Fracture toughness and compressive properties of cancellous bone at the head of the femur and relationships to non-invasive skeletal assessment measurements
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| Title: | Fracture toughness and compressive properties of cancellous bone at the head of the femur and relationships to non-invasive skeletal assessment measurements |
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| Authors: | Cook, R.B.1, Curwen, C.2, Tasker, T.2, Zioupos, P.3 p.zioupos@cranfield.ac.uk |
| Source: | Medical Engineering & Physics. Nov2010, Vol. 32 Issue 9, p991-997. 7p. |
| Subjects: | Osteoporosis, Femur head, Bone mechanics, Bone density, Risk factors of fractures, Femur neck, Ultrasonic imaging, Surgery |
| Abstract: | Abstract: Osteoporosis defines a causal relationship between reduced bone density, reduced mechanical competence of the bone tissue of the sufferers and concomitantly an increased risk of fracture in life. The aims of the present study is: (1) to provide further evidence to support the use of Quantitative Ultrasound (QUS) results from peripheral sites to provide a prediction of the density of the proximal femur; and (2) to provide rational evidence for the well-proven ability of QUS to predict directly ‘risk of fracture’. 20 femoral heads were obtained from 15 Caucasian females and 5 Caucasian males undergoing emergency surgery for a fractured neck of femur. QUS investigations of the calcaneus, proximal phalanx, distal radius and mid-shaft tibia were undertaken on the donors with 72h of surgery. 128 fracture toughness samples and 20 compression cores were manufactured and tested. Significant relationships were found between QUS parameters determined in vivo and the apparent density (g/cm3) of the tissue at the proximal femur and both the fracture toughness and strength determined in vitro from the same donor individual. In this study we relate QUS results obtained in vivo to the actual apparent density of bone tissue from the proximal femur, donated by the same individual, and the fracture toughness and compressive strength. The study demonstrates the ability of QUS investigations at peripheral sites to accurately predict the density of bone from the proximal femur and provides evidence to support the use of QUS to predict the ‘risk of fracture’ directly. [ABSTRACT FROM AUTHOR] |
| Copyright of Medical Engineering & Physics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 54882058 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Fracture toughness and compressive properties of cancellous bone at the head of the femur and relationships to non-invasive skeletal assessment measurements – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Cook%2C+R%2EB%2E%22">Cook, R.B.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Curwen%2C+C%2E%22">Curwen, C.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Tasker%2C+T%2E%22">Tasker, T.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Zioupos%2C+P%2E%22">Zioupos, P.</searchLink><relatesTo>3</relatesTo><i> p.zioupos@cranfield.ac.uk</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Medical+Engineering+%26+Physics%22">Medical Engineering & Physics</searchLink>. Nov2010, Vol. 32 Issue 9, p991-997. 7p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Osteoporosis%22">Osteoporosis</searchLink><br /><searchLink fieldCode="DE" term="%22Femur+head%22">Femur head</searchLink><br /><searchLink fieldCode="DE" term="%22Bone+mechanics%22">Bone mechanics</searchLink><br /><searchLink fieldCode="DE" term="%22Bone+density%22">Bone density</searchLink><br /><searchLink fieldCode="DE" term="%22Risk+factors+of+fractures%22">Risk factors of fractures</searchLink><br /><searchLink fieldCode="DE" term="%22Femur+neck%22">Femur neck</searchLink><br /><searchLink fieldCode="DE" term="%22Ultrasonic+imaging%22">Ultrasonic imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Surgery%22">Surgery</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Abstract: Osteoporosis defines a causal relationship between reduced bone density, reduced mechanical competence of the bone tissue of the sufferers and concomitantly an increased risk of fracture in life. The aims of the present study is: (1) to provide further evidence to support the use of Quantitative Ultrasound (QUS) results from peripheral sites to provide a prediction of the density of the proximal femur; and (2) to provide rational evidence for the well-proven ability of QUS to predict directly ‘risk of fracture’. 20 femoral heads were obtained from 15 Caucasian females and 5 Caucasian males undergoing emergency surgery for a fractured neck of femur. QUS investigations of the calcaneus, proximal phalanx, distal radius and mid-shaft tibia were undertaken on the donors with 72h of surgery. 128 fracture toughness samples and 20 compression cores were manufactured and tested. Significant relationships were found between QUS parameters determined in vivo and the apparent density (g/cm3) of the tissue at the proximal femur and both the fracture toughness and strength determined in vitro from the same donor individual. In this study we relate QUS results obtained in vivo to the actual apparent density of bone tissue from the proximal femur, donated by the same individual, and the fracture toughness and compressive strength. The study demonstrates the ability of QUS investigations at peripheral sites to accurately predict the density of bone from the proximal femur and provides evidence to support the use of QUS to predict the ‘risk of fracture’ directly. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Medical Engineering & Physics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.medengphy.2010.06.014 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 991 Subjects: – SubjectFull: Osteoporosis Type: general – SubjectFull: Femur head Type: general – SubjectFull: Bone mechanics Type: general – SubjectFull: Bone density Type: general – SubjectFull: Risk factors of fractures Type: general – SubjectFull: Femur neck Type: general – SubjectFull: Ultrasonic imaging Type: general – SubjectFull: Surgery Type: general Titles: – TitleFull: Fracture toughness and compressive properties of cancellous bone at the head of the femur and relationships to non-invasive skeletal assessment measurements Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cook, R.B. – PersonEntity: Name: NameFull: Curwen, C. – PersonEntity: Name: NameFull: Tasker, T. – PersonEntity: Name: NameFull: Zioupos, P. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: Nov2010 Type: published Y: 2010 Identifiers: – Type: issn-print Value: 13504533 Numbering: – Type: volume Value: 32 – Type: issue Value: 9 Titles: – TitleFull: Medical Engineering & Physics Type: main |
| ResultId | 1 |
