View in EDS

Spatial variation of blood viscosity: Modelling using shear fields measured by a μPIV based technique

Saved in:
Bibliographic Details
Title: Spatial variation of blood viscosity: Modelling using shear fields measured by a μPIV based technique
Authors: Kaliviotis, Efstathios efstathios.kaliviotis@kcl.ac.uk, Dusting, Jonathan1, Balabani, Stavroula1
Source: Medical Engineering & Physics. Sep2011, Vol. 33 Issue 7, p824-831. 8p.
Subjects: Blood viscosity, Spatial variation, Shear (Mechanics), Blood flow, Erythrocytes, Estimation theory, Microstructure
Abstract: Abstract: The spatial characteristics of blood viscosity were investigated by combining a newly developed constitutive equation with shear deformation fields calculated from velocity measurements obtained by a μPIV based technique. Blood at physiological hematocrit levels and in the presence of aggregation was sheared in a narrow gap plate–plate geometry and the velocity and aggregation characteristics were determined from images captured using a high resolution camera. Changes in the microstructure of blood caused by aggregation were observed to affect the flow characteristics. At low shear rates, high aggregation and network formation caused the RBC motion to become essentially two-dimensional. The measured velocity fields were used to estimate the magnitude of shear which was subsequently used in conjunction with the new model to assess the spatial variation of viscosity across the flow domain. It was found that the non-uniform microstructural characteristics of blood influence its viscosity distribution accordingly. The viscosity of blood estimated in the core of the examined flow, using a zero-gradient core velocity profile assumption, was found to be significantly higher than the overall effective viscosity determined using other velocity profile assumptions. [Copyright &y& Elsevier]
Copyright of Medical Engineering & Physics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 63985306
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Spatial variation of blood viscosity: Modelling using shear fields measured by a μPIV based technique
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Kaliviotis%2C+Efstathios%22">Kaliviotis, Efstathios</searchLink><i> efstathios.kaliviotis@kcl.ac.uk</i><br /><searchLink fieldCode="AR" term="%22Dusting%2C+Jonathan%22">Dusting, Jonathan</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Balabani%2C+Stavroula%22">Balabani, Stavroula</searchLink><relatesTo>1</relatesTo>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Medical+Engineering+%26+Physics%22">Medical Engineering & Physics</searchLink>. Sep2011, Vol. 33 Issue 7, p824-831. 8p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Blood+viscosity%22">Blood viscosity</searchLink><br /><searchLink fieldCode="DE" term="%22Spatial+variation%22">Spatial variation</searchLink><br /><searchLink fieldCode="DE" term="%22Shear+%28Mechanics%29%22">Shear (Mechanics)</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+flow%22">Blood flow</searchLink><br /><searchLink fieldCode="DE" term="%22Erythrocytes%22">Erythrocytes</searchLink><br /><searchLink fieldCode="DE" term="%22Estimation+theory%22">Estimation theory</searchLink><br /><searchLink fieldCode="DE" term="%22Microstructure%22">Microstructure</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Abstract: The spatial characteristics of blood viscosity were investigated by combining a newly developed constitutive equation with shear deformation fields calculated from velocity measurements obtained by a μPIV based technique. Blood at physiological hematocrit levels and in the presence of aggregation was sheared in a narrow gap plate–plate geometry and the velocity and aggregation characteristics were determined from images captured using a high resolution camera. Changes in the microstructure of blood caused by aggregation were observed to affect the flow characteristics. At low shear rates, high aggregation and network formation caused the RBC motion to become essentially two-dimensional. The measured velocity fields were used to estimate the magnitude of shear which was subsequently used in conjunction with the new model to assess the spatial variation of viscosity across the flow domain. It was found that the non-uniform microstructural characteristics of blood influence its viscosity distribution accordingly. The viscosity of blood estimated in the core of the examined flow, using a zero-gradient core velocity profile assumption, was found to be significantly higher than the overall effective viscosity determined using other velocity profile assumptions. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Medical Engineering & Physics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=63985306
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.medengphy.2010.09.004
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 824
    Subjects:
      – SubjectFull: Blood viscosity
        Type: general
      – SubjectFull: Spatial variation
        Type: general
      – SubjectFull: Shear (Mechanics)
        Type: general
      – SubjectFull: Blood flow
        Type: general
      – SubjectFull: Erythrocytes
        Type: general
      – SubjectFull: Estimation theory
        Type: general
      – SubjectFull: Microstructure
        Type: general
    Titles:
      – TitleFull: Spatial variation of blood viscosity: Modelling using shear fields measured by a μPIV based technique
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Kaliviotis, Efstathios
      – PersonEntity:
          Name:
            NameFull: Dusting, Jonathan
      – PersonEntity:
          Name:
            NameFull: Balabani, Stavroula
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: Sep2011
              Type: published
              Y: 2011
          Identifiers:
            – Type: issn-print
              Value: 13504533
          Numbering:
            – Type: volume
              Value: 33
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Medical Engineering & Physics
              Type: main
ResultId 1