Effect of the fixator stiffness on the young regenerate bone after bone transport: Computational approach
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| Title: | Effect of the fixator stiffness on the young regenerate bone after bone transport: Computational approach |
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| Authors: | Reina-Romo, E.1 erreina@us.es, Gómez-Benito, M.J.2 gomezmj@unizar.es, Domínguez, J.1, Niemeyer, F.3, Wehner, T.3, Simon, U.3, Claes, L.E.3 |
| Source: | Journal of Biomechanics. Mar2011, Vol. 44 Issue 5, p917-923. 7p. |
| Subjects: | Bone regeneration, Stiffness (Mechanics), Bone abnormalities, Tissue fixation (Histology), Biomechanics, Osteogenesis imperfecta, Patients |
| Abstract: | Abstract: Bone transport is a well accepted technique for the treatment of large bony defects. This process is mechanically driven, where mechanical forces play a central role in the development of tissues within the distracted gap. One of the most important mechanical factors that conditions the success of bone regeneration during distraction osteogenesis is the fixator stiffness not only during the distraction phase but also during the consolidation phase. Therefore, the aim of the present work is to evaluate the effect of the stiffness of the fixator device on the interfragmentary movements and the tissue outcome during the consolidation phase. A previous differentiation model () is extended in order to take into account the different behaviors of the tissues in tension and compression. The numerical results that were computed concur with experimental findings; a stiff fixator promotes bone formation while the excessive motion induced by extremely flexible fixators is adverse for bony bridging. Experimental interfragmentary movement is similar to that computed numerically. [Copyright &y& Elsevier] |
| Copyright of Journal of Biomechanics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 58749058 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Effect of the fixator stiffness on the young regenerate bone after bone transport: Computational approach – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Reina-Romo%2C+E%2E%22">Reina-Romo, E.</searchLink><relatesTo>1</relatesTo><i> erreina@us.es</i><br /><searchLink fieldCode="AR" term="%22Gómez-Benito%2C+M%2EJ%2E%22">Gómez-Benito, M.J.</searchLink><relatesTo>2</relatesTo><i> gomezmj@unizar.es</i><br /><searchLink fieldCode="AR" term="%22Domínguez%2C+J%2E%22">Domínguez, J.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Niemeyer%2C+F%2E%22">Niemeyer, F.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Wehner%2C+T%2E%22">Wehner, T.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Simon%2C+U%2E%22">Simon, U.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Claes%2C+L%2EE%2E%22">Claes, L.E.</searchLink><relatesTo>3</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Biomechanics%22">Journal of Biomechanics</searchLink>. Mar2011, Vol. 44 Issue 5, p917-923. 7p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Bone+regeneration%22">Bone regeneration</searchLink><br /><searchLink fieldCode="DE" term="%22Stiffness+%28Mechanics%29%22">Stiffness (Mechanics)</searchLink><br /><searchLink fieldCode="DE" term="%22Bone+abnormalities%22">Bone abnormalities</searchLink><br /><searchLink fieldCode="DE" term="%22Tissue+fixation+%28Histology%29%22">Tissue fixation (Histology)</searchLink><br /><searchLink fieldCode="DE" term="%22Biomechanics%22">Biomechanics</searchLink><br /><searchLink fieldCode="DE" term="%22Osteogenesis+imperfecta%22">Osteogenesis imperfecta</searchLink><br /><searchLink fieldCode="DE" term="%22Patients%22">Patients</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Abstract: Bone transport is a well accepted technique for the treatment of large bony defects. This process is mechanically driven, where mechanical forces play a central role in the development of tissues within the distracted gap. One of the most important mechanical factors that conditions the success of bone regeneration during distraction osteogenesis is the fixator stiffness not only during the distraction phase but also during the consolidation phase. Therefore, the aim of the present work is to evaluate the effect of the stiffness of the fixator device on the interfragmentary movements and the tissue outcome during the consolidation phase. A previous differentiation model () is extended in order to take into account the different behaviors of the tissues in tension and compression. The numerical results that were computed concur with experimental findings; a stiff fixator promotes bone formation while the excessive motion induced by extremely flexible fixators is adverse for bony bridging. Experimental interfragmentary movement is similar to that computed numerically. [Copyright &y& Elsevier] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Biomechanics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jbiomech.2010.11.033 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 917 Subjects: – SubjectFull: Bone regeneration Type: general – SubjectFull: Stiffness (Mechanics) Type: general – SubjectFull: Bone abnormalities Type: general – SubjectFull: Tissue fixation (Histology) Type: general – SubjectFull: Biomechanics Type: general – SubjectFull: Osteogenesis imperfecta Type: general – SubjectFull: Patients Type: general Titles: – TitleFull: Effect of the fixator stiffness on the young regenerate bone after bone transport: Computational approach Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Reina-Romo, E. – PersonEntity: Name: NameFull: Gómez-Benito, M.J. – PersonEntity: Name: NameFull: Domínguez, J. – PersonEntity: Name: NameFull: Niemeyer, F. – PersonEntity: Name: NameFull: Wehner, T. – PersonEntity: Name: NameFull: Simon, U. – PersonEntity: Name: NameFull: Claes, L.E. IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 03 Text: Mar2011 Type: published Y: 2011 Identifiers: – Type: issn-print Value: 00219290 Numbering: – Type: volume Value: 44 – Type: issue Value: 5 Titles: – TitleFull: Journal of Biomechanics Type: main |
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