Thermosensitive magnetic polymer particles as contactless controllable drug carriers
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| Title: | Thermosensitive magnetic polymer particles as contactless controllable drug carriers |
|---|---|
| Authors: | Müller-Schulte, Detlef1 detlef.mueller2@post.rwth-aachen.de, Schmitz-Rode, Thomas2 |
| Source: | Journal of Magnetism & Magnetic Materials. Jul2006, Vol. 302 Issue 1, p267-271. 5p. |
| Subjects: | Nanoparticles, Magnetic fields, Transition metals, Magnetization |
| Abstract: | Abstract: Spherically shaped thermosensitive micro and nanoparticles based on N-isopropylacrylamide were synthesized using a novel inverse suspension polymerization technique which enables a bead formation within minutes. In addition to the rapidity, the suspension procedure provides an effective platform for the encapsulation of magnetic colloids and simultaneous drug analogous substances. The presence of the magnetic colloids allows an inductive heating of the particles using an alternating magnetic field above the polymer transition temperature (>35°C). This results in a pronounced de-swelling accompanied by a release of the encapsulated substances. The potential of this technology for a new contactless controllable drug releasing approach is exemplarily demonstrated using rhodamine B and methylene blue as drug analogous substances. [Copyright &y& Elsevier] |
| Copyright of Journal of Magnetism & Magnetic Materials is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 20261034 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Thermosensitive magnetic polymer particles as contactless controllable drug carriers – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Müller-Schulte%2C+Detlef%22">Müller-Schulte, Detlef</searchLink><relatesTo>1</relatesTo><i> detlef.mueller2@post.rwth-aachen.de</i><br /><searchLink fieldCode="AR" term="%22Schmitz-Rode%2C+Thomas%22">Schmitz-Rode, Thomas</searchLink><relatesTo>2</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Magnetism+%26+Magnetic+Materials%22">Journal of Magnetism & Magnetic Materials</searchLink>. Jul2006, Vol. 302 Issue 1, p267-271. 5p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Nanoparticles%22">Nanoparticles</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+fields%22">Magnetic fields</searchLink><br /><searchLink fieldCode="DE" term="%22Transition+metals%22">Transition metals</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetization%22">Magnetization</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Abstract: Spherically shaped thermosensitive micro and nanoparticles based on N-isopropylacrylamide were synthesized using a novel inverse suspension polymerization technique which enables a bead formation within minutes. In addition to the rapidity, the suspension procedure provides an effective platform for the encapsulation of magnetic colloids and simultaneous drug analogous substances. The presence of the magnetic colloids allows an inductive heating of the particles using an alternating magnetic field above the polymer transition temperature (>35°C). This results in a pronounced de-swelling accompanied by a release of the encapsulated substances. The potential of this technology for a new contactless controllable drug releasing approach is exemplarily demonstrated using rhodamine B and methylene blue as drug analogous substances. [Copyright &y& Elsevier] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Magnetism & Magnetic Materials is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=20261034 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jmmm.2005.05.043 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 267 Subjects: – SubjectFull: Nanoparticles Type: general – SubjectFull: Magnetic fields Type: general – SubjectFull: Transition metals Type: general – SubjectFull: Magnetization Type: general Titles: – TitleFull: Thermosensitive magnetic polymer particles as contactless controllable drug carriers Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Müller-Schulte, Detlef – PersonEntity: Name: NameFull: Schmitz-Rode, Thomas IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: Jul2006 Type: published Y: 2006 Identifiers: – Type: issn-print Value: 03048853 Numbering: – Type: volume Value: 302 – Type: issue Value: 1 Titles: – TitleFull: Journal of Magnetism & Magnetic Materials Type: main |
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