Sequential reagents release from layered effervescent tablets for simplifying multi-step sample preparation and extraction of metal ions from environmental samples.
Saved in:
| Title: | Sequential reagents release from layered effervescent tablets for simplifying multi-step sample preparation and extraction of metal ions from environmental samples. |
|---|---|
| Authors: | Aggeli, Vasiliki1 (AUTHOR), Toti, Efthimia1 (AUTHOR), Giokas, Dimosthenis L.1 (AUTHOR) dgiokas@uoi.gr |
| Source: | Microchimica Acta. Apr2026, Vol. 193 Issue 4, p1-13. 13p. |
| Subjects: | Chemical sample preparation, Copper analysis, Environmental sampling, Analytical chemistry, Drug tablets |
| Abstract: | Sample preparation typically involves multiple steps to create conditions for separating analytes from the sample matrix. These steps involve the preparation of reagents and materials, their addition into the sample, mixing by external energy input, and timing of each step. All these steps increase analysis time, reduce sample throughput, and require benchtop laboratory equipment and trained personnel. In this work, we report layered effervescent tablets to simplify multistep sample preparation. The tablets consist of layers that dissolve sequentially at a controlled rate, releasing stored, pre-quantified reagents at specific time intervals. As a proof-of-concept demonstration, we designed tablets for the extraction of copper ions, as model analyte, from aqueous solutions. The tablets autonomously perform a series of steps that involve adjustment of pH, dissolution and dispersion of a chelating agent, incubation, mixing and extraction of the metal chelates in a magnetic sorbent by the action of effervescence. The preliminary analytical application of the method to the determination of copper in environmental samples revealed analytical features, which are comparable to standard laboratory practices (recoveries > 80%, RSD < 8%). In this manner it is demonstrated that layered effervescent tablets can be a promising tool for simplifying multistep sample preparation by reducing reliance on human and technical resources and allowing extractions to be performed with minimal intervention and basic infrastructure. [ABSTRACT FROM AUTHOR] |
| Copyright of Microchimica Acta is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: egs DbLabel: Engineering Source An: 193085350 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Sequential reagents release from layered effervescent tablets for simplifying multi-step sample preparation and extraction of metal ions from environmental samples. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Aggeli%2C+Vasiliki%22">Aggeli, Vasiliki</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Toti%2C+Efthimia%22">Toti, Efthimia</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Giokas%2C+Dimosthenis+L%2E%22">Giokas, Dimosthenis L.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> dgiokas@uoi.gr</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Microchimica+Acta%22">Microchimica Acta</searchLink>. Apr2026, Vol. 193 Issue 4, p1-13. 13p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Chemical+sample+preparation%22">Chemical sample preparation</searchLink><br /><searchLink fieldCode="DE" term="%22Copper+analysis%22">Copper analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Environmental+sampling%22">Environmental sampling</searchLink><br /><searchLink fieldCode="DE" term="%22Analytical+chemistry%22">Analytical chemistry</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+tablets%22">Drug tablets</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Sample preparation typically involves multiple steps to create conditions for separating analytes from the sample matrix. These steps involve the preparation of reagents and materials, their addition into the sample, mixing by external energy input, and timing of each step. All these steps increase analysis time, reduce sample throughput, and require benchtop laboratory equipment and trained personnel. In this work, we report layered effervescent tablets to simplify multistep sample preparation. The tablets consist of layers that dissolve sequentially at a controlled rate, releasing stored, pre-quantified reagents at specific time intervals. As a proof-of-concept demonstration, we designed tablets for the extraction of copper ions, as model analyte, from aqueous solutions. The tablets autonomously perform a series of steps that involve adjustment of pH, dissolution and dispersion of a chelating agent, incubation, mixing and extraction of the metal chelates in a magnetic sorbent by the action of effervescence. The preliminary analytical application of the method to the determination of copper in environmental samples revealed analytical features, which are comparable to standard laboratory practices (recoveries > 80%, RSD < 8%). In this manner it is demonstrated that layered effervescent tablets can be a promising tool for simplifying multistep sample preparation by reducing reliance on human and technical resources and allowing extractions to be performed with minimal intervention and basic infrastructure. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Microchimica Acta is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=193085350 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00604-026-07963-2 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 1 Subjects: – SubjectFull: Chemical sample preparation Type: general – SubjectFull: Copper analysis Type: general – SubjectFull: Environmental sampling Type: general – SubjectFull: Analytical chemistry Type: general – SubjectFull: Drug tablets Type: general Titles: – TitleFull: Sequential reagents release from layered effervescent tablets for simplifying multi-step sample preparation and extraction of metal ions from environmental samples. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Aggeli, Vasiliki – PersonEntity: Name: NameFull: Toti, Efthimia – PersonEntity: Name: NameFull: Giokas, Dimosthenis L. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: Apr2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 00263672 Numbering: – Type: volume Value: 193 – Type: issue Value: 4 Titles: – TitleFull: Microchimica Acta Type: main |
| ResultId | 1 |
