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Mapping of the preferred direction in the motor cortex.

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Title: Mapping of the preferred direction in the motor cortex.
Authors: Georgopouios, Apostolos P.1,2,3,4,5,6 omega@umn.edu, Merchant, Hugo1,2,7, Naselaris, Thomas1,2, Amirikian, Bagrat1,2,5
Source: Proceedings of the National Academy of Sciences of the United States of America. 6/26/2007, Vol. 104 Issue 26, p11068-11072. 5p. 3 Graphs.
Subjects: Motor cortex, Microelectrodes, Frontal lobe, Columns, Extremities (Anatomy), Cerebral cortex
Abstract: Directional tuning is a basic functional property of cell activity in the motor cortex. Previous work has indicated that cells with similar preferred directions are organized in columns perpendicular to the cortical surface. Here we show that these columns are organized in an orderly fashion in the tangential dimension on the cortical surface. Based on a large number of microelectrode penetrations and systematic exploration of the proximal arm area of the motor cortex while monkeys made free reaching 3D movements, it was estimated that (i) directional minicolumns are ≈30 μm in width, (ii) minicolumns with similar preferred directions tend to occur in doublets or triplets, and (ii,) such minicolumns tend to repeat every ≈240 μm (estimated width of a column), with inter-mediate preferred directions represented in a gradient. These findings provide evidence for an orderly mapping of the preferred direction in the motor cortex. [ABSTRACT FROM AUTHOR]
Copyright of Proceedings of the National Academy of Sciences of the United States of America is the property of National Academy of Sciences and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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PubType: Academic Journal
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  Data: Mapping of the preferred direction in the motor cortex.
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  Data: <searchLink fieldCode="DE" term="%22Motor+cortex%22">Motor cortex</searchLink><br /><searchLink fieldCode="DE" term="%22Microelectrodes%22">Microelectrodes</searchLink><br /><searchLink fieldCode="DE" term="%22Frontal+lobe%22">Frontal lobe</searchLink><br /><searchLink fieldCode="DE" term="%22Columns%22">Columns</searchLink><br /><searchLink fieldCode="DE" term="%22Extremities+%28Anatomy%29%22">Extremities (Anatomy)</searchLink><br /><searchLink fieldCode="DE" term="%22Cerebral+cortex%22">Cerebral cortex</searchLink>
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  Data: Directional tuning is a basic functional property of cell activity in the motor cortex. Previous work has indicated that cells with similar preferred directions are organized in columns perpendicular to the cortical surface. Here we show that these columns are organized in an orderly fashion in the tangential dimension on the cortical surface. Based on a large number of microelectrode penetrations and systematic exploration of the proximal arm area of the motor cortex while monkeys made free reaching 3D movements, it was estimated that (i) directional minicolumns are ≈30 μm in width, (ii) minicolumns with similar preferred directions tend to occur in doublets or triplets, and (ii,) such minicolumns tend to repeat every ≈240 μm (estimated width of a column), with inter-mediate preferred directions represented in a gradient. These findings provide evidence for an orderly mapping of the preferred direction in the motor cortex. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Proceedings of the National Academy of Sciences of the United States of America is the property of National Academy of Sciences and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1073/pnas.0611597104
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      – Code: eng
        Text: English
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        PageCount: 5
        StartPage: 11068
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      – SubjectFull: Motor cortex
        Type: general
      – SubjectFull: Microelectrodes
        Type: general
      – SubjectFull: Frontal lobe
        Type: general
      – SubjectFull: Columns
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      – SubjectFull: Extremities (Anatomy)
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      – TitleFull: Mapping of the preferred direction in the motor cortex.
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            NameFull: Merchant, Hugo
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            – D: 26
              M: 06
              Text: 6/26/2007
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              Y: 2007
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