Origins of the ultrashort- T.
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| Title: | Origins of the ultrashort- T. |
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| Authors: | Horch, R. Adam1,2, Gore, John C.1,2,3,4, Does, Mark D.1,2,3,5 |
| Source: | Magnetic Resonance in Medicine. Jul2011, Vol. 66 Issue 1, p24-31. 8p. |
| Abstract: | Recently developed MRI techniques have enabled clinical imaging of short-lived H NMR signals with T < 1 ms. Using these techniques, novel signal enhancement has been observed in myelinated tissues, although the source of this enhancement has not been identified. Herein, we report studies of the nature and origins of ultrashort T (u T) signals (50 μs < T < 1 ms) from amphibian and mammalian myelinated nerves. NMR measurements and comparisons with myelin phantoms and expected myelin components indicate that these u T signals arise predominantly from methylene H on/in the myelin membranes, which suggests that direct measurement of u T signals can be used as a new means for quantitative myelin mapping. Magn Reson Med, 2011. © 2011 Wiley-Liss, Inc. [ABSTRACT FROM AUTHOR] |
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| Database: | Engineering Source |
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