GROWTH RATE MEASUREMENTS AND DEPOSITION MODELLING OF HYGROSCOPIC AEROSOLS IN HUMAN TRACHEOBRONCHIAL MODELS.
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| Title: | GROWTH RATE MEASUREMENTS AND DEPOSITION MODELLING OF HYGROSCOPIC AEROSOLS IN HUMAN TRACHEOBRONCHIAL MODELS. |
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| Authors: | MARTONEN, TEDDY B.1, BELL, KARL A.1, PHALEN, ROBERT F.1, WILSON, ARCHIE F.1, HO, ABRAHAM1 |
| Source: | Annals of Occupational Hygiene. 05/01/1982, Vol. 26 Issue 1, p93-108. 16p. |
| Abstract: | A laboratory system has been developed in which the atmosphere and fluid dynamics of the upper tracheobronchial (TB) tree of the human are simulated. It is used to measure the hygroscopic growth rates of monodisperse NaCl and bronchodilator (Isuprel hydrochloride with and without glycerine) aerosols. Dry particles are mixed with water vapour-laden air at the entrance to a growth chamber temperature controlled at 37°C with a relative humidity (RH) between 88 and 95%. Hygroscopic growth rates increased with degree of RH and magnitude of Reynolds number in the chamber. The growth data are incorporated into an aerosol deposition model to calculate the effect of hygroscopic growth upon the dose distribution of medicinal aerosols in the human TB network. The model uses some original deposition formulae to compute particle deposition efficiencies. Calculations show that the rate of water vapour absorption within TB airways is an important factor affecting the fate of particles used in aerosol therapy. [ABSTRACT FROM PUBLISHER] |
| Copyright of Annals of Occupational Hygiene is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 56113003 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: GROWTH RATE MEASUREMENTS AND DEPOSITION MODELLING OF HYGROSCOPIC AEROSOLS IN HUMAN TRACHEOBRONCHIAL MODELS. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22MARTONEN%2C+TEDDY+B%2E%22">MARTONEN, TEDDY B.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22BELL%2C+KARL+A%2E%22">BELL, KARL A.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22PHALEN%2C+ROBERT+F%2E%22">PHALEN, ROBERT F.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22WILSON%2C+ARCHIE+F%2E%22">WILSON, ARCHIE F.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22HO%2C+ABRAHAM%22">HO, ABRAHAM</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Annals+of+Occupational+Hygiene%22">Annals of Occupational Hygiene</searchLink>. 05/01/1982, Vol. 26 Issue 1, p93-108. 16p. – Name: Abstract Label: Abstract Group: Ab Data: A laboratory system has been developed in which the atmosphere and fluid dynamics of the upper tracheobronchial (TB) tree of the human are simulated. It is used to measure the hygroscopic growth rates of monodisperse NaCl and bronchodilator (Isuprel hydrochloride with and without glycerine) aerosols. Dry particles are mixed with water vapour-laden air at the entrance to a growth chamber temperature controlled at 37°C with a relative humidity (RH) between 88 and 95%. Hygroscopic growth rates increased with degree of RH and magnitude of Reynolds number in the chamber. The growth data are incorporated into an aerosol deposition model to calculate the effect of hygroscopic growth upon the dose distribution of medicinal aerosols in the human TB network. The model uses some original deposition formulae to compute particle deposition efficiencies. Calculations show that the rate of water vapour absorption within TB airways is an important factor affecting the fate of particles used in aerosol therapy. [ABSTRACT FROM PUBLISHER] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Annals of Occupational Hygiene is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 16 StartPage: 93 Titles: – TitleFull: GROWTH RATE MEASUREMENTS AND DEPOSITION MODELLING OF HYGROSCOPIC AEROSOLS IN HUMAN TRACHEOBRONCHIAL MODELS. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: MARTONEN, TEDDY B. – PersonEntity: Name: NameFull: BELL, KARL A. – PersonEntity: Name: NameFull: PHALEN, ROBERT F. – PersonEntity: Name: NameFull: WILSON, ARCHIE F. – PersonEntity: Name: NameFull: HO, ABRAHAM IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 05/01/1982 Type: published Y: 1982 Identifiers: – Type: issn-print Value: 00034878 Numbering: – Type: volume Value: 26 – Type: issue Value: 1 Titles: – TitleFull: Annals of Occupational Hygiene Type: main |
| ResultId | 1 |
