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Synthesis of discodermolide intermediates from engineered polyketides

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Title: Synthesis of discodermolide intermediates from engineered polyketides
Authors: Burlingame, Mark A. burlingame@kosan.com, Mendoza, Esteban1, Ashley, Gary W.1, Myles, David C.1
Source: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Feb2006, Vol. 47 Issue 7, p1209-1211. 3p.
Subjects: Polyketides, Acrylonitrile, Cyclic compounds, Carbon compounds
Abstract: Abstract: Key intermediates used in Smith’s total synthesis of discodermolide were synthesized from an engineered polyketide made via precursor feeding to genetically modified polyketide producing bacteria. [Copyright &y& Elsevier]
Copyright of Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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Header DbId: egs
DbLabel: Engineering Source
An: 19394766
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Synthesis of discodermolide intermediates from engineered polyketides
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  Data: <searchLink fieldCode="AR" term="%22Burlingame%2C+Mark+A%2E%22">Burlingame, Mark A.</searchLink><i> burlingame@kosan.com</i><br /><searchLink fieldCode="AR" term="%22Mendoza%2C+Esteban%22">Mendoza, Esteban</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ashley%2C+Gary+W%2E%22">Ashley, Gary W.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Myles%2C+David+C%2E%22">Myles, David C.</searchLink><relatesTo>1</relatesTo>
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  Data: <searchLink fieldCode="DE" term="%22Polyketides%22">Polyketides</searchLink><br /><searchLink fieldCode="DE" term="%22Acrylonitrile%22">Acrylonitrile</searchLink><br /><searchLink fieldCode="DE" term="%22Cyclic+compounds%22">Cyclic compounds</searchLink><br /><searchLink fieldCode="DE" term="%22Carbon+compounds%22">Carbon compounds</searchLink>
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  Data: Abstract: Key intermediates used in Smith’s total synthesis of discodermolide were synthesized from an engineered polyketide made via precursor feeding to genetically modified polyketide producing bacteria. [Copyright &y& Elsevier]
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  Data: <i>Copyright of Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1016/j.tetlet.2005.12.010
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        Text: English
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        Type: general
      – SubjectFull: Acrylonitrile
        Type: general
      – SubjectFull: Cyclic compounds
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      – SubjectFull: Carbon compounds
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      – TitleFull: Synthesis of discodermolide intermediates from engineered polyketides
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            NameFull: Ashley, Gary W.
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              Text: Feb2006
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