Assessment of variation in Elekta® plastic spherical-calibration phantom and its impact on the Leksell Gamma Knife® calibration.

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Title: Assessment of variation in Elekta® plastic spherical-calibration phantom and its impact on the Leksell Gamma Knife® calibration.
Authors: Novotny, Jr., Josef1 novotnyj@upmc.edu, Bhatnagar, Jagdish P.1, Hyun-Tai Chung2, Johansson, Jonas3, Bednarz, Greg1, Lijun Ma4, Huq, M. Saiful1
Source: Medical Physics. Sep2010, Vol. 37 Issue 9, p5066-5071. 6p. 1 Black and White Photograph, 2 Charts, 1 Graph.
Subjects: Imaging phantoms, Body composition models, Methodology, Irradiation, Mathematical models
Abstract: Purpose: Traditionally, the dose-rate calibration (output) of the Leksell Gamma Knife® (LGK) unit is performed using a 160 mm diameter plastic spherical phantom provided by the vendor of the LGK, Elekta Instrument AB. The purpose of this study was to evaluate variations in the Elekta spherical phantom and to assess its impact and use for the LGK calibration. Methods: Altogether, 13 phantoms from six different centers were acquired, 10 of these phantoms were manufactured within the past 10 years and the last 3 approximately 15–20 years ago. To assess variation in phantoms, the diameter and mass densities were measured. To assess the impact on LGK calibration, the output of two models of LGK (LGK Perfexion™ and LGK 4C) were measured under identical irradiation conditions using all 13 phantoms for each LGK model. Results: The mean measured deviation in diameter from expected nominal 160 mm for 13 phantoms was 0.51 mm (range of 0.09–1.51 mm). The mean measured phantom mass density for 13 phantoms was 1.066±0.019 g/cm3 (range of 1.046–1.102 g/cm3). The percentage deviation of output for individual phantom from mean of 13 phantom outputs ranged from -0.37% to 0.55% for LGK Perfexion™. Similarly, the percentage deviation of output for individual phantom from mean of 13 phantom outputs ranged from -0.72% to 0.47% for LGK 4C. Conclusions: This study demonstrated that small variations in terms of phantom size and mass density of the phantom material do not have a significant impact on dose-rate measurements of the Leksell Gamma Knife®. Also, date of manufacture of the phantom did not show up to be a significant factor in this study. [ABSTRACT FROM AUTHOR]
Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Assessment of variation in Elekta® plastic spherical-calibration phantom and its impact on the Leksell Gamma Knife® calibration.
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  Data: <searchLink fieldCode="JN" term="%22Medical+Physics%22">Medical Physics</searchLink>. Sep2010, Vol. 37 Issue 9, p5066-5071. 6p. 1 Black and White Photograph, 2 Charts, 1 Graph.
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  Data: Purpose: Traditionally, the dose-rate calibration (output) of the Leksell Gamma Knife® (LGK) unit is performed using a 160 mm diameter plastic spherical phantom provided by the vendor of the LGK, Elekta Instrument AB. The purpose of this study was to evaluate variations in the Elekta spherical phantom and to assess its impact and use for the LGK calibration. Methods: Altogether, 13 phantoms from six different centers were acquired, 10 of these phantoms were manufactured within the past 10 years and the last 3 approximately 15–20 years ago. To assess variation in phantoms, the diameter and mass densities were measured. To assess the impact on LGK calibration, the output of two models of LGK (LGK Perfexion™ and LGK 4C) were measured under identical irradiation conditions using all 13 phantoms for each LGK model. Results: The mean measured deviation in diameter from expected nominal 160 mm for 13 phantoms was 0.51 mm (range of 0.09–1.51 mm). The mean measured phantom mass density for 13 phantoms was 1.066±0.019 g/cm3 (range of 1.046–1.102 g/cm3). The percentage deviation of output for individual phantom from mean of 13 phantom outputs ranged from -0.37% to 0.55% for LGK Perfexion™. Similarly, the percentage deviation of output for individual phantom from mean of 13 phantom outputs ranged from -0.72% to 0.47% for LGK 4C. Conclusions: This study demonstrated that small variations in terms of phantom size and mass density of the phantom material do not have a significant impact on dose-rate measurements of the Leksell Gamma Knife®. Also, date of manufacture of the phantom did not show up to be a significant factor in this study. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: Sep2010
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