Static and rotational step-and-shoot IMRT treatment plans for the prostate: A risk comparison study.
Saved in:
| Title: | Static and rotational step-and-shoot IMRT treatment plans for the prostate: A risk comparison study. |
|---|---|
| Authors: | Blais, Adam Richard1, Lederer, Ernst2, Oliver, Michael2, Leszczynski, Konrad3 |
| Source: | Medical Physics. Feb2012, Vol. 39 Issue 2, p1069-1078. 10p. |
| Subjects: | Comparative studies, Radiotherapy, Prostate, Drug dosage, Medical statistics, Electrotherapeutics, Reporting of diseases |
| Abstract: | Purpose: For certain clinical applications, rotational intensity modulated radiation therapy (R-IMRT) techniques such as volumetric modulated arc therapy (VMAT) are capable of improved target dose coverage and shorter delivery time when compared to static, step-and-shoot IMRT. The authors performed a risk comparison study for two standard step-and-shoot IMRT plans and two step-and-shoot Rotational IMRT plans that were designed specifically for a Siemens Primus linear accelerator. Methods: CT images of a RANDO phantom were used to generate R-IMRT and static IMRT plans. One simple and one complex prostate cases were created to investigate these techniques. The R-IMRT plans consisted of 72 single-segmented 6 MV beams, equally spaced with beam angle separations of 5°. The static IMRT plans employed seven multisegmented 6 MV beams. Both types of plans were optimized in Pinnacle3 with the direct machine parameter optimization (DMPO) algorithm using the same set of optimization objectives. The plans were delivered to a RANDO phantom and thermoluminescent diode (TLD) dose measurements were performed at various locations throughout the phantom. Risk coefficients and organ weightings as defined by International Commission on Radiological Protection (ICRP) Publication 103 were used to calculate the resulting effective doses to various organs at risk, as well as the overall risk estimate for both techniques. Results: For the simple prostate case, the R-IMRT technique provided a higher dose to organs at risk within the CT volume and a lower overall peripheral dose to remaining organs. The R-IMRT plan had a risk estimate of 4.56% when compared to the IMRT risk of 4.78%. For the complex prostate case, there was no significant difference in the lifetime risks of the IMRT (5.73%) and R-IMRT (5.74%) plans. Conclusions: R-IMRT is an approximation to VMAT and it was found that there is no clinically significant difference between lifetime risk estimates between R-IMRT and standard seven-beam IMRT for the prostate. [ABSTRACT FROM AUTHOR] |
| Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: egs DbLabel: Engineering Source An: 71531676 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Static and rotational step-and-shoot IMRT treatment plans for the prostate: A risk comparison study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Blais%2C+Adam+Richard%22">Blais, Adam Richard</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Lederer%2C+Ernst%22">Lederer, Ernst</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Oliver%2C+Michael%22">Oliver, Michael</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Leszczynski%2C+Konrad%22">Leszczynski, Konrad</searchLink><relatesTo>3</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Medical+Physics%22">Medical Physics</searchLink>. Feb2012, Vol. 39 Issue 2, p1069-1078. 10p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Radiotherapy%22">Radiotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Prostate%22">Prostate</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+dosage%22">Drug dosage</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+statistics%22">Medical statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Electrotherapeutics%22">Electrotherapeutics</searchLink><br /><searchLink fieldCode="DE" term="%22Reporting+of+diseases%22">Reporting of diseases</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: For certain clinical applications, rotational intensity modulated radiation therapy (R-IMRT) techniques such as volumetric modulated arc therapy (VMAT) are capable of improved target dose coverage and shorter delivery time when compared to static, step-and-shoot IMRT. The authors performed a risk comparison study for two standard step-and-shoot IMRT plans and two step-and-shoot Rotational IMRT plans that were designed specifically for a Siemens Primus linear accelerator. Methods: CT images of a RANDO phantom were used to generate R-IMRT and static IMRT plans. One simple and one complex prostate cases were created to investigate these techniques. The R-IMRT plans consisted of 72 single-segmented 6 MV beams, equally spaced with beam angle separations of 5°. The static IMRT plans employed seven multisegmented 6 MV beams. Both types of plans were optimized in Pinnacle3 with the direct machine parameter optimization (DMPO) algorithm using the same set of optimization objectives. The plans were delivered to a RANDO phantom and thermoluminescent diode (TLD) dose measurements were performed at various locations throughout the phantom. Risk coefficients and organ weightings as defined by International Commission on Radiological Protection (ICRP) Publication 103 were used to calculate the resulting effective doses to various organs at risk, as well as the overall risk estimate for both techniques. Results: For the simple prostate case, the R-IMRT technique provided a higher dose to organs at risk within the CT volume and a lower overall peripheral dose to remaining organs. The R-IMRT plan had a risk estimate of 4.56% when compared to the IMRT risk of 4.78%. For the complex prostate case, there was no significant difference in the lifetime risks of the IMRT (5.73%) and R-IMRT (5.74%) plans. Conclusions: R-IMRT is an approximation to VMAT and it was found that there is no clinically significant difference between lifetime risk estimates between R-IMRT and standard seven-beam IMRT for the prostate. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=71531676 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1118/1.3679338 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 1069 Subjects: – SubjectFull: Comparative studies Type: general – SubjectFull: Radiotherapy Type: general – SubjectFull: Prostate Type: general – SubjectFull: Drug dosage Type: general – SubjectFull: Medical statistics Type: general – SubjectFull: Electrotherapeutics Type: general – SubjectFull: Reporting of diseases Type: general Titles: – TitleFull: Static and rotational step-and-shoot IMRT treatment plans for the prostate: A risk comparison study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Blais, Adam Richard – PersonEntity: Name: NameFull: Lederer, Ernst – PersonEntity: Name: NameFull: Oliver, Michael – PersonEntity: Name: NameFull: Leszczynski, Konrad IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb2012 Type: published Y: 2012 Identifiers: – Type: issn-print Value: 00942405 Numbering: – Type: volume Value: 39 – Type: issue Value: 2 Titles: – TitleFull: Medical Physics Type: main |
| ResultId | 1 |
