Effective point of measurement of thimble ion chambers in megavoltage photon beams.

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Title: Effective point of measurement of thimble ion chambers in megavoltage photon beams.
Authors: Tessier, Frédéric1 frederic.tessier@nrc-cnrc.gc.ca, Kawrakow, Iwan1
Source: Medical Physics. Jan2010, Vol. 37 Issue 1, p96-107. 12p. 2 Charts, 8 Graphs.
Subjects: Drug dosage, Radiation dosimetry, Medical radiography, Scanning systems, Medical imaging systems
Abstract: Purpose: Determine the effective point of measurement (EPOM) of 12 thimble ion chambers, including miniature chambers and three models widely used for clinical reference dosimetry. The EPOM is the point at which the measured dose would arise in the measurement medium in the absence of the probe: For cylindrical chambers, it is shifted upstream relative to the central axis of the chamber. Although current dosimetry protocols prescribe a blanket upstream EPOM shift of 0.6r, with r as the chamber cavity radius, it has been shown in recent years that the EPOM does, in fact, depend on every detail of the chamber design and on the beam characteristics. In the wake of this finding, the authors undertake a comprehensive study of the EPOM for a series of chambers in water. Methods: This work relies on EGSnrc Monte Carlo calculations for the central axis depth dose in a water phantom and in ion chambers. They use a full Elekta Precise linac treatment head simulation to generate realistic photon beams with nominal energies of 6 and 25 MV and fields sizes of 10×10 and 40×40 cm2. The correct EPOM shift for the 12 ion chambers, modeled in realistic detail, is taken as the one minimizing the deviation of the ratio between the dose to water and the dose to the gas of the chamber cavity, according to a method proposed and validated in previous work. Results: The analysis reveals that the actual EPOM shift is significantly smaller than the recommended value in current dosimetry protocols, by up to 25% for reference-class chambers and 80% for miniature chambers. The location of the EPOM also depends on the characteristics of the incident beam and varies in a well-defined way with the cavity length, the central electrode radius, and the thimble wall thickness. Conclusions: The authors confirm that an upstream EPOM shift of 0.6r is too large for thimble ion chambers in high energy photon beams. Proper values for the EPOM shift could be tabulated per beam and per chamber, but they envisage that a single shift for all practical beams may prove sufficient. Moreover, the systematic dependence on chamber characteristics provides evidence that a universal parametrization in terms of a few design parameters is conceivable and has implication for the calculation of chamber correction factors. [ABSTRACT FROM AUTHOR]
Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Effective point of measurement of thimble ion chambers in megavoltage photon beams.
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  Data: <searchLink fieldCode="AR" term="%22Tessier%2C+Frédéric%22">Tessier, Frédéric</searchLink><relatesTo>1</relatesTo><i> frederic.tessier@nrc-cnrc.gc.ca</i><br /><searchLink fieldCode="AR" term="%22Kawrakow%2C+Iwan%22">Kawrakow, Iwan</searchLink><relatesTo>1</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Medical+Physics%22">Medical Physics</searchLink>. Jan2010, Vol. 37 Issue 1, p96-107. 12p. 2 Charts, 8 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Drug+dosage%22">Drug dosage</searchLink><br /><searchLink fieldCode="DE" term="%22Radiation+dosimetry%22">Radiation dosimetry</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+radiography%22">Medical radiography</searchLink><br /><searchLink fieldCode="DE" term="%22Scanning+systems%22">Scanning systems</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+imaging+systems%22">Medical imaging systems</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose: Determine the effective point of measurement (EPOM) of 12 thimble ion chambers, including miniature chambers and three models widely used for clinical reference dosimetry. The EPOM is the point at which the measured dose would arise in the measurement medium in the absence of the probe: For cylindrical chambers, it is shifted upstream relative to the central axis of the chamber. Although current dosimetry protocols prescribe a blanket upstream EPOM shift of 0.6r, with r as the chamber cavity radius, it has been shown in recent years that the EPOM does, in fact, depend on every detail of the chamber design and on the beam characteristics. In the wake of this finding, the authors undertake a comprehensive study of the EPOM for a series of chambers in water. Methods: This work relies on EGSnrc Monte Carlo calculations for the central axis depth dose in a water phantom and in ion chambers. They use a full Elekta Precise linac treatment head simulation to generate realistic photon beams with nominal energies of 6 and 25 MV and fields sizes of 10×10 and 40×40 cm2. The correct EPOM shift for the 12 ion chambers, modeled in realistic detail, is taken as the one minimizing the deviation of the ratio between the dose to water and the dose to the gas of the chamber cavity, according to a method proposed and validated in previous work. Results: The analysis reveals that the actual EPOM shift is significantly smaller than the recommended value in current dosimetry protocols, by up to 25% for reference-class chambers and 80% for miniature chambers. The location of the EPOM also depends on the characteristics of the incident beam and varies in a well-defined way with the cavity length, the central electrode radius, and the thimble wall thickness. Conclusions: The authors confirm that an upstream EPOM shift of 0.6r is too large for thimble ion chambers in high energy photon beams. Proper values for the EPOM shift could be tabulated per beam and per chamber, but they envisage that a single shift for all practical beams may prove sufficient. Moreover, the systematic dependence on chamber characteristics provides evidence that a universal parametrization in terms of a few design parameters is conceivable and has implication for the calculation of chamber correction factors. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1118/1.3266750
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        Text: English
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      – SubjectFull: Medical radiography
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      – SubjectFull: Scanning systems
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      – SubjectFull: Medical imaging systems
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      – TitleFull: Effective point of measurement of thimble ion chambers in megavoltage photon beams.
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              Text: Jan2010
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              Y: 2010
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