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Genotoxicity evaluation and a primary risk assessment of organic pollutants in the drinking water sources of Nanjing, China

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Title: Genotoxicity evaluation and a primary risk assessment of organic pollutants in the drinking water sources of Nanjing, China
Authors: LI, Yi-qiang1,2, WU, Yu-lin1, CHEN, Yuan-gao1, KONG, Zhi-ming1 zmkong@nju.edu.cn
Source: Journal of Environmental Sciences (Elsevier). Sep2006, Vol. 18 Issue 5, p983-988. 6p.
Subjects: Drinking water, Waste products, Water supply, Genetic toxicology
Abstract: Abstract: An increasing number of industrial, agricultural, and commercial chemicals in the aquatic environment leads to various deleterious effects on organisms, which is becoming an increasingly serious problem in China. In this study, the comet assay was conducted to investigate the genotoxicity to human body caused by organic concentrates in the drinking water sources of Nanjing City from Yangtze River of China, and health and ecology risk due to expose to these organic pollutants were evaluated with the multimedia environmental assessment system (MEAS). For all the water samples, they were collected from four different locations in the drinking water sourer samples, es of Nanjing City. The results of the comet assay showed that all the organic concentrates from the water samples could induce different levels DNA damages on human peripheral blood lymphocytes, and a statistically significant difference (p<0.01) was observed compared with the solvent control, which demonstrated the genotoxicity was in existence. According to the ambient severity (AS) of individual compound, we had sorted out the main organic pollutants in the drinking water source of the four waterworks, and the results showed that there was some potential hazard to human body for all the source water, namely the total ambient severity (TAS) of health for each water source was more than I. However, the TAS of ecology for each water source was less than 1, which indicated that it was safe to ecology. The results of this investigation demonstrate the application of the comet assay and the MEAS in aquatic environmental monitoring studies, and the comet assay found to be fast, sensitive, and suitable for genotoxicity monitoring programs of drinking water source. [Copyright &y& Elsevier]
Copyright of Journal of Environmental Sciences (Elsevier) is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Genotoxicity evaluation and a primary risk assessment of organic pollutants in the drinking water sources of Nanjing, China
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Journal+of+Environmental+Sciences+%28Elsevier%29%22&quot;&gt;Journal of Environmental Sciences (Elsevier)&lt;/searchLink&gt;. Sep2006, Vol. 18 Issue 5, p983-988. 6p.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Drinking+water%22&quot;&gt;Drinking water&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Waste+products%22&quot;&gt;Waste products&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Water+supply%22&quot;&gt;Water supply&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Genetic+toxicology%22&quot;&gt;Genetic toxicology&lt;/searchLink&gt;
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  Label: Abstract
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  Data: Abstract: An increasing number of industrial, agricultural, and commercial chemicals in the aquatic environment leads to various deleterious effects on organisms, which is becoming an increasingly serious problem in China. In this study, the comet assay was conducted to investigate the genotoxicity to human body caused by organic concentrates in the drinking water sources of Nanjing City from Yangtze River of China, and health and ecology risk due to expose to these organic pollutants were evaluated with the multimedia environmental assessment system (MEAS). For all the water samples, they were collected from four different locations in the drinking water sourer samples, es of Nanjing City. The results of the comet assay showed that all the organic concentrates from the water samples could induce different levels DNA damages on human peripheral blood lymphocytes, and a statistically significant difference (p&lt;0.01) was observed compared with the solvent control, which demonstrated the genotoxicity was in existence. According to the ambient severity (AS) of individual compound, we had sorted out the main organic pollutants in the drinking water source of the four waterworks, and the results showed that there was some potential hazard to human body for all the source water, namely the total ambient severity (TAS) of health for each water source was more than I. However, the TAS of ecology for each water source was less than 1, which indicated that it was safe to ecology. The results of this investigation demonstrate the application of the comet assay and the MEAS in aquatic environmental monitoring studies, and the comet assay found to be fast, sensitive, and suitable for genotoxicity monitoring programs of drinking water source. [Copyright &amp;y&amp; Elsevier]
– Name: AbstractSuppliedCopyright
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  Group: Ab
  Data: &lt;i&gt;Copyright of Journal of Environmental Sciences (Elsevier) is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1016/S1001-0742(06)60026-0
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        Text: English
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    Subjects:
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        Type: general
      – SubjectFull: Waste products
        Type: general
      – SubjectFull: Water supply
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      – SubjectFull: Genetic toxicology
        Type: general
    Titles:
      – TitleFull: Genotoxicity evaluation and a primary risk assessment of organic pollutants in the drinking water sources of Nanjing, China
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            NameFull: LI, Yi-qiang
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            NameFull: WU, Yu-lin
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            NameFull: CHEN, Yuan-gao
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            NameFull: KONG, Zhi-ming
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            – D: 01
              M: 09
              Text: Sep2006
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              Y: 2006
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