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Production and functional applications of fructooligosaccharides and their core bioactive components.

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Title: Production and functional applications of fructooligosaccharides and their core bioactive components.
Authors: Su, Xueli1,2 (AUTHOR), Lin, Yu3 (AUTHOR), Li, Zhenglong4 (AUTHOR), Zeng, Wei1,2,3 (AUTHOR) 19144204979@163.com, Duan, Xiaoqun1,2 (AUTHOR) ztwh1990@126.com
Source: World Journal of Microbiology & Biotechnology. Apr2026, Vol. 42 Issue 4, p1-20. 20p.
Subjects: Fructooligosaccharides, Gut microbiota, Trisaccharides, Prebiotics
Abstract: Fructooligosaccharides (FOS) are widely recognized as functional prebiotics with diverse physiological activities, including modulation of the gut microbiota, anti-diabetic effects, enhancement of immune responses, and other health promoting functions. Based on their terminal residues, FOS can be classified into fructose-terminated fructooligosaccharides (Fn, n = 2 ~ 9) and glucose-terminated fructooligosaccharides (GFn, n = 2 ~ 8). Compared with Fn, GFn exhibit distinct advantages in terms of raw material availability, production processes, manufacturing costs, and application potential, and therefore have received more attention. Among GFn, kestoses (GF2), nystose (GF3), and fructosylnystose (GF4) represent the core bioactive components and display distinct physiological effects. This review critically summarizes the current advances in the production and purification techniques of GFn mixtures and their core components (GF2, GF3 and GF4), with particular emphasis on 1-kestose due to its superior efficacy in gut microbiota modulation, aiming to provide valuable insights to support future production, application and development. [ABSTRACT FROM AUTHOR]
Copyright of World Journal of Microbiology & Biotechnology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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  Data: Production and functional applications of fructooligosaccharides and their core bioactive components.
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  Data: <searchLink fieldCode="JN" term="%22World+Journal+of+Microbiology+%26+Biotechnology%22">World Journal of Microbiology & Biotechnology</searchLink>. Apr2026, Vol. 42 Issue 4, p1-20. 20p.
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  Data: <searchLink fieldCode="DE" term="%22Fructooligosaccharides%22">Fructooligosaccharides</searchLink><br /><searchLink fieldCode="DE" term="%22Gut+microbiota%22">Gut microbiota</searchLink><br /><searchLink fieldCode="DE" term="%22Trisaccharides%22">Trisaccharides</searchLink><br /><searchLink fieldCode="DE" term="%22Prebiotics%22">Prebiotics</searchLink>
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  Label: Abstract
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  Data: Fructooligosaccharides (FOS) are widely recognized as functional prebiotics with diverse physiological activities, including modulation of the gut microbiota, anti-diabetic effects, enhancement of immune responses, and other health promoting functions. Based on their terminal residues, FOS can be classified into fructose-terminated fructooligosaccharides (Fn, n = 2 ~ 9) and glucose-terminated fructooligosaccharides (GFn, n = 2 ~ 8). Compared with Fn, GFn exhibit distinct advantages in terms of raw material availability, production processes, manufacturing costs, and application potential, and therefore have received more attention. Among GFn, kestoses (GF2), nystose (GF3), and fructosylnystose (GF4) represent the core bioactive components and display distinct physiological effects. This review critically summarizes the current advances in the production and purification techniques of GFn mixtures and their core components (GF2, GF3 and GF4), with particular emphasis on 1-kestose due to its superior efficacy in gut microbiota modulation, aiming to provide valuable insights to support future production, application and development. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of World Journal of Microbiology & Biotechnology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1007/s11274-026-04944-8
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        Text: English
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        Type: general
      – SubjectFull: Gut microbiota
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      – SubjectFull: Trisaccharides
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      – SubjectFull: Prebiotics
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              Text: Apr2026
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              Y: 2026
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