First MR images obtained during megavoltage photon irradiation from a prototype integrated linac-MR system.
Saved in:
| Title: | First MR images obtained during megavoltage photon irradiation from a prototype integrated linac-MR system. |
|---|---|
| Authors: | Fallone, B. G.1,2 ginofall@cancerboard.ab.ca, Murray, B.1,2, Rathee, S.1,2, Stanescu, T.1, Steciw, S.1,2, Vidakovic, S.1,2, Blosser, E.1, Tymofichuk, D.1 |
| Source: | Medical Physics. Jun2009, Vol. 36 Issue 6, p2084-2088. 5p. 1 Color Photograph, 2 Black and White Photographs, 2 Diagrams, 3 Graphs. |
| Subjects: | Magnetic resonance imaging, Medical imaging systems, Radiotherapy, Radio frequency, Imaging phantoms |
| Abstract: | The authors report the first magnetic resonance (MR) images produced by their prototype MR system integrated with a radiation therapy source. The prototype consists of a 6 MV linac mounted onto the open end of a biplanar 0.2 T permanent MR system which has 27.9 cm pole-to-pole opening with flat gradients (40 mT/m) running under a TMX NRC console. The distance from the magnet isocenter to the linac target is 80 cm. The authors’ design has resolved the mutual interferences between the two devices such that the MR magnetic field does not interfere with the trajectory of the electron in the linac waveguide, and the radiofrequency (RF) signals from each system do not interfere with the operation of the other system. Magnetic and RF shielding calculations were performed and confirmed with appropriate measurements. The prototype is currently on a fixed gantry; however, in the very near future, the linac and MR magnet will rotate in unison such that the linac is always aimed through the opening in the biplanar magnet. MR imaging was found to be fully operational during linac irradiation and proven by imaging a phantom with conventional gradient echo sequences. Except for small changes in SNR, MR images produced during irradiation were visually and quantitatively very similar to those taken with the linac turned off. This prototype system provides proof of concept that the design has decreased the mutual interferences sufficiently to allow the development of real-time MR-guided radiotherapy. Low field-strength systems (0.2–0.5 T) have been used clinically as diagnostic tools. The task of the linac-MR system is, however, to provide MR guidance to the radiotherapy beam. Therefore, the 0.2 T field strength would provide adequate image quality for this purpose and, with the addition of fast imaging techniques, has the potential to provide 4D soft-tissue visualization not presently available in image-guided radiotherapy systems. The authors’ initial design incorporates a permanent magnet; however, other types of magnets and field strengths could also be incorporated. Usable MR images were obtained during linac irradiation from the linac-MR prototype. The authors’ prototype design can be used as the functional starting point in developing real-time MR guidance offering soft-tissue contrast that can be coupled with tumor tracking for real-time adaptive radiotherapy. [ABSTRACT FROM AUTHOR] |
| Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: egs DbLabel: Engineering Source An: 40418837 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: First MR images obtained during megavoltage photon irradiation from a prototype integrated linac-MR system. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Fallone%2C+B%2E+G%2E%22">Fallone, B. G.</searchLink><relatesTo>1,2</relatesTo><i> ginofall@cancerboard.ab.ca</i><br /><searchLink fieldCode="AR" term="%22Murray%2C+B%2E%22">Murray, B.</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Rathee%2C+S%2E%22">Rathee, S.</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Stanescu%2C+T%2E%22">Stanescu, T.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Steciw%2C+S%2E%22">Steciw, S.</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Vidakovic%2C+S%2E%22">Vidakovic, S.</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Blosser%2C+E%2E%22">Blosser, E.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Tymofichuk%2C+D%2E%22">Tymofichuk, D.</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Medical+Physics%22">Medical Physics</searchLink>. Jun2009, Vol. 36 Issue 6, p2084-2088. 5p. 1 Color Photograph, 2 Black and White Photographs, 2 Diagrams, 3 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+imaging+systems%22">Medical imaging systems</searchLink><br /><searchLink fieldCode="DE" term="%22Radiotherapy%22">Radiotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Radio+frequency%22">Radio frequency</searchLink><br /><searchLink fieldCode="DE" term="%22Imaging+phantoms%22">Imaging phantoms</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The authors report the first magnetic resonance (MR) images produced by their prototype MR system integrated with a radiation therapy source. The prototype consists of a 6 MV linac mounted onto the open end of a biplanar 0.2 T permanent MR system which has 27.9 cm pole-to-pole opening with flat gradients (40 mT/m) running under a TMX NRC console. The distance from the magnet isocenter to the linac target is 80 cm. The authors’ design has resolved the mutual interferences between the two devices such that the MR magnetic field does not interfere with the trajectory of the electron in the linac waveguide, and the radiofrequency (RF) signals from each system do not interfere with the operation of the other system. Magnetic and RF shielding calculations were performed and confirmed with appropriate measurements. The prototype is currently on a fixed gantry; however, in the very near future, the linac and MR magnet will rotate in unison such that the linac is always aimed through the opening in the biplanar magnet. MR imaging was found to be fully operational during linac irradiation and proven by imaging a phantom with conventional gradient echo sequences. Except for small changes in SNR, MR images produced during irradiation were visually and quantitatively very similar to those taken with the linac turned off. This prototype system provides proof of concept that the design has decreased the mutual interferences sufficiently to allow the development of real-time MR-guided radiotherapy. Low field-strength systems (0.2–0.5 T) have been used clinically as diagnostic tools. The task of the linac-MR system is, however, to provide MR guidance to the radiotherapy beam. Therefore, the 0.2 T field strength would provide adequate image quality for this purpose and, with the addition of fast imaging techniques, has the potential to provide 4D soft-tissue visualization not presently available in image-guided radiotherapy systems. The authors’ initial design incorporates a permanent magnet; however, other types of magnets and field strengths could also be incorporated. Usable MR images were obtained during linac irradiation from the linac-MR prototype. The authors’ prototype design can be used as the functional starting point in developing real-time MR guidance offering soft-tissue contrast that can be coupled with tumor tracking for real-time adaptive radiotherapy. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=40418837 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1118/1.3125662 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 2084 Subjects: – SubjectFull: Magnetic resonance imaging Type: general – SubjectFull: Medical imaging systems Type: general – SubjectFull: Radiotherapy Type: general – SubjectFull: Radio frequency Type: general – SubjectFull: Imaging phantoms Type: general Titles: – TitleFull: First MR images obtained during megavoltage photon irradiation from a prototype integrated linac-MR system. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fallone, B. G. – PersonEntity: Name: NameFull: Murray, B. – PersonEntity: Name: NameFull: Rathee, S. – PersonEntity: Name: NameFull: Stanescu, T. – PersonEntity: Name: NameFull: Steciw, S. – PersonEntity: Name: NameFull: Vidakovic, S. – PersonEntity: Name: NameFull: Blosser, E. – PersonEntity: Name: NameFull: Tymofichuk, D. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2009 Type: published Y: 2009 Identifiers: – Type: issn-print Value: 00942405 Numbering: – Type: volume Value: 36 – Type: issue Value: 6 Titles: – TitleFull: Medical Physics Type: main |
| ResultId | 1 |
