Thermosensitive magnetic polymer particles as contactless controllable drug carriers

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Title: Thermosensitive magnetic polymer particles as contactless controllable drug carriers
Authors: Müller-Schulte, Detlef1 detlef.mueller2@post.rwth-aachen.de, Schmitz-Rode, Thomas2
Source: Journal of Magnetism & Magnetic Materials. Jul2006, Vol. 302 Issue 1, p267-271. 5p.
Subjects: Nanoparticles, Magnetic fields, Transition metals, Magnetization
Abstract: Abstract: Spherically shaped thermosensitive micro and nanoparticles based on N-isopropylacrylamide were synthesized using a novel inverse suspension polymerization technique which enables a bead formation within minutes. In addition to the rapidity, the suspension procedure provides an effective platform for the encapsulation of magnetic colloids and simultaneous drug analogous substances. The presence of the magnetic colloids allows an inductive heating of the particles using an alternating magnetic field above the polymer transition temperature (>35°C). This results in a pronounced de-swelling accompanied by a release of the encapsulated substances. The potential of this technology for a new contactless controllable drug releasing approach is exemplarily demonstrated using rhodamine B and methylene blue as drug analogous substances. [Copyright &y& Elsevier]
Copyright of Journal of Magnetism & Magnetic Materials is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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Header DbId: egs
DbLabel: Engineering Source
An: 20261034
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Thermosensitive magnetic polymer particles as contactless controllable drug carriers
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  Data: <searchLink fieldCode="AR" term="%22Müller-Schulte%2C+Detlef%22">Müller-Schulte, Detlef</searchLink><relatesTo>1</relatesTo><i> detlef.mueller2@post.rwth-aachen.de</i><br /><searchLink fieldCode="AR" term="%22Schmitz-Rode%2C+Thomas%22">Schmitz-Rode, Thomas</searchLink><relatesTo>2</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Magnetism+%26+Magnetic+Materials%22">Journal of Magnetism & Magnetic Materials</searchLink>. Jul2006, Vol. 302 Issue 1, p267-271. 5p.
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  Data: <searchLink fieldCode="DE" term="%22Nanoparticles%22">Nanoparticles</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+fields%22">Magnetic fields</searchLink><br /><searchLink fieldCode="DE" term="%22Transition+metals%22">Transition metals</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetization%22">Magnetization</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Abstract: Spherically shaped thermosensitive micro and nanoparticles based on N-isopropylacrylamide were synthesized using a novel inverse suspension polymerization technique which enables a bead formation within minutes. In addition to the rapidity, the suspension procedure provides an effective platform for the encapsulation of magnetic colloids and simultaneous drug analogous substances. The presence of the magnetic colloids allows an inductive heating of the particles using an alternating magnetic field above the polymer transition temperature (>35°C). This results in a pronounced de-swelling accompanied by a release of the encapsulated substances. The potential of this technology for a new contactless controllable drug releasing approach is exemplarily demonstrated using rhodamine B and methylene blue as drug analogous substances. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Magnetism & Magnetic Materials is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.jmmm.2005.05.043
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      – Code: eng
        Text: English
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        PageCount: 5
        StartPage: 267
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      – SubjectFull: Nanoparticles
        Type: general
      – SubjectFull: Magnetic fields
        Type: general
      – SubjectFull: Transition metals
        Type: general
      – SubjectFull: Magnetization
        Type: general
    Titles:
      – TitleFull: Thermosensitive magnetic polymer particles as contactless controllable drug carriers
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            NameFull: Müller-Schulte, Detlef
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            NameFull: Schmitz-Rode, Thomas
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              Text: Jul2006
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              Y: 2006
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