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Early Clinical Experience With Kilovoltage Image-Guided Radiation Therapy for Interfraction Motion Management

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Title: Early Clinical Experience With Kilovoltage Image-Guided Radiation Therapy for Interfraction Motion Management
Authors: Lawson, Joshua D. joshua@radonc.emory.org, Fox, Tim1, Elder, Eric1, Nowlan, Adam1, Davis, Lawrence1, Keller, James1, Crocker, Ian1
Source: Medical Dosimetry. Winter2008, Vol. 33 Issue 4, p268-274. 7p.
Subjects: Image-guided radiation therapy, Cancer treatment, Cancer patients, Medical imaging systems, Medical care
Abstract: Abstract: Interest in image-guided radiation therapy (IGRT) reflects the desire to minimize interfraction positioning variability. Using a kilovoltage (kV) imaging unit mounted to a traditional LINAC allows daily matching of kV images to planning digitally reconstructed radiographs (DRRs). We quantify and evaluate the significance of calculated deviation from the intended isocenter. Since September 2004, 117 patients with various malignancies were treated using the On-Board Imaging (OBI) system, with 2088 treatment sessions. Patients were positioned by the treating therapist; orthogonal images were then obtained with the OBI unit. Couch shifts were made, aligning bony anatomy to the initial simulation image. Routine port films were performed weekly (after that day''s OBI session). Ninety percent of all lateral, longitudinal, and vertical shifts were less than 0.8 cm, 0.6 cm, and 0.7 cm, respectively. The median vector shift for each anatomic site was: 0.42 cm for head and neck, 0.40 cm for CNS, 0.59 cm for GU/prostate, and 0.73 cm for breast; shift magnitude did not change with successive OBI sessions. The use of OBI effectively corrects setup variability. These shifts are typically small and random. The use of OBI likely can replace weekly port films for isocenter verification; however, OBI does not provide field shape verification. [Copyright &y& Elsevier]
Copyright of Medical Dosimetry is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 34996227
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Early Clinical Experience With Kilovoltage Image-Guided Radiation Therapy for Interfraction Motion Management
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  Data: <searchLink fieldCode="AR" term="%22Lawson%2C+Joshua+D%2E%22">Lawson, Joshua D.</searchLink><i> joshua@radonc.emory.org</i><br /><searchLink fieldCode="AR" term="%22Fox%2C+Tim%22">Fox, Tim</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Elder%2C+Eric%22">Elder, Eric</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Nowlan%2C+Adam%22">Nowlan, Adam</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Davis%2C+Lawrence%22">Davis, Lawrence</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Keller%2C+James%22">Keller, James</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Crocker%2C+Ian%22">Crocker, Ian</searchLink><relatesTo>1</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Medical+Dosimetry%22">Medical Dosimetry</searchLink>. Winter2008, Vol. 33 Issue 4, p268-274. 7p.
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  Data: <searchLink fieldCode="DE" term="%22Image-guided+radiation+therapy%22">Image-guided radiation therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+treatment%22">Cancer treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+patients%22">Cancer patients</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+imaging+systems%22">Medical imaging systems</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+care%22">Medical care</searchLink>
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  Data: Abstract: Interest in image-guided radiation therapy (IGRT) reflects the desire to minimize interfraction positioning variability. Using a kilovoltage (kV) imaging unit mounted to a traditional LINAC allows daily matching of kV images to planning digitally reconstructed radiographs (DRRs). We quantify and evaluate the significance of calculated deviation from the intended isocenter. Since September 2004, 117 patients with various malignancies were treated using the On-Board Imaging (OBI) system, with 2088 treatment sessions. Patients were positioned by the treating therapist; orthogonal images were then obtained with the OBI unit. Couch shifts were made, aligning bony anatomy to the initial simulation image. Routine port films were performed weekly (after that day''s OBI session). Ninety percent of all lateral, longitudinal, and vertical shifts were less than 0.8 cm, 0.6 cm, and 0.7 cm, respectively. The median vector shift for each anatomic site was: 0.42 cm for head and neck, 0.40 cm for CNS, 0.59 cm for GU/prostate, and 0.73 cm for breast; shift magnitude did not change with successive OBI sessions. The use of OBI effectively corrects setup variability. These shifts are typically small and random. The use of OBI likely can replace weekly port films for isocenter verification; however, OBI does not provide field shape verification. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Medical Dosimetry is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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