Bibliographic Details
| Title: |
A multi-agent model describing self-renewal of differentiation effects on the blood cell population |
| Authors: |
Bessonov, Nikolai1 nickbessonov@yahoo.com, Demin, Ivan2 demin@math.univ-lyon1.fr, Pujo-Menjouet, Laurent2 pujo@math.univ-lyon1.fr, Volpert, Vitaly2 volpert@math.univ-lyon1.fr |
| Source: |
Mathematical & Computer Modelling. Jun2009, Vol. 49 Issue 11/12, p2116-2127. 12p. |
| Subjects: |
Mathematical models, Cell differentiation, Blood cells, Cell populations, Mathematical models of population, Autopoiesis |
| Abstract: |
Abstract: In this work, a new multi-agent model is used to describe blood cell population dynamics. More particularly, we focus our simulations here on differentiation and self-renewal process based on cell communication. We consider the different cases where progenitor cells are able to self-renew or not in the bone marrow. As a consequence of this study, we give some possible explanations of the mechanism for recovery of the system under important blood loss or blood diseases such as anemia. [Copyright &y& Elsevier] |
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| Database: |
Engineering Source |
