Radiation-induced retroelement-mediated genomic instability.
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| Title: | Radiation-induced retroelement-mediated genomic instability. |
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| Authors: | Lee, Ja-Rang1, Kim, Heui-Soo1 khs307@pusan.ac.kr |
| Source: | Biotechnology & Bioprocess Engineering. Jun2012, Vol. 17 Issue 3, p439-445. 7p. |
| Abstract: | Ionizing radiation induces numerous biological events in mammalian cells, including cell death, mutagenesis, and genomic instability via changes in genomic structure, epigenetic regulation, and gene expression. Retroelements can also alter genomic structure based on their ability to mobilize, and their abundance and sequence similarity have been implicated in the pathogenesis of several human diseases. Here, we summarize the current knowledge on the mobilization, genomic rearrangement, epigenetic state, and transcriptional activation of retroelements in response to radiation. We further discuss the potential effects of their activation in radiation-induced genomic instability. [ABSTRACT FROM AUTHOR] |
| Copyright of Biotechnology & Bioprocess Engineering is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 76338385 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Radiation-induced retroelement-mediated genomic instability. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Lee%2C+Ja-Rang%22">Lee, Ja-Rang</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Kim%2C+Heui-Soo%22">Kim, Heui-Soo</searchLink><relatesTo>1</relatesTo><i> khs307@pusan.ac.kr</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Biotechnology+%26+Bioprocess+Engineering%22">Biotechnology & Bioprocess Engineering</searchLink>. Jun2012, Vol. 17 Issue 3, p439-445. 7p. – Name: Abstract Label: Abstract Group: Ab Data: Ionizing radiation induces numerous biological events in mammalian cells, including cell death, mutagenesis, and genomic instability via changes in genomic structure, epigenetic regulation, and gene expression. Retroelements can also alter genomic structure based on their ability to mobilize, and their abundance and sequence similarity have been implicated in the pathogenesis of several human diseases. Here, we summarize the current knowledge on the mobilization, genomic rearrangement, epigenetic state, and transcriptional activation of retroelements in response to radiation. We further discuss the potential effects of their activation in radiation-induced genomic instability. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Biotechnology & Bioprocess Engineering is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s12257-012-0008-3 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 439 Titles: – TitleFull: Radiation-induced retroelement-mediated genomic instability. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lee, Ja-Rang – PersonEntity: Name: NameFull: Kim, Heui-Soo IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2012 Type: published Y: 2012 Identifiers: – Type: issn-print Value: 12268372 Numbering: – Type: volume Value: 17 – Type: issue Value: 3 Titles: – TitleFull: Biotechnology & Bioprocess Engineering Type: main |
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