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Polymerizable nanoparticulate silica-reinforced calcium phosphate bone cement.

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Title: Polymerizable nanoparticulate silica-reinforced calcium phosphate bone cement.
Authors: Hesaraki, Saeed1, Alizadeh, Masoud2, Borhan, Shokoufeh1, Pourbaghi-Masouleh, Milad1
Source: Journal of Biomedical Materials Research, Part B: Applied Biomaterials. Aug2012, Vol. 100B Issue 6, p1627-1635. 9p.
Abstract: Bone cements based on calcium phosphate powder and different concentrations of colloidal silica suspensions were developed. Setting time and washout behavior of the cements were recorded and compared with those of a control group prepared by the same powder phase and distilled water as liquid. The phase composition, compressive strength, and morphology of the cements were determined after incubation and soaking in simulated body fluid. Proliferation of osteoblasts seeded on samples was also determined as a function of time. The results showed that the long setting time, poor compressive strength, and undesirable washout behavior of the cement made with distilled water were considerably improved by adding colloidal silica in a dose-dependent manner. On the basis of XRD and SEM results, both control group and nanosilica-added cements composed of nanosized apatite flakes after 7 days soaking, in addition to tetracalcium phosphate residual for the latter. It was found that the rate of hydraulic reactions that are responsible for conversion of the cement reactants to nanostructured apatite was increased by the presence of colloidal silica. Furthermore, the osteoblasts exhibited better proliferation on nanosilica added cements compared to control one. This study suggests better applied properties for nanosilica-added calcium phosphate cement compared to traditional cements. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 100B: 1627-1635, 2012. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Biomedical Materials Research, Part B: Applied Biomaterials is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Polymerizable nanoparticulate silica-reinforced calcium phosphate bone cement.
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Biomedical+Materials+Research%2C+Part+B%3A+Applied+Biomaterials%22">Journal of Biomedical Materials Research, Part B: Applied Biomaterials</searchLink>. Aug2012, Vol. 100B Issue 6, p1627-1635. 9p.
– Name: Abstract
  Label: Abstract
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  Data: Bone cements based on calcium phosphate powder and different concentrations of colloidal silica suspensions were developed. Setting time and washout behavior of the cements were recorded and compared with those of a control group prepared by the same powder phase and distilled water as liquid. The phase composition, compressive strength, and morphology of the cements were determined after incubation and soaking in simulated body fluid. Proliferation of osteoblasts seeded on samples was also determined as a function of time. The results showed that the long setting time, poor compressive strength, and undesirable washout behavior of the cement made with distilled water were considerably improved by adding colloidal silica in a dose-dependent manner. On the basis of XRD and SEM results, both control group and nanosilica-added cements composed of nanosized apatite flakes after 7 days soaking, in addition to tetracalcium phosphate residual for the latter. It was found that the rate of hydraulic reactions that are responsible for conversion of the cement reactants to nanostructured apatite was increased by the presence of colloidal silica. Furthermore, the osteoblasts exhibited better proliferation on nanosilica added cements compared to control one. This study suggests better applied properties for nanosilica-added calcium phosphate cement compared to traditional cements. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 100B: 1627-1635, 2012. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Journal of Biomedical Materials Research, Part B: Applied Biomaterials is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1002/jbm.b.32731
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      – Code: eng
        Text: English
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      – TitleFull: Polymerizable nanoparticulate silica-reinforced calcium phosphate bone cement.
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            NameFull: Alizadeh, Masoud
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            NameFull: Borhan, Shokoufeh
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            NameFull: Pourbaghi-Masouleh, Milad
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              M: 08
              Text: Aug2012
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              Y: 2012
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              Value: 6
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            – TitleFull: Journal of Biomedical Materials Research, Part B: Applied Biomaterials
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