Bibliographic Details
| Title: |
Efficient enantioselective synthesis of orthogonally protected (R)-α-alkylserines compatible with the solid phase peptide synthesis |
| Authors: |
Vassiliou, Stamatia1, Yiotakis, Athanasios1, Magriotis, Plato A.2 plato.magriotis@nyu.edu |
| Source: |
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Oct2006, Vol. 47 Issue 41, p7339-7341. 3p. |
| Subjects: |
Amino acids, Organic acids, Peptide synthesis, Asymmetry (Chemistry) |
| Abstract: |
Abstract: The Schöllkopf methodology for the asymmetric synthesis of α-amino acids, which was previously not applicable to the construction of quaternary α-amino acids, has been rendered not only suitable but also practical for this purpose and applied to a highly efficient enantioselective synthesis of orthogonally protected (R)-α-alkylserines suitable for the solid phase synthesis. [Copyright &y& Elsevier] |
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| Database: |
Engineering Source |