Unexpected sudden death due to intracranial chordoma: An autopsy case
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| Title: | Unexpected sudden death due to intracranial chordoma: An autopsy case |
|---|---|
| Authors: | Li, Dong-Ri1,2 m1266285@med.osaka-cu.ac.jp, Ishikawa, Takaki1,3, Zhao, Dong1, Michiue, Tomomi1,3, Quan, Li1, Zhu, Bao-Li1,4, Maeda, Hitoshi1,3 |
| Source: | Forensic Science International. Jul2010, Vol. 200 Issue 1-3, pe15-e18. 0p. |
| Subjects: | Sudden death, Chordoma, Autopsy, Forensic pathology, Hydrocephalus, Forensic sciences, Forensic medicine, Intracranial tumors |
| Abstract: | Abstract: Intracranial chordoma is a locally invasive, relatively rare tumour at the base of the skull. The tumour usually grows slowly but there have been several case reports of sudden death, all of which were due to tumour-associated haemorrhages. We report an autopsy case of a sudden unexpected death due to clinically undiagnosed intracranial chordoma in the brainstem without haemorrhage. A 44-year-old man was found dead at home. The autopsy revealed two small gelatinous and semi-translucent greyish tumours on the ventral surface of the brainstem between the midbrain and pons. The tumours were not attached to the dura or bone. The brain was markedly swollen, with enlarged lateral and third ventricles, but the aqueduct was compressed and narrowed. Microscopically, the tumour invaded the cerebral peduncles, and was classified as a chordoma. The cause of death was diagnosed as acute obstructive hydrocephalus due to a ventral brainstem tumour. Even a minor intracranial tumour that is not primarily life-threatening may cause sudden death due to subsequent obstructive hydrocephalus. The brainstem is one of the most vulnerable regions in the brain, and careful examination of this region is important for forensic pathologists. [Copyright &y& Elsevier] |
| Copyright of Forensic Science International is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 51845055 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Unexpected sudden death due to intracranial chordoma: An autopsy case – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Li%2C+Dong-Ri%22">Li, Dong-Ri</searchLink><relatesTo>1,2</relatesTo><i> m1266285@med.osaka-cu.ac.jp</i><br /><searchLink fieldCode="AR" term="%22Ishikawa%2C+Takaki%22">Ishikawa, Takaki</searchLink><relatesTo>1,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhao%2C+Dong%22">Zhao, Dong</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Michiue%2C+Tomomi%22">Michiue, Tomomi</searchLink><relatesTo>1,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Quan%2C+Li%22">Quan, Li</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhu%2C+Bao-Li%22">Zhu, Bao-Li</searchLink><relatesTo>1,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Maeda%2C+Hitoshi%22">Maeda, Hitoshi</searchLink><relatesTo>1,3</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Forensic+Science+International%22">Forensic Science International</searchLink>. Jul2010, Vol. 200 Issue 1-3, pe15-e18. 0p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Sudden+death%22">Sudden death</searchLink><br /><searchLink fieldCode="DE" term="%22Chordoma%22">Chordoma</searchLink><br /><searchLink fieldCode="DE" term="%22Autopsy%22">Autopsy</searchLink><br /><searchLink fieldCode="DE" term="%22Forensic+pathology%22">Forensic pathology</searchLink><br /><searchLink fieldCode="DE" term="%22Hydrocephalus%22">Hydrocephalus</searchLink><br /><searchLink fieldCode="DE" term="%22Forensic+sciences%22">Forensic sciences</searchLink><br /><searchLink fieldCode="DE" term="%22Forensic+medicine%22">Forensic medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Intracranial+tumors%22">Intracranial tumors</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Abstract: Intracranial chordoma is a locally invasive, relatively rare tumour at the base of the skull. The tumour usually grows slowly but there have been several case reports of sudden death, all of which were due to tumour-associated haemorrhages. We report an autopsy case of a sudden unexpected death due to clinically undiagnosed intracranial chordoma in the brainstem without haemorrhage. A 44-year-old man was found dead at home. The autopsy revealed two small gelatinous and semi-translucent greyish tumours on the ventral surface of the brainstem between the midbrain and pons. The tumours were not attached to the dura or bone. The brain was markedly swollen, with enlarged lateral and third ventricles, but the aqueduct was compressed and narrowed. Microscopically, the tumour invaded the cerebral peduncles, and was classified as a chordoma. The cause of death was diagnosed as acute obstructive hydrocephalus due to a ventral brainstem tumour. Even a minor intracranial tumour that is not primarily life-threatening may cause sudden death due to subsequent obstructive hydrocephalus. The brainstem is one of the most vulnerable regions in the brain, and careful examination of this region is important for forensic pathologists. [Copyright &y& Elsevier] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Forensic Science International is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.forsciint.2010.03.037 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 0 StartPage: e15 Subjects: – SubjectFull: Sudden death Type: general – SubjectFull: Chordoma Type: general – SubjectFull: Autopsy Type: general – SubjectFull: Forensic pathology Type: general – SubjectFull: Hydrocephalus Type: general – SubjectFull: Forensic sciences Type: general – SubjectFull: Forensic medicine Type: general – SubjectFull: Intracranial tumors Type: general Titles: – TitleFull: Unexpected sudden death due to intracranial chordoma: An autopsy case Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Li, Dong-Ri – PersonEntity: Name: NameFull: Ishikawa, Takaki – PersonEntity: Name: NameFull: Zhao, Dong – PersonEntity: Name: NameFull: Michiue, Tomomi – PersonEntity: Name: NameFull: Quan, Li – PersonEntity: Name: NameFull: Zhu, Bao-Li – PersonEntity: Name: NameFull: Maeda, Hitoshi IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 07 Text: Jul2010 Type: published Y: 2010 Identifiers: – Type: issn-print Value: 03790738 Numbering: – Type: volume Value: 200 – Type: issue Value: 1-3 Titles: – TitleFull: Forensic Science International Type: main |
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