Catalytic Asymmetric Construction of Medium-Sized Ring Systems with Single Axial or Inherent Chiral Element.

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Title: Catalytic Asymmetric Construction of Medium-Sized Ring Systems with Single Axial or Inherent Chiral Element.
Authors: Xu, Jiahao1 (AUTHOR), Liang, Mengjia1 (AUTHOR), Wei, Liwen1 (AUTHOR), Yang, Xing1 (AUTHOR) xingyang@hunnu.edu.cn
Source: Synthesis. Jun2026, Vol. 58 Issue 12, p1321-1342. 22p.
Subjects: Chirality element, Cyclic compounds, Enantioselective catalysis, Chirality, Pharmaceutical chemistry, Chemical synthesis, Asymmetric synthesis
Abstract: Inherently and axially chiral medium-sized cyclic compounds play an essential role across multiple domains—from medicinal chemistry and advanced materials to asymmetric catalysis—due to their unique structural and functional properties. With rapid innovation in synthetic methodologies over recent years, this review provides a systematic summary and discussion of representative advances in the synthesis of medium-sized ring systems featuring single axial or inherent chirality. [ABSTRACT FROM AUTHOR]
Copyright of Synthesis is the property of Georg Thieme Verlag Stuttgart and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 194452667
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PubTypeId: academicJournal
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  Data: Catalytic Asymmetric Construction of Medium-Sized Ring Systems with Single Axial or Inherent Chiral Element.
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  Data: <searchLink fieldCode="AR" term="%22Xu%2C+Jiahao%22">Xu, Jiahao</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liang%2C+Mengjia%22">Liang, Mengjia</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wei%2C+Liwen%22">Wei, Liwen</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Xing%22">Yang, Xing</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> xingyang@hunnu.edu.cn</i>
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  Data: <searchLink fieldCode="JN" term="%22Synthesis%22">Synthesis</searchLink>. Jun2026, Vol. 58 Issue 12, p1321-1342. 22p.
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  Data: <searchLink fieldCode="DE" term="%22Chirality+element%22">Chirality element</searchLink><br /><searchLink fieldCode="DE" term="%22Cyclic+compounds%22">Cyclic compounds</searchLink><br /><searchLink fieldCode="DE" term="%22Enantioselective+catalysis%22">Enantioselective catalysis</searchLink><br /><searchLink fieldCode="DE" term="%22Chirality%22">Chirality</searchLink><br /><searchLink fieldCode="DE" term="%22Pharmaceutical+chemistry%22">Pharmaceutical chemistry</searchLink><br /><searchLink fieldCode="DE" term="%22Chemical+synthesis%22">Chemical synthesis</searchLink><br /><searchLink fieldCode="DE" term="%22Asymmetric+synthesis%22">Asymmetric synthesis</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Inherently and axially chiral medium-sized cyclic compounds play an essential role across multiple domains—from medicinal chemistry and advanced materials to asymmetric catalysis—due to their unique structural and functional properties. With rapid innovation in synthetic methodologies over recent years, this review provides a systematic summary and discussion of representative advances in the synthesis of medium-sized ring systems featuring single axial or inherent chirality. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Synthesis is the property of Georg Thieme Verlag Stuttgart and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1055/a-2791-3501
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 22
        StartPage: 1321
    Subjects:
      – SubjectFull: Chirality element
        Type: general
      – SubjectFull: Cyclic compounds
        Type: general
      – SubjectFull: Enantioselective catalysis
        Type: general
      – SubjectFull: Chirality
        Type: general
      – SubjectFull: Pharmaceutical chemistry
        Type: general
      – SubjectFull: Chemical synthesis
        Type: general
      – SubjectFull: Asymmetric synthesis
        Type: general
    Titles:
      – TitleFull: Catalytic Asymmetric Construction of Medium-Sized Ring Systems with Single Axial or Inherent Chiral Element.
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            NameFull: Xu, Jiahao
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            NameFull: Liang, Mengjia
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            NameFull: Wei, Liwen
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            NameFull: Yang, Xing
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            – D: 15
              M: 06
              Text: Jun2026
              Type: published
              Y: 2026
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              Value: 58
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            – TitleFull: Synthesis
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