View in EDS PDF Full Text

A novel curvilinear approach for prostate seed implantation.

Saved in:
Bibliographic Details
Title: A novel curvilinear approach for prostate seed implantation.
Authors: Podder, Tarun K.1, Dicker, Adam P.2, Hutapea, Parsaoran3, Darvish, Kurosh3, Yu, Yan2
Source: Medical Physics. Apr2012, Vol. 39 Issue 4, p1887-1892. 6p.
Subjects: Dosimeters, Radioisotope brachytherapy, Radiation doses, Prostate cancer, Rectal radiography, Parameter estimation, Health outcome assessment
Abstract: Purpose: A new technique called 'curvilinear approach' for prostate seed implantation has been proposed. The purpose of this study is to evaluate the dosimetric benefit of curvilinear distribution of seeds for low-dose-rate (LDR) prostate brachytherapy. Methods: Twenty LDR prostate brachytherapy cases planned intraoperatively with VariSeed planning system and I-125 seeds were randomly selected as reference rectilinear cases. All the cases were replanned by using curved-needle approach keeping the same individual source strength and the volume receiving 100% of prescribed dose 145 Gy (V100). Parameters such as number of needles, seeds, and the dose coverage of the prostate (D90, V150, V200), urethra (D30, D10) and rectum (D5, V100) were compared for the rectilinear and the curvilinear methods. Statistical significance was assessed using two-tailed student's t-test. Results: Reduction of the required number of needles and seeds in curvilinear method were 30.5% (p < 0.001) and 11.8% (p < 0.49), respectively. Dose to the urethra was reduced significantly; D30 reduced by 10.1% (p < 0.01) and D10 reduced by 9.9% (p < 0.02). Reduction in rectum dose D5 was 18.5% (p < 0.03) and V100 was also reduced from 0.93 cc in rectilinear to 0.21 cc in curvilinear (p < 0.001). Also the V150 and V200 coverage of prostate reduced by 18.8% (p < 0.01) and 33.9% (p < 0.001), respectively. Conclusions: Significant improvement in the relevant dosimetric parameters was observed in curvilinear needle approach. Prostate dose homogeneity (V150, V200) improved while urethral dose was reduced, which might potentially result in better treatment outcome. Reduction in rectal dose could potentially reduce rectal toxicity and complications. Reduction in number of needles would minimize edema and thereby could improve postimplant urinary incontinence. This study indicates that the curvilinear implantation approach is dosimetrically superior to conventional rectilinear implantation technique. [ABSTRACT FROM AUTHOR]
Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 74034469
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: A novel curvilinear approach for prostate seed implantation.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Podder%2C+Tarun+K%2E%22&quot;&gt;Podder, Tarun K.&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Dicker%2C+Adam+P%2E%22&quot;&gt;Dicker, Adam P.&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Hutapea%2C+Parsaoran%22&quot;&gt;Hutapea, Parsaoran&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Darvish%2C+Kurosh%22&quot;&gt;Darvish, Kurosh&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Yu%2C+Yan%22&quot;&gt;Yu, Yan&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Medical+Physics%22&quot;&gt;Medical Physics&lt;/searchLink&gt;. Apr2012, Vol. 39 Issue 4, p1887-1892. 6p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Dosimeters%22&quot;&gt;Dosimeters&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Radioisotope+brachytherapy%22&quot;&gt;Radioisotope brachytherapy&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Radiation+doses%22&quot;&gt;Radiation doses&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Prostate+cancer%22&quot;&gt;Prostate cancer&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Rectal+radiography%22&quot;&gt;Rectal radiography&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Parameter+estimation%22&quot;&gt;Parameter estimation&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Health+outcome+assessment%22&quot;&gt;Health outcome assessment&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose: A new technique called &#39;curvilinear approach&#39; for prostate seed implantation has been proposed. The purpose of this study is to evaluate the dosimetric benefit of curvilinear distribution of seeds for low-dose-rate (LDR) prostate brachytherapy. Methods: Twenty LDR prostate brachytherapy cases planned intraoperatively with VariSeed planning system and I-125 seeds were randomly selected as reference rectilinear cases. All the cases were replanned by using curved-needle approach keeping the same individual source strength and the volume receiving 100% of prescribed dose 145 Gy (V100). Parameters such as number of needles, seeds, and the dose coverage of the prostate (D90, V150, V200), urethra (D30, D10) and rectum (D5, V100) were compared for the rectilinear and the curvilinear methods. Statistical significance was assessed using two-tailed student&#39;s t-test. Results: Reduction of the required number of needles and seeds in curvilinear method were 30.5% (p &lt; 0.001) and 11.8% (p &lt; 0.49), respectively. Dose to the urethra was reduced significantly; D30 reduced by 10.1% (p &lt; 0.01) and D10 reduced by 9.9% (p &lt; 0.02). Reduction in rectum dose D5 was 18.5% (p &lt; 0.03) and V100 was also reduced from 0.93 cc in rectilinear to 0.21 cc in curvilinear (p &lt; 0.001). Also the V150 and V200 coverage of prostate reduced by 18.8% (p &lt; 0.01) and 33.9% (p &lt; 0.001), respectively. Conclusions: Significant improvement in the relevant dosimetric parameters was observed in curvilinear needle approach. Prostate dose homogeneity (V150, V200) improved while urethral dose was reduced, which might potentially result in better treatment outcome. Reduction in rectal dose could potentially reduce rectal toxicity and complications. Reduction in number of needles would minimize edema and thereby could improve postimplant urinary incontinence. This study indicates that the curvilinear implantation approach is dosimetrically superior to conventional rectilinear implantation technique. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=74034469
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1118/1.3694110
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 6
        StartPage: 1887
    Subjects:
      – SubjectFull: Dosimeters
        Type: general
      – SubjectFull: Radioisotope brachytherapy
        Type: general
      – SubjectFull: Radiation doses
        Type: general
      – SubjectFull: Prostate cancer
        Type: general
      – SubjectFull: Rectal radiography
        Type: general
      – SubjectFull: Parameter estimation
        Type: general
      – SubjectFull: Health outcome assessment
        Type: general
    Titles:
      – TitleFull: A novel curvilinear approach for prostate seed implantation.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Podder, Tarun K.
      – PersonEntity:
          Name:
            NameFull: Dicker, Adam P.
      – PersonEntity:
          Name:
            NameFull: Hutapea, Parsaoran
      – PersonEntity:
          Name:
            NameFull: Darvish, Kurosh
      – PersonEntity:
          Name:
            NameFull: Yu, Yan
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: Apr2012
              Type: published
              Y: 2012
          Identifiers:
            – Type: issn-print
              Value: 00942405
          Numbering:
            – Type: volume
              Value: 39
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Medical Physics
              Type: main
ResultId 1