View in EDS

The place escape/avoidance paradigm:: A novel method to assess nociceptive processing.

Saved in:
Bibliographic Details
Title: The place escape/avoidance paradigm:: A novel method to assess nociceptive processing.
Authors: Fuchs, Perry N.1 fuchs@uta.edu, McNabb, Christopher T.1
Source: Journal of Integrative Neuroscience. Mar2012, Vol. 11 Issue 1, p61-72. 12p.
Subjects: Pain in animals, Laboratory rodents, Rodent behavior, Chronic pain, Escape (Psychology), Neurosciences
Abstract: This paper summarizes a behavioral paradigm that was developed as a novel method to dissociate the multidimensional pain experience in rodents. The place escape/avoidance paradigm (PEAP) is based on the assumption that if animals escape and/or avoid a noxious stimulus, then the stimulus is aversive to the animal. Data is presented showing that when animals are placed in a specific environmental condition, they will perform purposeful behavior to escape and/or avoid the noxious stimulus. Additional data is presented to demonstrate the validity of the behavioral paradigm and how the paradigm has been used to test the hypothesis that the affective/motivational dimension of pain can be dissociated and studied independent of sensory pain processing. The behavioral paradigm highlights the emerging trend in the area of pain research and management towards developing more realistic behavioral paradigms to assess nociceptive processing in rodent models of chronic pain. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Integrative Neuroscience is the property of IMR Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 73360911
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The place escape/avoidance paradigm:: A novel method to assess nociceptive processing.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Fuchs%2C+Perry+N%2E%22">Fuchs, Perry N.</searchLink><relatesTo>1</relatesTo><i> fuchs@uta.edu</i><br /><searchLink fieldCode="AR" term="%22McNabb%2C+Christopher+T%2E%22">McNabb, Christopher T.</searchLink><relatesTo>1</relatesTo>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Journal+of+Integrative+Neuroscience%22">Journal of Integrative Neuroscience</searchLink>. Mar2012, Vol. 11 Issue 1, p61-72. 12p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Pain+in+animals%22">Pain in animals</searchLink><br /><searchLink fieldCode="DE" term="%22Laboratory+rodents%22">Laboratory rodents</searchLink><br /><searchLink fieldCode="DE" term="%22Rodent+behavior%22">Rodent behavior</searchLink><br /><searchLink fieldCode="DE" term="%22Chronic+pain%22">Chronic pain</searchLink><br /><searchLink fieldCode="DE" term="%22Escape+%28Psychology%29%22">Escape (Psychology)</searchLink><br /><searchLink fieldCode="DE" term="%22Neurosciences%22">Neurosciences</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: This paper summarizes a behavioral paradigm that was developed as a novel method to dissociate the multidimensional pain experience in rodents. The place escape/avoidance paradigm (PEAP) is based on the assumption that if animals escape and/or avoid a noxious stimulus, then the stimulus is aversive to the animal. Data is presented showing that when animals are placed in a specific environmental condition, they will perform purposeful behavior to escape and/or avoid the noxious stimulus. Additional data is presented to demonstrate the validity of the behavioral paradigm and how the paradigm has been used to test the hypothesis that the affective/motivational dimension of pain can be dissociated and studied independent of sensory pain processing. The behavioral paradigm highlights the emerging trend in the area of pain research and management towards developing more realistic behavioral paradigms to assess nociceptive processing in rodent models of chronic pain. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Integrative Neuroscience is the property of IMR Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=73360911
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1142/S0219635212500045
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 61
    Subjects:
      – SubjectFull: Pain in animals
        Type: general
      – SubjectFull: Laboratory rodents
        Type: general
      – SubjectFull: Rodent behavior
        Type: general
      – SubjectFull: Chronic pain
        Type: general
      – SubjectFull: Escape (Psychology)
        Type: general
      – SubjectFull: Neurosciences
        Type: general
    Titles:
      – TitleFull: The place escape/avoidance paradigm:: A novel method to assess nociceptive processing.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Fuchs, Perry N.
      – PersonEntity:
          Name:
            NameFull: McNabb, Christopher T.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: Mar2012
              Type: published
              Y: 2012
          Identifiers:
            – Type: issn-print
              Value: 02196352
          Numbering:
            – Type: volume
              Value: 11
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Journal of Integrative Neuroscience
              Type: main
ResultId 1