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Measurement of Aortic Intimal-Medial Thickness in Adolescents and Young Adults

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Title: Measurement of Aortic Intimal-Medial Thickness in Adolescents and Young Adults
Authors: Davis, Patricia H.1 pat-davis@uiowa.edu, Dawson, Jeffrey D.2, Blecha, M. Beth1, Mastbergen, Rebecca K.2, Sonka, Milan3
Source: Ultrasound in Medicine & Biology. Apr2010, Vol. 36 Issue 4, p560-565. 6p.
Subjects: Atherosclerosis, Abdominal aorta radiography, Thickness measurement, Ultrasonic imaging, Carotid artery, Diseases in young adults, Ultrasonic imaging of blood-vessels, Aorta, Research evaluation, Research funding, Smooth muscle
Abstract: Abstract: Atherosclerosis begins in childhood in the distal abdominal aorta and later involves the carotid arteries. Noninvasive screening to detect these lesions may allow early intervention. Ultrasound images of the distal 10 mm of the aorta were obtained after an 8-h fast and were analyzed by an automated program to determine the mean far wall intimal-medial thickness (IMT). The results were compared with the mean carotid IMT obtained concurrently. The mean age of the 313 males and 322 females imaged was 20.4 years (SD 5.6) and 61 participants had a second study to assess reproducibility. The mean aortic IMT was 0.63 mm (SD 0.14) for males and 0.61 mm (SD 0.13) for females while the mean carotid IMT was 0.50 (SD 0.04) mm and 0.49 (SD 0.04) mm, respectively. Images were analyzed in 95% of participants. Intra-subject reproducibility for the mean aortic IMT had a coefficient of variation of 18% with a mean absolute difference of 0.12 mm (SD 0.10). For carotid IMT, the results were 3% and 0.02 mm (SD 0.01), respectively. Aortic IMT can be measured in normal adolescents and young adults with low rates of missing data and reasonable reproducibility. Aortic IMT increased with age at a greater rate than carotid IMT. (E-mail: pat-davis@uiowa.edu) [Copyright &y& Elsevier]
Copyright of Ultrasound in Medicine & Biology is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
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PubType: Academic Journal
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  Data: Measurement of Aortic Intimal-Medial Thickness in Adolescents and Young Adults
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  Data: <searchLink fieldCode="AR" term="%22Davis%2C+Patricia+H%2E%22">Davis, Patricia H.</searchLink><relatesTo>1</relatesTo><i> pat-davis@uiowa.edu</i><br /><searchLink fieldCode="AR" term="%22Dawson%2C+Jeffrey+D%2E%22">Dawson, Jeffrey D.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Blecha%2C+M%2E+Beth%22">Blecha, M. Beth</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Mastbergen%2C+Rebecca+K%2E%22">Mastbergen, Rebecca K.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Sonka%2C+Milan%22">Sonka, Milan</searchLink><relatesTo>3</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Ultrasound+in+Medicine+%26+Biology%22">Ultrasound in Medicine & Biology</searchLink>. Apr2010, Vol. 36 Issue 4, p560-565. 6p.
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  Data: <searchLink fieldCode="DE" term="%22Atherosclerosis%22">Atherosclerosis</searchLink><br /><searchLink fieldCode="DE" term="%22Abdominal+aorta+radiography%22">Abdominal aorta radiography</searchLink><br /><searchLink fieldCode="DE" term="%22Thickness+measurement%22">Thickness measurement</searchLink><br /><searchLink fieldCode="DE" term="%22Ultrasonic+imaging%22">Ultrasonic imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Carotid+artery%22">Carotid artery</searchLink><br /><searchLink fieldCode="DE" term="%22Diseases+in+young+adults%22">Diseases in young adults</searchLink><br /><searchLink fieldCode="DE" term="%22Ultrasonic+imaging+of+blood-vessels%22">Ultrasonic imaging of blood-vessels</searchLink><br /><searchLink fieldCode="DE" term="%22Aorta%22">Aorta</searchLink><br /><searchLink fieldCode="DE" term="%22Research+evaluation%22">Research evaluation</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Smooth+muscle%22">Smooth muscle</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Abstract: Atherosclerosis begins in childhood in the distal abdominal aorta and later involves the carotid arteries. Noninvasive screening to detect these lesions may allow early intervention. Ultrasound images of the distal 10 mm of the aorta were obtained after an 8-h fast and were analyzed by an automated program to determine the mean far wall intimal-medial thickness (IMT). The results were compared with the mean carotid IMT obtained concurrently. The mean age of the 313 males and 322 females imaged was 20.4 years (SD 5.6) and 61 participants had a second study to assess reproducibility. The mean aortic IMT was 0.63 mm (SD 0.14) for males and 0.61 mm (SD 0.13) for females while the mean carotid IMT was 0.50 (SD 0.04) mm and 0.49 (SD 0.04) mm, respectively. Images were analyzed in 95% of participants. Intra-subject reproducibility for the mean aortic IMT had a coefficient of variation of 18% with a mean absolute difference of 0.12 mm (SD 0.10). For carotid IMT, the results were 3% and 0.02 mm (SD 0.01), respectively. Aortic IMT can be measured in normal adolescents and young adults with low rates of missing data and reasonable reproducibility. Aortic IMT increased with age at a greater rate than carotid IMT. (E-mail: pat-davis@uiowa.edu) [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Ultrasound in Medicine & Biology is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.ultrasmedbio.2010.01.002
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      – Code: eng
        Text: English
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    Subjects:
      – SubjectFull: Atherosclerosis
        Type: general
      – SubjectFull: Abdominal aorta radiography
        Type: general
      – SubjectFull: Thickness measurement
        Type: general
      – SubjectFull: Ultrasonic imaging
        Type: general
      – SubjectFull: Carotid artery
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      – SubjectFull: Diseases in young adults
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      – SubjectFull: Ultrasonic imaging of blood-vessels
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      – SubjectFull: Aorta
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      – SubjectFull: Research evaluation
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      – SubjectFull: Research funding
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      – SubjectFull: Smooth muscle
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    Titles:
      – TitleFull: Measurement of Aortic Intimal-Medial Thickness in Adolescents and Young Adults
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            NameFull: Davis, Patricia H.
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              M: 04
              Text: Apr2010
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              Y: 2010
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