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Application of MLE method to range determination with induced β+ activity in hadron therapy

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Title: Application of MLE method to range determination with induced β+ activity in hadron therapy
Authors: Inaniwa, T.1, Kohno, T.1 kohno@es.titech.ac.jp, Tomitani, T.2, Kanazawa, M.2, Sato, S.2, Urakabe, E.3, Kanai, T.3
Source: Nuclear Instruments & Methods in Physics Research Section A. Jun2006, Vol. 562 Issue 2, p1017-1019. 3p.
Subjects: Ions, Irradiation, Electrons, Properties of matter
Abstract: Abstract: We proposed to apply the MLE method for determining the range of heavy ions and demonstrated the effectiveness of this method by experiments with 12C beams. We performed irradiation experiments with stable 12C ions of mono-energetic 290MeV/u to a water, a polyethylene and a PMMA target. The theoretical ranges for 12C ions of 290MeV/u in these targets are 160.5, 157.9 and 139.8mm, respectively. The annihilation events from positron emitters generated by 12C ions were detected with a positron camera for 500s just after the irradiation. To evaluate the range of 12C ions, the MLE method was applied to the annihilation gamma ray distribution. The derived ranges for the three targets were 160.6, 158.9 and 140.4mm, respectively. Therefore, we can conclude that the range of 12C ions was determined within an accuracy of 1.0mm for all targets. [Copyright &y& Elsevier]
Copyright of Nuclear Instruments & Methods in Physics Research Section A is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 21253152
AccessLevel: 6
PubType: Academic Journal
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  Data: Application of MLE method to range determination with induced β<superscript>+</superscript> activity in hadron therapy
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  Data: <searchLink fieldCode="AR" term="%22Inaniwa%2C+T%2E%22">Inaniwa, T.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Kohno%2C+T%2E%22">Kohno, T.</searchLink><relatesTo>1</relatesTo><i> kohno@es.titech.ac.jp</i><br /><searchLink fieldCode="AR" term="%22Tomitani%2C+T%2E%22">Tomitani, T.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Kanazawa%2C+M%2E%22">Kanazawa, M.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Sato%2C+S%2E%22">Sato, S.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Urakabe%2C+E%2E%22">Urakabe, E.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Kanai%2C+T%2E%22">Kanai, T.</searchLink><relatesTo>3</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Nuclear+Instruments+%26+Methods+in+Physics+Research+Section+A%22">Nuclear Instruments & Methods in Physics Research Section A</searchLink>. Jun2006, Vol. 562 Issue 2, p1017-1019. 3p.
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  Data: <searchLink fieldCode="DE" term="%22Ions%22">Ions</searchLink><br /><searchLink fieldCode="DE" term="%22Irradiation%22">Irradiation</searchLink><br /><searchLink fieldCode="DE" term="%22Electrons%22">Electrons</searchLink><br /><searchLink fieldCode="DE" term="%22Properties+of+matter%22">Properties of matter</searchLink>
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  Data: Abstract: We proposed to apply the MLE method for determining the range of heavy ions and demonstrated the effectiveness of this method by experiments with 12C beams. We performed irradiation experiments with stable 12C ions of mono-energetic 290MeV/u to a water, a polyethylene and a PMMA target. The theoretical ranges for 12C ions of 290MeV/u in these targets are 160.5, 157.9 and 139.8mm, respectively. The annihilation events from positron emitters generated by 12C ions were detected with a positron camera for 500s just after the irradiation. To evaluate the range of 12C ions, the MLE method was applied to the annihilation gamma ray distribution. The derived ranges for the three targets were 160.6, 158.9 and 140.4mm, respectively. Therefore, we can conclude that the range of 12C ions was determined within an accuracy of 1.0mm for all targets. [Copyright &y& Elsevier]
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  Data: <i>Copyright of Nuclear Instruments & Methods in Physics Research Section A is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1016/j.nima.2006.02.085
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              Text: Jun2006
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