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Toxicity and physiological effects of brominated flame retardant PBDE-47 on two life stages of grass shrimp, Palaemonetes pugio

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Title: Toxicity and physiological effects of brominated flame retardant PBDE-47 on two life stages of grass shrimp, Palaemonetes pugio
Authors: Key, Peter B.1 pete.key@noaa.gov, Chung, Katy W.2, Hoguet, Jennifer2, Shaddrix, Brian2, Fulton, Michael H.1
Source: Science of the Total Environment. Jul2008, Vol. 399 Issue 1-3, p28-32. 5p.
Subjects: Shrimps, Polybrominated biphenyls, Biomarkers, Confidence intervals, Polybrominated diphenyl ethers, Environmental toxicology
Abstract: Abstract: This study examined the effects of a polybrominated diphenyl ether (PBDE) compound, PBDE-47, on adult and larval stages of the estuarine grass shrimp (Palaemonetes pugio). The 96-h LC50 test resulted in an estimate of 23.60 µg/L (95% confidence interval=14.51–38.37 µg/L) for larval shrimp. Adult shrimp had a higher 96-h LC50 of 78.07 µg/L (95% CI=65.1–93.63 µg/L). Four physiological biomarkers glutathione (GSH), lipid peroxidation (LPx), cholesterol (CHL) and acetylcholinesterase (AChE) were then assessed to study the sublethal effects of PBDE-47 exposure. GSH, LPx and AChE levels in both adults and larvae were not affected by PBDE-47 at concentrations up to 50 µg/L for 96 h. CHL levels were elevated in adults and larvae at the lowest exposure concentrations tested, but significant differences were found only in adult exposures. Effects associated with PBDE-47 aqueous exposures were observed at levels well above those reported in the environment. [Copyright &y& Elsevier]
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Database: Engineering Source
Description
Abstract:Abstract: This study examined the effects of a polybrominated diphenyl ether (PBDE) compound, PBDE-47, on adult and larval stages of the estuarine grass shrimp (Palaemonetes pugio). The 96-h LC50 test resulted in an estimate of 23.60 µg/L (95% confidence interval=14.51–38.37 µg/L) for larval shrimp. Adult shrimp had a higher 96-h LC50 of 78.07 µg/L (95% CI=65.1–93.63 µg/L). Four physiological biomarkers glutathione (GSH), lipid peroxidation (LPx), cholesterol (CHL) and acetylcholinesterase (AChE) were then assessed to study the sublethal effects of PBDE-47 exposure. GSH, LPx and AChE levels in both adults and larvae were not affected by PBDE-47 at concentrations up to 50 µg/L for 96 h. CHL levels were elevated in adults and larvae at the lowest exposure concentrations tested, but significant differences were found only in adult exposures. Effects associated with PBDE-47 aqueous exposures were observed at levels well above those reported in the environment. [Copyright &y& Elsevier]
ISSN:00489697
DOI:10.1016/j.scitotenv.2008.03.021