Precision rodent whisker stimulator with integrated servo-locked control and displacement measurement
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| Title: | Precision rodent whisker stimulator with integrated servo-locked control and displacement measurement |
|---|---|
| Authors: | Walker, Jennifer L.1, Monjaraz-Fuentes, Fernanda1, Pedrow, Christi R.1, Rector, David M. drector@vetmed.wsu.edu |
| Source: | Journal of Neuroscience Methods. Mar2011, Vol. 196 Issue 1, p20-30. 11p. |
| Subjects: | Laboratory rodents, Whiskers, Neural stimulation, Anesthesia in neurology, Auditory perception, Evoked response audiometry, Electrophysiology |
| Abstract: | Abstract: We developed a high speed voice coil based whisker stimulator that delivers precise deflections of a single whisker or group of whiskers in a repeatable manner. The device is miniature, quiet, and inexpensive to build. Multiple stimulators fit together for independent stimulation of four or more whiskers. The system can be used with animals under anesthesia as well as awake animals with head-restraint, and does not require trimming the whiskers. The system can deliver 1–2mm deflections in 2ms resulting in velocities up to 900mm/s to attain a wide range of evoked responses. Since auditory artifacts can influence behavioral studies using whisker stimulation, we tested potential effects of auditory noise by recording somatosensory evoked potentials (SEP) with varying auditory click levels, and with/without 80dBa background white noise. We found that auditory clicks as low as 40dBa significantly influence the SEP. With background white noise, auditory clicks as low as 50dBa were still detected in components of the SEP. For behavioral studies where animals must learn to respond to whisker stimulation, these sounds must be minimized. Together, the stimulator and data system can be used for psychometric vigilance tasks, mapping of the barrel cortex and other electrophysiological paradigms. [Copyright &y& Elsevier] |
| Copyright of Journal of Neuroscience Methods is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 58095284 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Precision rodent whisker stimulator with integrated servo-locked control and displacement measurement – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Walker%2C+Jennifer+L%2E%22">Walker, Jennifer L.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Monjaraz-Fuentes%2C+Fernanda%22">Monjaraz-Fuentes, Fernanda</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Pedrow%2C+Christi+R%2E%22">Pedrow, Christi R.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rector%2C+David+M%2E%22">Rector, David M.</searchLink><i> drector@vetmed.wsu.edu</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Neuroscience+Methods%22">Journal of Neuroscience Methods</searchLink>. Mar2011, Vol. 196 Issue 1, p20-30. 11p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Laboratory+rodents%22">Laboratory rodents</searchLink><br /><searchLink fieldCode="DE" term="%22Whiskers%22">Whiskers</searchLink><br /><searchLink fieldCode="DE" term="%22Neural+stimulation%22">Neural stimulation</searchLink><br /><searchLink fieldCode="DE" term="%22Anesthesia+in+neurology%22">Anesthesia in neurology</searchLink><br /><searchLink fieldCode="DE" term="%22Auditory+perception%22">Auditory perception</searchLink><br /><searchLink fieldCode="DE" term="%22Evoked+response+audiometry%22">Evoked response audiometry</searchLink><br /><searchLink fieldCode="DE" term="%22Electrophysiology%22">Electrophysiology</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Abstract: We developed a high speed voice coil based whisker stimulator that delivers precise deflections of a single whisker or group of whiskers in a repeatable manner. The device is miniature, quiet, and inexpensive to build. Multiple stimulators fit together for independent stimulation of four or more whiskers. The system can be used with animals under anesthesia as well as awake animals with head-restraint, and does not require trimming the whiskers. The system can deliver 1–2mm deflections in 2ms resulting in velocities up to 900mm/s to attain a wide range of evoked responses. Since auditory artifacts can influence behavioral studies using whisker stimulation, we tested potential effects of auditory noise by recording somatosensory evoked potentials (SEP) with varying auditory click levels, and with/without 80dBa background white noise. We found that auditory clicks as low as 40dBa significantly influence the SEP. With background white noise, auditory clicks as low as 50dBa were still detected in components of the SEP. For behavioral studies where animals must learn to respond to whisker stimulation, these sounds must be minimized. Together, the stimulator and data system can be used for psychometric vigilance tasks, mapping of the barrel cortex and other electrophysiological paradigms. [Copyright &y& Elsevier] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Neuroscience Methods is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jneumeth.2010.12.008 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 11 StartPage: 20 Subjects: – SubjectFull: Laboratory rodents Type: general – SubjectFull: Whiskers Type: general – SubjectFull: Neural stimulation Type: general – SubjectFull: Anesthesia in neurology Type: general – SubjectFull: Auditory perception Type: general – SubjectFull: Evoked response audiometry Type: general – SubjectFull: Electrophysiology Type: general Titles: – TitleFull: Precision rodent whisker stimulator with integrated servo-locked control and displacement measurement Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Walker, Jennifer L. – PersonEntity: Name: NameFull: Monjaraz-Fuentes, Fernanda – PersonEntity: Name: NameFull: Pedrow, Christi R. – PersonEntity: Name: NameFull: Rector, David M. IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 03 Text: Mar2011 Type: published Y: 2011 Identifiers: – Type: issn-print Value: 01650270 Numbering: – Type: volume Value: 196 – Type: issue Value: 1 Titles: – TitleFull: Journal of Neuroscience Methods Type: main |
| ResultId | 1 |
