%2C+Inocencio+R%2E%22">Martin, Inocencio R.</searchLink><relatesTo>4</relatesTo> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Fluorescence%22">Journal of Fluorescence</searchLink>. Feb2026, Vol. 36 Issue 2, p1777-1785. 9p.
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  Data: <searchLink fieldCode="DE" term="%22Holmium+ions%22">Holmium ions</searchLink><br /><searchLink fieldCode="DE" term="%22Luminescence%22">Luminescence</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnostic+imaging%22">Diagnostic imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Infrared+radiation%22">Infrared radiation</searchLink><br /><searchLink fieldCode="DE" term="%22Perovskite+analysis%22">Perovskite analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Rare+earth+oxides%22">Rare earth oxides</searchLink><br /><searchLink fieldCode="DE" term="%22Infrared+imaging%22">Infrared imaging</searchLink>
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  Data: In this work, we report the synthesis and characterisation of holmium-doped lanthanum indium oxide as a promising luminescent material for biomedical applications. Samples were prepared via the Pechini sol-gel method and structurally confirmed to crystallise in an orthorhombic perovskite phase (Pnma), with minor In2O3 impurities. Morphological analysis revealed irregular micrometric agglomerates with homogeneous elemental distribution. Optical studies demonstrated efficient absorption at 890 nm (the first biological window) and emission centred at ~ 1200 nm (the second biological window), attributed to the 5I6 → 5I8 transition of Ho3+. The sample doped with 1.0 mol% Ho3+ exhibited the highest emission intensity. Luminescence tests confirmed detectable luminescence through up to 4 mm of blood, highlighting the material's potential for deep-tissue imaging. These results position LaInO3:Ho3+ as a viable candidate for infrared bioimaging working in the first and the second biological windows simultaneously. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Journal of Fluorescence is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1007/s10895-025-04674-4
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      – Code: eng
        Text: English
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        PageCount: 9
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      – SubjectFull: Holmium ions
        Type: general
      – SubjectFull: Luminescence
        Type: general
      – SubjectFull: Diagnostic imaging
        Type: general
      – SubjectFull: Infrared radiation
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      – SubjectFull: Perovskite analysis
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      – SubjectFull: Rare earth oxides
        Type: general
      – SubjectFull: Infrared imaging
        Type: general
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      – TitleFull: Infrared Emission in the Second Biological Window in LaInO3:Ho3+ Exciting in the First Biological Window.
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            NameFull: Vega-Pallauta, Mauricio A.
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            NameFull: Castillo, Rodrigo
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            NameFull: Soler-Carracedo, Kevin
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            NameFull: Martin, Inocencio R.
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              Text: Feb2026
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              Y: 2026
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