4D patient dose reconstruction using online measured EPID cine images for lung SBRT treatment validation.
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| Title: | 4D patient dose reconstruction using online measured EPID cine images for lung SBRT treatment validation. |
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| Authors: | Lin, Mu-Han1, Li, Jinsheng1, Wang, Lu1, Koren, Sion1, Fan, Jiajing1, Forkal, Eugene1, Ma, C.-M.1 |
| Source: | Medical Physics. Oct2012, Vol. 39 Issue 10, p5949-5958. 10p. |
| Subjects: | Radiation doses, Image reconstruction, Feasibility studies, Four-dimensional imaging, Image registration, Uncertainty (Information theory), Gamma rays |
| Abstract: | Purpose: This study aims to develop an EPID-guided 4D patient dose reconstruction framework and to investigate its feasibility for lung SBRT treatment validation. Methods: Both the beam apertures and tumor movements were detected based on the continuously acquired EPID images during the treatment. Instead of directly using the transit photon fluence measured by the EPID, this method reconstructed the entrance fluence with the measured beam apertures and the delivered MUs. The entrance fluence distributions were sorted into their corresponding phases based on the detected tumor motion pattern and then accumulated for each phase. Together with the in-room 4DCT taken before every treatment to consider the interfractional-motion, the entrance fluence was then used for the patient dose calculation. Deformable registration was performed to sum up the phase doses for final treatment assessment. The feasibility of using the transit EPID images for entrance fluence reconstruction was evaluated against EPID in-air measurements. The accuracy of 3D- and 4D-dose reconstruction was validated by experiments with a motor-driven cylindrical diode array for six clinical-SBRT plans. Results: The average difference between the measured and reconstructed fluence maps was within 0.16%. The reconstructed 3D-dose showed a less than 1.4% difference for the CAX-dose and at least a 98.3% gamma-passing-rate (2%/2 mm) for the peripheral dose. Distorted dose distributions were observed in the measurement with the moving phantom. The comparison between the measured and the reconstructed 4D-dose without considering temporal information failed the gamma-evaluation for most cases. In contrast, when temporal information was considered, the dose distortion phenomena were successfully represented in the reconstructed dose (97.6%-99.7% gamma-passing rate). Conclusions: The proposed method considered uncertainties of the beam delivery system, the interfractional- and intrafractional-motion, and the interplay effect. The experimental validation demonstrates that this method is practical and accurate for online or offline SBRT patient dose verification. [ABSTRACT FROM AUTHOR] |
| Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Items | – Name: Title Label: Title Group: Ti Data: 4D patient dose reconstruction using online measured EPID cine images for lung SBRT treatment validation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Lin%2C+Mu-Han%22">Lin, Mu-Han</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Li%2C+Jinsheng%22">Li, Jinsheng</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Wang%2C+Lu%22">Wang, Lu</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Koren%2C+Sion%22">Koren, Sion</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Fan%2C+Jiajing%22">Fan, Jiajing</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Forkal%2C+Eugene%22">Forkal, Eugene</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ma%2C+C%2E-M%2E%22">Ma, C.-M.</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Medical+Physics%22">Medical Physics</searchLink>. Oct2012, Vol. 39 Issue 10, p5949-5958. 10p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Radiation+doses%22">Radiation doses</searchLink><br /><searchLink fieldCode="DE" term="%22Image+reconstruction%22">Image reconstruction</searchLink><br /><searchLink fieldCode="DE" term="%22Feasibility+studies%22">Feasibility studies</searchLink><br /><searchLink fieldCode="DE" term="%22Four-dimensional+imaging%22">Four-dimensional imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Image+registration%22">Image registration</searchLink><br /><searchLink fieldCode="DE" term="%22Uncertainty+%28Information+theory%29%22">Uncertainty (Information theory)</searchLink><br /><searchLink fieldCode="DE" term="%22Gamma+rays%22">Gamma rays</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: This study aims to develop an EPID-guided 4D patient dose reconstruction framework and to investigate its feasibility for lung SBRT treatment validation. Methods: Both the beam apertures and tumor movements were detected based on the continuously acquired EPID images during the treatment. Instead of directly using the transit photon fluence measured by the EPID, this method reconstructed the entrance fluence with the measured beam apertures and the delivered MUs. The entrance fluence distributions were sorted into their corresponding phases based on the detected tumor motion pattern and then accumulated for each phase. Together with the in-room 4DCT taken before every treatment to consider the interfractional-motion, the entrance fluence was then used for the patient dose calculation. Deformable registration was performed to sum up the phase doses for final treatment assessment. The feasibility of using the transit EPID images for entrance fluence reconstruction was evaluated against EPID in-air measurements. The accuracy of 3D- and 4D-dose reconstruction was validated by experiments with a motor-driven cylindrical diode array for six clinical-SBRT plans. Results: The average difference between the measured and reconstructed fluence maps was within 0.16%. The reconstructed 3D-dose showed a less than 1.4% difference for the CAX-dose and at least a 98.3% gamma-passing-rate (2%/2 mm) for the peripheral dose. Distorted dose distributions were observed in the measurement with the moving phantom. The comparison between the measured and the reconstructed 4D-dose without considering temporal information failed the gamma-evaluation for most cases. In contrast, when temporal information was considered, the dose distortion phenomena were successfully represented in the reconstructed dose (97.6%-99.7% gamma-passing rate). Conclusions: The proposed method considered uncertainties of the beam delivery system, the interfractional- and intrafractional-motion, and the interplay effect. The experimental validation demonstrates that this method is practical and accurate for online or offline SBRT patient dose verification. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1118/1.4748505 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 5949 Subjects: – SubjectFull: Radiation doses Type: general – SubjectFull: Image reconstruction Type: general – SubjectFull: Feasibility studies Type: general – SubjectFull: Four-dimensional imaging Type: general – SubjectFull: Image registration Type: general – SubjectFull: Uncertainty (Information theory) Type: general – SubjectFull: Gamma rays Type: general Titles: – TitleFull: 4D patient dose reconstruction using online measured EPID cine images for lung SBRT treatment validation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lin, Mu-Han – PersonEntity: Name: NameFull: Li, Jinsheng – PersonEntity: Name: NameFull: Wang, Lu – PersonEntity: Name: NameFull: Koren, Sion – PersonEntity: Name: NameFull: Fan, Jiajing – PersonEntity: Name: NameFull: Forkal, Eugene – PersonEntity: Name: NameFull: Ma, C.-M. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2012 Type: published Y: 2012 Identifiers: – Type: issn-print Value: 00942405 Numbering: – Type: volume Value: 39 – Type: issue Value: 10 Titles: – TitleFull: Medical Physics Type: main |
| ResultId | 1 |
