Delivery Modulation inSilica Mesoporous Supportsvia Alkyl Chain Pore Outlet Decoration.
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| Title: | Delivery Modulation inSilica Mesoporous Supportsvia Alkyl Chain Pore Outlet Decoration. |
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| Authors: | Aznar, Elena1, Sancenón, Félix1, Marcos, M. Dolores1, Martínez-Máñez, Ramón1, Stroeve, Pieter1, Cano, Joan1, Amorós, Pedro1 |
| Source: | Langmuir. Feb2012, Vol. 28 Issue 5, p2986-2996. 11p. |
| Subjects: | Mesoporous materials, Silica, Transition metal complexes, Controlled release technology, Dyes & dyeing, Organoruthenium compounds, Molecular dynamics, Simulation methods & models |
| Abstract: | This article focuses on the study of the release ratein a familyof modified silica mesoporous supports. A collection of solids containingethyl, butyl, hexyl, octyl, decyl, octadecyl, docosyl, and triacontylgroups anchored on the pore outlets of mesoporous MCM-41 has beenprepared and characterized. Controlled release from pore voids hasbeen studied through the delivery of the dye complex tris(2,2′-bipyridyl)ruthenium(II).Delivery rates were found to be dependent on the alkyl chain lengthanchored on the pore outlets of the mesoporous scaffolding. Moreover,release rates follow a Higuchi diffusion model, and Higuchi constantsfor the different hybrid solids have been calculated. A decrease ofthe Higuchi constants was observed as the alkyl chain used to tunethe release profile is longer, confirming the effect that the differentalkyl chains anchored into the pore mouths exerted on the deliveryof the cargo. Furthermore, to better understand the relation betweenpore outlets decoration and release rate, studies using moleculardynamics simulations employing force-field methods have been carriedout. A good agreement between the calculations and the experimentalobservations was observed. [ABSTRACT FROM AUTHOR] |
| Copyright of Langmuir is the property of American Chemical Society and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 71602476 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Delivery Modulation inSilica Mesoporous Supportsvia Alkyl Chain Pore Outlet Decoration. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Aznar%2C+Elena%22">Aznar, Elena</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Sancenón%2C+Félix%22">Sancenón, Félix</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Marcos%2C+M%2E+Dolores%22">Marcos, M. Dolores</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Martínez-Máñez%2C+Ramón%22">Martínez-Máñez, Ramón</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Stroeve%2C+Pieter%22">Stroeve, Pieter</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Cano%2C+Joan%22">Cano, Joan</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Amorós%2C+Pedro%22">Amorós, Pedro</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Langmuir%22">Langmuir</searchLink>. Feb2012, Vol. 28 Issue 5, p2986-2996. 11p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Mesoporous+materials%22">Mesoporous materials</searchLink><br /><searchLink fieldCode="DE" term="%22Silica%22">Silica</searchLink><br /><searchLink fieldCode="DE" term="%22Transition+metal+complexes%22">Transition metal complexes</searchLink><br /><searchLink fieldCode="DE" term="%22Controlled+release+technology%22">Controlled release technology</searchLink><br /><searchLink fieldCode="DE" term="%22Dyes+%26+dyeing%22">Dyes & dyeing</searchLink><br /><searchLink fieldCode="DE" term="%22Organoruthenium+compounds%22">Organoruthenium compounds</searchLink><br /><searchLink fieldCode="DE" term="%22Molecular+dynamics%22">Molecular dynamics</searchLink><br /><searchLink fieldCode="DE" term="%22Simulation+methods+%26+models%22">Simulation methods & models</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: This article focuses on the study of the release ratein a familyof modified silica mesoporous supports. A collection of solids containingethyl, butyl, hexyl, octyl, decyl, octadecyl, docosyl, and triacontylgroups anchored on the pore outlets of mesoporous MCM-41 has beenprepared and characterized. Controlled release from pore voids hasbeen studied through the delivery of the dye complex tris(2,2′-bipyridyl)ruthenium(II).Delivery rates were found to be dependent on the alkyl chain lengthanchored on the pore outlets of the mesoporous scaffolding. Moreover,release rates follow a Higuchi diffusion model, and Higuchi constantsfor the different hybrid solids have been calculated. A decrease ofthe Higuchi constants was observed as the alkyl chain used to tunethe release profile is longer, confirming the effect that the differentalkyl chains anchored into the pore mouths exerted on the deliveryof the cargo. Furthermore, to better understand the relation betweenpore outlets decoration and release rate, studies using moleculardynamics simulations employing force-field methods have been carriedout. A good agreement between the calculations and the experimentalobservations was observed. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Langmuir is the property of American Chemical Society and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/la204438j Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 11 StartPage: 2986 Subjects: – SubjectFull: Mesoporous materials Type: general – SubjectFull: Silica Type: general – SubjectFull: Transition metal complexes Type: general – SubjectFull: Controlled release technology Type: general – SubjectFull: Dyes & dyeing Type: general – SubjectFull: Organoruthenium compounds Type: general – SubjectFull: Molecular dynamics Type: general – SubjectFull: Simulation methods & models Type: general Titles: – TitleFull: Delivery Modulation inSilica Mesoporous Supportsvia Alkyl Chain Pore Outlet Decoration. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Aznar, Elena – PersonEntity: Name: NameFull: Sancenón, Félix – PersonEntity: Name: NameFull: Marcos, M. Dolores – PersonEntity: Name: NameFull: Martínez-Máñez, Ramón – PersonEntity: Name: NameFull: Stroeve, Pieter – PersonEntity: Name: NameFull: Cano, Joan – PersonEntity: Name: NameFull: Amorós, Pedro IsPartOfRelationships: – BibEntity: Dates: – D: 07 M: 02 Text: Feb2012 Type: published Y: 2012 Identifiers: – Type: issn-print Value: 07437463 Numbering: – Type: volume Value: 28 – Type: issue Value: 5 Titles: – TitleFull: Langmuir Type: main |
| ResultId | 1 |
