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A Strategy for the Solution-Phase Parallel Synthesis of N-(Pyrrolidinylmethyl)hydroxamic Acids.

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Title: A Strategy for the Solution-Phase Parallel Synthesis of N-(Pyrrolidinylmethyl)hydroxamic Acids.
Authors: Takayanagi, Masaru, Flessner, Timo
Source: Journal of Organic Chemistry. 06/16/2000, Vol. 65 Issue 12, p3811. 5p. 3 Diagrams, 1 Chart.
Subjects: Imino compounds, Cyclitols, Hydroxamic acids, Manganese, Biosynthesis
Abstract: Describes the development of a general strategy toward the parallel synthesis of a five-membered iminocyclitol linked to a hydroxamic acid group designed to mimic the transition state of GDP-fucose complexed with Mn(II) in fucosyltransferase reactions. Preparation of an iminocyclitol containing a protected hydroxylamine unit from D-mannitol.
Database: Engineering Source
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Header DbId: egs
DbLabel: Engineering Source
An: 3327842
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
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  Label: Title
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  Data: A Strategy for the Solution-Phase Parallel Synthesis of N-(Pyrrolidinylmethyl)hydroxamic Acids.
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  Data: <searchLink fieldCode="AR" term="%22Takayanagi%2C+Masaru%22">Takayanagi, Masaru</searchLink><br /><searchLink fieldCode="AR" term="%22Flessner%2C+Timo%22">Flessner, Timo</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Organic+Chemistry%22">Journal of Organic Chemistry</searchLink>. 06/16/2000, Vol. 65 Issue 12, p3811. 5p. 3 Diagrams, 1 Chart.
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  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22Imino+compounds%22">Imino compounds</searchLink><br /><searchLink fieldCode="DE" term="%22Cyclitols%22">Cyclitols</searchLink><br /><searchLink fieldCode="DE" term="%22Hydroxamic+acids%22">Hydroxamic acids</searchLink><br /><searchLink fieldCode="DE" term="%22Manganese%22">Manganese</searchLink><br /><searchLink fieldCode="DE" term="%22Biosynthesis%22">Biosynthesis</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Describes the development of a general strategy toward the parallel synthesis of a five-membered iminocyclitol linked to a hydroxamic acid group designed to mimic the transition state of GDP-fucose complexed with Mn(II) in fucosyltransferase reactions. Preparation of an iminocyclitol containing a protected hydroxylamine unit from D-mannitol.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=3327842
RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1021/jo000186k
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 5
        StartPage: 3811
    Subjects:
      – SubjectFull: Imino compounds
        Type: general
      – SubjectFull: Cyclitols
        Type: general
      – SubjectFull: Hydroxamic acids
        Type: general
      – SubjectFull: Manganese
        Type: general
      – SubjectFull: Biosynthesis
        Type: general
    Titles:
      – TitleFull: A Strategy for the Solution-Phase Parallel Synthesis of N-(Pyrrolidinylmethyl)hydroxamic Acids.
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            NameFull: Takayanagi, Masaru
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            NameFull: Flessner, Timo
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          Dates:
            – D: 16
              M: 06
              Text: 06/16/2000
              Type: published
              Y: 2000
          Identifiers:
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              Value: 00223263
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              Value: 65
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              Value: 12
          Titles:
            – TitleFull: Journal of Organic Chemistry
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