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Plasmonic Switches Fabricated via DNA Origami for Reconfigurable Logic Architectures.

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Title: Plasmonic Switches Fabricated via DNA Origami for Reconfigurable Logic Architectures.
Authors: Sabitha, R.1 (AUTHOR) sabitha5@gmail.com, Sydulu, Shaik John1 (AUTHOR) Johny.ciet@gmail.com, Karthik, S.1 (AUTHOR) deancse@snsct.org, Kavitha, M. S.1 (AUTHOR) kavitha589@gmail.com
Source: NANO (1793-2920). Aug2026, Vol. 21 Issue 10, p1-13. 13p.
Subjects: Optical computing, Optical switches, Nanophotonics, Silver nanoparticles, DNA folding
Abstract: This paper reports the fabrication of DNA origami-directed plasmonic logic gates based on the site-specific assembly of silver nanoparticles (AgNPs) to nanoscale optical computing, providing a path to high-performance and reliable computing. The colloidal stability is shown by size-controlled formation of AgNPs, giving a mean diameter of 24.5 nm ± 4.2 nm and a plasmonic resonance peak at 412 nm. Using the caDNAno designer, such DNA origami scaffolds had > 95 folding efficiency, produced relatively well-defined 90 nm (length) by 60 nm (width) rectangular structures, as visualized by AFM and confirmed by gel electrophoresis. Thiol-DNA hybridization allowed anchoring the AgNPs on defined capture surfaces of the origami with nanometric accuracy (in the range of 2 nm) and high anchor efficiency (88.3% ± 3.4%). The implementation of four logic gate configurations, namely AND, OR, NOT and XOR, was carried out. The largest shift of 15.2 nm ± 1.1 nm was observed in the AND gate after being activated by dual input, and selective single-input activation of 13.6 nm ± 1.2 nm was seen in XOR gates. All the gates produced > 9 5 % output fidelity and maintained switching time of 5.8–8.4 s using high signal-to-noise ratios (> 20:1). Crosstalk (< 3 nm) and error rates (4.2 ± 0.8) were low under stress when large origami patterns were multigate integrated. These results open a sustainable and scale-up platform of photonic logic functions at the molecular scale. The paper reports the fabrication of DNA origami-directed plasmonic logic gates by site-specific assembly of silver nanoparticles (AgNPs), enabling nanoscale optical computing with high performance and reliability. It demonstrates programmable AND, OR, NOT, and XOR logic gates with high output fidelity (95%) and fast switching times (around 6 seconds), supported by precise nanoparticle placement within 2 nm and stable plasmonic resonance shifts. The work also shows scalability by integrating multiple gates on extended DNA origami scaffolds with low crosstalk and error rates, representing a promising step toward low-power, molecular-scale photonic computing and advanced nanophotonic circuits. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
Description
Abstract:This paper reports the fabrication of DNA origami-directed plasmonic logic gates based on the site-specific assembly of silver nanoparticles (AgNPs) to nanoscale optical computing, providing a path to high-performance and reliable computing. The colloidal stability is shown by size-controlled formation of AgNPs, giving a mean diameter of 24.5 nm ± 4.2 nm and a plasmonic resonance peak at 412 nm. Using the caDNAno designer, such DNA origami scaffolds had > 95 folding efficiency, produced relatively well-defined 90 nm (length) by 60 nm (width) rectangular structures, as visualized by AFM and confirmed by gel electrophoresis. Thiol-DNA hybridization allowed anchoring the AgNPs on defined capture surfaces of the origami with nanometric accuracy (in the range of 2 nm) and high anchor efficiency (88.3% ± 3.4%). The implementation of four logic gate configurations, namely AND, OR, NOT and XOR, was carried out. The largest shift of 15.2 nm ± 1.1 nm was observed in the AND gate after being activated by dual input, and selective single-input activation of 13.6 nm ± 1.2 nm was seen in XOR gates. All the gates produced > 9 5 % output fidelity and maintained switching time of 5.8–8.4 s using high signal-to-noise ratios (> 20:1). Crosstalk (< 3 nm) and error rates (4.2 ± 0.8) were low under stress when large origami patterns were multigate integrated. These results open a sustainable and scale-up platform of photonic logic functions at the molecular scale. The paper reports the fabrication of DNA origami-directed plasmonic logic gates by site-specific assembly of silver nanoparticles (AgNPs), enabling nanoscale optical computing with high performance and reliability. It demonstrates programmable AND, OR, NOT, and XOR logic gates with high output fidelity (95%) and fast switching times (around 6 seconds), supported by precise nanoparticle placement within 2 nm and stable plasmonic resonance shifts. The work also shows scalability by integrating multiple gates on extended DNA origami scaffolds with low crosstalk and error rates, representing a promising step toward low-power, molecular-scale photonic computing and advanced nanophotonic circuits. [ABSTRACT FROM AUTHOR]
ISSN:17932920
DOI:10.1142/S1793292026500074