Improving polyp detection algorithms for CT colonography: Pareto front approach

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Title: Improving polyp detection algorithms for CT colonography: Pareto front approach
Authors: Huang, Adam1,2, Li, Jiang1,3, Summers, Ronald M.1, Petrick, Nicholas4, Hara, Amy K.5
Source: Pattern Recognition Letters. Aug2010, Vol. 31 Issue 11, p1461-1469. 9p.
Subjects: POLYP (Computer system), Algorithms, Virtual colonoscopy, Performance evaluation, Pareto optimum, Evolutionary computation, Sensitivity analysis
Abstract: Abstract: We investigated a Pareto front approach to improve polyp detection algorithms for CT colonography (CTC). A dataset of 56 CTC colon surfaces with 87 proven positive detections of 53 polyps sized 4–60mm was used to evaluate the performance of a one-step and a two-step curvature-based region growing algorithm. The algorithmic performance was statistically evaluated and compared based on the Pareto optimal solutions from 20 experiments by evolutionary algorithms. The false positive rate was lower (p <0.05) by the two-step algorithm than by the one-step for 63% of all possible operating points. While operating at a suitable sensitivity level such as 90.8% (79/87) or 88.5% (77/87), the false positive rate was reduced by 24.4% (95% confidence intervals 17.9–31.0%) or 45.8% (95% confidence intervals 40.1–51.0%), respectively. We demonstrated that, with a proper experimental design, the Pareto optimization process can effectively help in fine-tuning and redesigning polyp detection algorithms. [Copyright &y& Elsevier]
Copyright of Pattern Recognition Letters is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Abstract: We investigated a Pareto front approach to improve polyp detection algorithms for CT colonography (CTC). A dataset of 56 CTC colon surfaces with 87 proven positive detections of 53 polyps sized 4–60mm was used to evaluate the performance of a one-step and a two-step curvature-based region growing algorithm. The algorithmic performance was statistically evaluated and compared based on the Pareto optimal solutions from 20 experiments by evolutionary algorithms. The false positive rate was lower (p &lt;0.05) by the two-step algorithm than by the one-step for 63% of all possible operating points. While operating at a suitable sensitivity level such as 90.8% (79/87) or 88.5% (77/87), the false positive rate was reduced by 24.4% (95% confidence intervals 17.9–31.0%) or 45.8% (95% confidence intervals 40.1–51.0%), respectively. We demonstrated that, with a proper experimental design, the Pareto optimization process can effectively help in fine-tuning and redesigning polyp detection algorithms. [Copyright &amp;y&amp; Elsevier]
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  Data: &lt;i&gt;Copyright of Pattern Recognition Letters is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.patrec.2010.03.013
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 9
        StartPage: 1461
    Subjects:
      – SubjectFull: POLYP (Computer system)
        Type: general
      – SubjectFull: Algorithms
        Type: general
      – SubjectFull: Virtual colonoscopy
        Type: general
      – SubjectFull: Performance evaluation
        Type: general
      – SubjectFull: Pareto optimum
        Type: general
      – SubjectFull: Evolutionary computation
        Type: general
      – SubjectFull: Sensitivity analysis
        Type: general
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      – TitleFull: Improving polyp detection algorithms for CT colonography: Pareto front approach
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            NameFull: Huang, Adam
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            NameFull: Li, Jiang
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            NameFull: Summers, Ronald M.
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              M: 08
              Text: Aug2010
              Type: published
              Y: 2010
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              Value: 31
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