Preparation of biomolecule gel matrices for electron microscopy
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| Title: | Preparation of biomolecule gel matrices for electron microscopy |
|---|---|
| Authors: | Padalkar, Sonal1, Zhao, Jianxiu2, Stuart, Kate3, Panitch, Alyssa3, Rickus, Jenna2,3, Stanciu, Lia1,3 lstanciu@purdue.edu |
| Source: | Ultramicroscopy. Mar2008, Vol. 108 Issue 4, p309-313. 5p. |
| Subjects: | Colloids, Electron microscopy, Particles (Nuclear physics), Universal algebra |
| Abstract: | Abstract: We report a new sample preparation method that allows the direct transmission electron microscopy evaluation of the architectural characteristics of biomolecules entrapped in gel matrices. We demonstrate that this sample preparation technique can be used for the identification and ultrastructural characterization of liposomes, collagen I and collagen III embedded in gel matrices, and has the potential to be useful for transmission electron microscopy (TEM) characterization of other biomolecule–gel matrix systems. [Copyright &y& Elsevier] |
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| Database: | Engineering Source |
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