Estimating Need for Palliative External Beam Radiotherapy in Adult Cancer Patients

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Title: Estimating Need for Palliative External Beam Radiotherapy in Adult Cancer Patients
Authors: Nieder, Carsten1,2 carsten.nieder@nlsh.no, Pawinski, Adam1, Haukland, Ellinor1, Dokmo, Raymond1, Phillipi, Isabelle1, Dalhaug, Astrid1
Source: International Journal of Radiation Oncology, Biology, Physics. Jan2010, Vol. 76 Issue 1, p207-211. 5p.
Subjects: Palliative treatment, Cancer patients, Cancer radiotherapy, Palliative treatment of cancer, Metastasis, Radiosurgery, Confidence intervals, Socioeconomic factors
Abstract: Purpose: Older surveys and benchmark data from different sources have suggested that 46–53% of all radiotherapy courses were administered with palliative intent. In Sweden, 87 annual palliative treatment courses per 100,000 inhabitants were registered in 2001, mainly for the treatment of bone and brain metastases (95% confidence interval [CI] 85–89). The corresponding number for Norway was 95 (95% CI 93–98) in 2004. New data are lacking, although new systemic treatment options might alter this number. Methods and Materials: We collected prospective data on the use of palliative external beam radiotherapy for adult cancer patients during a 12-month period between 2007 and 2008. All patients (median age 69 years) were treated in one Norwegian county and had unlimited, rapid access to treatment. Efforts were made to account for potential overuse. Results: Most irradiated patients had skeletal target volumes, followed by nonbony thoracic targets and brain metastases. In the present population, 133 annual treatments per 100,000 inhabitants were registered (after correction for overuse, but not accounting for radiosurgery of brain metastases and emerging treatment options; e.g., stereotactic radiotherapy for lung and liver metastases; 95% CI 119–149). Because some patients received simultaneous treatment to different target volumes, the annual number of target volumes amounted to 175 per 100,000 inhabitants (95% CI 161–191). Conclusion: The need for palliative radiotherapy has not decreased and might be greater than previously estimated. In regions with a significantly different cancer incidence, age structure, and other socioeconomic factors than northern Europe, separate analyses should be conducted. [Copyright &y& Elsevier]
Copyright of International Journal of Radiation Oncology, Biology, Physics is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Estimating Need for Palliative External Beam Radiotherapy in Adult Cancer Patients
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  Data: <searchLink fieldCode="AR" term="%22Nieder%2C+Carsten%22">Nieder, Carsten</searchLink><relatesTo>1,2</relatesTo><i> carsten.nieder@nlsh.no</i><br /><searchLink fieldCode="AR" term="%22Pawinski%2C+Adam%22">Pawinski, Adam</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Haukland%2C+Ellinor%22">Haukland, Ellinor</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Dokmo%2C+Raymond%22">Dokmo, Raymond</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Phillipi%2C+Isabelle%22">Phillipi, Isabelle</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Dalhaug%2C+Astrid%22">Dalhaug, Astrid</searchLink><relatesTo>1</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Radiation+Oncology%2C+Biology%2C+Physics%22">International Journal of Radiation Oncology, Biology, Physics</searchLink>. Jan2010, Vol. 76 Issue 1, p207-211. 5p.
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  Data: <searchLink fieldCode="DE" term="%22Palliative+treatment%22">Palliative treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+patients%22">Cancer patients</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+radiotherapy%22">Cancer radiotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Palliative+treatment+of+cancer%22">Palliative treatment of cancer</searchLink><br /><searchLink fieldCode="DE" term="%22Metastasis%22">Metastasis</searchLink><br /><searchLink fieldCode="DE" term="%22Radiosurgery%22">Radiosurgery</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Socioeconomic+factors%22">Socioeconomic factors</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose: Older surveys and benchmark data from different sources have suggested that 46–53% of all radiotherapy courses were administered with palliative intent. In Sweden, 87 annual palliative treatment courses per 100,000 inhabitants were registered in 2001, mainly for the treatment of bone and brain metastases (95% confidence interval [CI] 85–89). The corresponding number for Norway was 95 (95% CI 93–98) in 2004. New data are lacking, although new systemic treatment options might alter this number. Methods and Materials: We collected prospective data on the use of palliative external beam radiotherapy for adult cancer patients during a 12-month period between 2007 and 2008. All patients (median age 69 years) were treated in one Norwegian county and had unlimited, rapid access to treatment. Efforts were made to account for potential overuse. Results: Most irradiated patients had skeletal target volumes, followed by nonbony thoracic targets and brain metastases. In the present population, 133 annual treatments per 100,000 inhabitants were registered (after correction for overuse, but not accounting for radiosurgery of brain metastases and emerging treatment options; e.g., stereotactic radiotherapy for lung and liver metastases; 95% CI 119–149). Because some patients received simultaneous treatment to different target volumes, the annual number of target volumes amounted to 175 per 100,000 inhabitants (95% CI 161–191). Conclusion: The need for palliative radiotherapy has not decreased and might be greater than previously estimated. In regions with a significantly different cancer incidence, age structure, and other socioeconomic factors than northern Europe, separate analyses should be conducted. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of International Journal of Radiation Oncology, Biology, Physics is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.ijrobp.2009.01.028
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      – Code: eng
        Text: English
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        PageCount: 5
        StartPage: 207
    Subjects:
      – SubjectFull: Palliative treatment
        Type: general
      – SubjectFull: Cancer patients
        Type: general
      – SubjectFull: Cancer radiotherapy
        Type: general
      – SubjectFull: Palliative treatment of cancer
        Type: general
      – SubjectFull: Metastasis
        Type: general
      – SubjectFull: Radiosurgery
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Socioeconomic factors
        Type: general
    Titles:
      – TitleFull: Estimating Need for Palliative External Beam Radiotherapy in Adult Cancer Patients
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            NameFull: Nieder, Carsten
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            NameFull: Dokmo, Raymond
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              Text: Jan2010
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              Y: 2010
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