Bibliographic Details
| Title: |
Synthesis and Comparative Study on the Reactivity of Peptidyl-Type Phosphinic Esters.... |
| Authors: |
Georgiadis, Dimitris, Dive, Vincent, Yiotakis, Athanasios |
| Source: |
Journal of Organic Chemistry. 10/5/2001, Vol. 66 Issue 20, p6604. 7p. 6 Diagrams, 4 Charts. |
| Subjects: |
Esters, Phosphine, Reactivity (Chemistry) |
| Abstract: |
Examines the reactivity of peptidyl-type phosphinic esters under conventional deprotection conditions. Use of the phosphinic analogue of Cbz-Phe-Gly-OEt as a template; Effect of ateric hindrance on the rate of hydrolysis of beta-carboxyphosphinates; Factors affecting the occurrence of the acceleration of phosphinate cleavage. |
| Database: |
Engineering Source |
