The Use of Natural Polymers in Tissue Engineering: A Focus on Electrospun Extracellular Matrix Analogues.
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| Title: | The Use of Natural Polymers in Tissue Engineering: A Focus on Electrospun Extracellular Matrix Analogues. |
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| Authors: | Sell, Scott A.1,2 s2sasell@vcu.edu, Wolfe, Patricia S.1 wolfeps@vcu.edu, Garg, Koyal1 gargk@vcu.edu, McCool, Jennifer M.1 mccooljm2@vcu.edu, Rodriguez, Isaac A.1 rodriguezia@vcu.edu, Bowlin, Gary L.1 glbowlin@vcu.edu |
| Source: | Polymers (20734360). Dec2010, Vol. 2 Issue 4, p522-553. 32p. 3 Color Photographs, 2 Diagrams, 1 Chart, 2 Graphs. |
| Subjects: | Biopolymers, Microbial polymers, Tissue engineering, Tissue culture, Biomedical engineering, Electrospinning, Extracellular matrix, Fibrinogen |
| Abstract: | Natural polymers such as collagens, elastin, and fibrinogen make up much of the body's native extracellular matrix (ECM). This ECM provides structure and mechanical integrity to tissues, as well as communicating with the cellular components it supports to help facilitate and regulate daily cellular processes and wound healing. An ideal tissue engineering scaffold would not only replicate the structure of this ECM, but would also replicate the many functions that the ECM performs. In the past decade, the process of electrospinning has proven effective in creating non-woven ECM analogue scaffolds of micro to nanoscale diameter fibers from an array of synthetic and natural polymers. The ability of this fabrication technique to utilize the aforementioned natural polymers to create tissue engineering scaffolds has yielded promising results, both in vitro and in vivo, due in part to the enhanced bioactivity afforded by materials normally found within the human body. This review will present the process of electrospinning and describe the use of natural polymers in the creation of bioactive ECM analogues in tissue engineering. [ABSTRACT FROM AUTHOR] |
| Copyright of Polymers (20734360) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 57994992 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The Use of Natural Polymers in Tissue Engineering: A Focus on Electrospun Extracellular Matrix Analogues. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sell%2C+Scott+A%2E%22">Sell, Scott A.</searchLink><relatesTo>1,2</relatesTo><i> s2sasell@vcu.edu</i><br /><searchLink fieldCode="AR" term="%22Wolfe%2C+Patricia+S%2E%22">Wolfe, Patricia S.</searchLink><relatesTo>1</relatesTo><i> wolfeps@vcu.edu</i><br /><searchLink fieldCode="AR" term="%22Garg%2C+Koyal%22">Garg, Koyal</searchLink><relatesTo>1</relatesTo><i> gargk@vcu.edu</i><br /><searchLink fieldCode="AR" term="%22McCool%2C+Jennifer+M%2E%22">McCool, Jennifer M.</searchLink><relatesTo>1</relatesTo><i> mccooljm2@vcu.edu</i><br /><searchLink fieldCode="AR" term="%22Rodriguez%2C+Isaac+A%2E%22">Rodriguez, Isaac A.</searchLink><relatesTo>1</relatesTo><i> rodriguezia@vcu.edu</i><br /><searchLink fieldCode="AR" term="%22Bowlin%2C+Gary+L%2E%22">Bowlin, Gary L.</searchLink><relatesTo>1</relatesTo><i> glbowlin@vcu.edu</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Polymers+%2820734360%29%22">Polymers (20734360)</searchLink>. Dec2010, Vol. 2 Issue 4, p522-553. 32p. 3 Color Photographs, 2 Diagrams, 1 Chart, 2 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Biopolymers%22">Biopolymers</searchLink><br /><searchLink fieldCode="DE" term="%22Microbial+polymers%22">Microbial polymers</searchLink><br /><searchLink fieldCode="DE" term="%22Tissue+engineering%22">Tissue engineering</searchLink><br /><searchLink fieldCode="DE" term="%22Tissue+culture%22">Tissue culture</searchLink><br /><searchLink fieldCode="DE" term="%22Biomedical+engineering%22">Biomedical engineering</searchLink><br /><searchLink fieldCode="DE" term="%22Electrospinning%22">Electrospinning</searchLink><br /><searchLink fieldCode="DE" term="%22Extracellular+matrix%22">Extracellular matrix</searchLink><br /><searchLink fieldCode="DE" term="%22Fibrinogen%22">Fibrinogen</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Natural polymers such as collagens, elastin, and fibrinogen make up much of the body's native extracellular matrix (ECM). This ECM provides structure and mechanical integrity to tissues, as well as communicating with the cellular components it supports to help facilitate and regulate daily cellular processes and wound healing. An ideal tissue engineering scaffold would not only replicate the structure of this ECM, but would also replicate the many functions that the ECM performs. In the past decade, the process of electrospinning has proven effective in creating non-woven ECM analogue scaffolds of micro to nanoscale diameter fibers from an array of synthetic and natural polymers. The ability of this fabrication technique to utilize the aforementioned natural polymers to create tissue engineering scaffolds has yielded promising results, both in vitro and in vivo, due in part to the enhanced bioactivity afforded by materials normally found within the human body. This review will present the process of electrospinning and describe the use of natural polymers in the creation of bioactive ECM analogues in tissue engineering. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Polymers (20734360) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/polym2040522 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 32 StartPage: 522 Subjects: – SubjectFull: Biopolymers Type: general – SubjectFull: Microbial polymers Type: general – SubjectFull: Tissue engineering Type: general – SubjectFull: Tissue culture Type: general – SubjectFull: Biomedical engineering Type: general – SubjectFull: Electrospinning Type: general – SubjectFull: Extracellular matrix Type: general – SubjectFull: Fibrinogen Type: general Titles: – TitleFull: The Use of Natural Polymers in Tissue Engineering: A Focus on Electrospun Extracellular Matrix Analogues. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sell, Scott A. – PersonEntity: Name: NameFull: Wolfe, Patricia S. – PersonEntity: Name: NameFull: Garg, Koyal – PersonEntity: Name: NameFull: McCool, Jennifer M. – PersonEntity: Name: NameFull: Rodriguez, Isaac A. – PersonEntity: Name: NameFull: Bowlin, Gary L. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2010 Type: published Y: 2010 Identifiers: – Type: issn-print Value: 20734360 Numbering: – Type: volume Value: 2 – Type: issue Value: 4 Titles: – TitleFull: Polymers (20734360) Type: main |
| ResultId | 1 |
