4D XCAT phantom for multimodality imaging research.
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| Title: | 4D XCAT phantom for multimodality imaging research. |
|---|---|
| Authors: | Segars, W. P.1 paul.segars@duke.ed, Sturgeon, G.1,2, Mendonca, S.1, Grimes, Jason1, Tsui, B. M. W.3 |
| Source: | Medical Physics. Sep2010, Vol. 37 Issue 9, p4902-4915. 14p. 9 Color Photographs, 3 Black and White Photographs, 5 Charts, 2 Graphs. |
| Subjects: | Imaging phantoms, Body composition models, Imaging systems, Human biology, Simulation methods & models |
| Abstract: | Purpose: The authors develop the 4D extended cardiac-torso (XCAT) phantom for multimodality imaging research. Methods: Highly detailed whole-body anatomies for the adult male and female were defined in the XCAT using nonuniform rational B-spline (NURBS) and subdivision surfaces based on segmentation of the Visible Male and Female anatomical datasets from the National Library of Medicine as well as patient datasets. Using the flexibility of these surfaces, the Visible Human anatomies were transformed to match body measurements and organ volumes for a 50th percentile (height and weight) male and female. The desired body measurements for the models were obtained using the PEOPLESIZE program that contains anthropometric dimensions categorized from 1st to the 99th percentile for US adults. The desired organ volumes were determined from ICRP Publication 89 [ICRP, ‘‘Basic anatomical and physiological data for use in radiological protection: reference values,” ICRP Publication 89 (International Commission on Radiological Protection, New York, NY, 2002)]. The male and female anatomies serve as standard templates upon which anatomical variations may be modeled in the XCAT through user-defined parameters. Parametrized models for the cardiac and respiratory motions were also incorporated into the XCAT based on high-resolution cardiac- and respiratory-gated multislice CT data. To demonstrate the usefulness of the phantom, the authors show example simulation studies in PET, SPECT, and CT using publicly available simulation packages. Results: As demonstrated in the pilot studies, the 4D XCAT (which includes thousands of anatomical structures) can produce realistic imaging data when combined with accurate models of the imaging process. With the flexibility of the NURBS surface primitives, any number of different anatomies, cardiac or respiratory motions or patterns, and spatial resolutions can be simulated to perform imaging research. Conclusions: With the ability to produce realistic, predictive 3D and 4D imaging data from populations of normal and abnormal patients under various imaging parameters, the authors conclude that the XCAT provides an important tool in imaging research to evaluate and improve imaging devices and techniques. In the field of x-ray CT, the phantom may also provide the necessary foundation with which to optimize clinical CT applications in terms of image quality versus radiation dose, an area of research that is becoming more significant with the growing use of CT. [ABSTRACT FROM AUTHOR] |
| Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 53422123 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: 4D XCAT phantom for multimodality imaging research. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Segars%2C+W%2E+P%2E%22">Segars, W. P.</searchLink><relatesTo>1</relatesTo><i> paul.segars@duke.ed</i><br /><searchLink fieldCode="AR" term="%22Sturgeon%2C+G%2E%22">Sturgeon, G.</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Mendonca%2C+S%2E%22">Mendonca, S.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Grimes%2C+Jason%22">Grimes, Jason</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Tsui%2C+B%2E+M%2E+W%2E%22">Tsui, B. M. W.</searchLink><relatesTo>3</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Medical+Physics%22">Medical Physics</searchLink>. Sep2010, Vol. 37 Issue 9, p4902-4915. 14p. 9 Color Photographs, 3 Black and White Photographs, 5 Charts, 2 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Imaging+phantoms%22">Imaging phantoms</searchLink><br /><searchLink fieldCode="DE" term="%22Body+composition+models%22">Body composition models</searchLink><br /><searchLink fieldCode="DE" term="%22Imaging+systems%22">Imaging systems</searchLink><br /><searchLink fieldCode="DE" term="%22Human+biology%22">Human biology</searchLink><br /><searchLink fieldCode="DE" term="%22Simulation+methods+%26+models%22">Simulation methods & models</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: The authors develop the 4D extended cardiac-torso (XCAT) phantom for multimodality imaging research. Methods: Highly detailed whole-body anatomies for the adult male and female were defined in the XCAT using nonuniform rational B-spline (NURBS) and subdivision surfaces based on segmentation of the Visible Male and Female anatomical datasets from the National Library of Medicine as well as patient datasets. Using the flexibility of these surfaces, the Visible Human anatomies were transformed to match body measurements and organ volumes for a 50th percentile (height and weight) male and female. The desired body measurements for the models were obtained using the PEOPLESIZE program that contains anthropometric dimensions categorized from 1st to the 99th percentile for US adults. The desired organ volumes were determined from ICRP Publication 89 [ICRP, ‘‘Basic anatomical and physiological data for use in radiological protection: reference values,” ICRP Publication 89 (International Commission on Radiological Protection, New York, NY, 2002)]. The male and female anatomies serve as standard templates upon which anatomical variations may be modeled in the XCAT through user-defined parameters. Parametrized models for the cardiac and respiratory motions were also incorporated into the XCAT based on high-resolution cardiac- and respiratory-gated multislice CT data. To demonstrate the usefulness of the phantom, the authors show example simulation studies in PET, SPECT, and CT using publicly available simulation packages. Results: As demonstrated in the pilot studies, the 4D XCAT (which includes thousands of anatomical structures) can produce realistic imaging data when combined with accurate models of the imaging process. With the flexibility of the NURBS surface primitives, any number of different anatomies, cardiac or respiratory motions or patterns, and spatial resolutions can be simulated to perform imaging research. Conclusions: With the ability to produce realistic, predictive 3D and 4D imaging data from populations of normal and abnormal patients under various imaging parameters, the authors conclude that the XCAT provides an important tool in imaging research to evaluate and improve imaging devices and techniques. In the field of x-ray CT, the phantom may also provide the necessary foundation with which to optimize clinical CT applications in terms of image quality versus radiation dose, an area of research that is becoming more significant with the growing use of CT. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1118/1.3480985 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 14 StartPage: 4902 Subjects: – SubjectFull: Imaging phantoms Type: general – SubjectFull: Body composition models Type: general – SubjectFull: Imaging systems Type: general – SubjectFull: Human biology Type: general – SubjectFull: Simulation methods & models Type: general Titles: – TitleFull: 4D XCAT phantom for multimodality imaging research. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Segars, W. P. – PersonEntity: Name: NameFull: Sturgeon, G. – PersonEntity: Name: NameFull: Mendonca, S. – PersonEntity: Name: NameFull: Grimes, Jason – PersonEntity: Name: NameFull: Tsui, B. M. W. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: Sep2010 Type: published Y: 2010 Identifiers: – Type: issn-print Value: 00942405 Numbering: – Type: volume Value: 37 – Type: issue Value: 9 Titles: – TitleFull: Medical Physics Type: main |
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