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An idealized geometry that mimics average infant nasal airway deposition

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Title: An idealized geometry that mimics average infant nasal airway deposition
Authors: Javaheri, E. emad.javaheri@ualberta.ca, Golshahi, L.1, Finlay, W.H. warren.finlay@ualberta.ca
Source: Journal of Aerosol Science. Jan2013, Vol. 55, p137-148. 12p.
Subjects: Airway (Anatomy), Infants, Geometry, Inertial separation (Dust removal), Nose, Aerosols
Abstract: Abstract: An idealized geometry of the infant nasal airways is developed with the goal of mimicking the average inertial filtration of aerosols by the nasal passages. Paramount geometrical features of 10 previously published nasal replicas of infants aged 3–18 months have been considered in creating the idealized version. Simplifications are made to features that do not significantly influence deposition but that make the airway unnecessarily convoluted. A series of overall deposition measurements have been carried out in the idealized replica over a range of particle sizes and breathing patterns. Deposition data for the idealized geometry are compared with those from 10 in vitro subjects. Satisfactory agreement between deposition in the idealized and real geometries suggests that the idealized version can characterize average deposition in the real airways. The present idealized airway could be useful as a reference geometry in experimental and theoretical studies of aerosol delivery through infant nasal airways. [Copyright &y& Elsevier]
Copyright of Journal of Aerosol Science is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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Header DbId: egs
DbLabel: Engineering Source
An: 83933024
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: An idealized geometry that mimics average infant nasal airway deposition
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  Data: <searchLink fieldCode="AR" term="%22Javaheri%2C+E%2E%22">Javaheri, E.</searchLink><i> emad.javaheri@ualberta.ca</i><br /><searchLink fieldCode="AR" term="%22Golshahi%2C+L%2E%22">Golshahi, L.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Finlay%2C+W%2EH%2E%22">Finlay, W.H.</searchLink><i> warren.finlay@ualberta.ca</i>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Aerosol+Science%22">Journal of Aerosol Science</searchLink>. Jan2013, Vol. 55, p137-148. 12p.
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  Data: <searchLink fieldCode="DE" term="%22Airway+%28Anatomy%29%22">Airway (Anatomy)</searchLink><br /><searchLink fieldCode="DE" term="%22Infants%22">Infants</searchLink><br /><searchLink fieldCode="DE" term="%22Geometry%22">Geometry</searchLink><br /><searchLink fieldCode="DE" term="%22Inertial+separation+%28Dust+removal%29%22">Inertial separation (Dust removal)</searchLink><br /><searchLink fieldCode="DE" term="%22Nose%22">Nose</searchLink><br /><searchLink fieldCode="DE" term="%22Aerosols%22">Aerosols</searchLink>
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  Data: Abstract: An idealized geometry of the infant nasal airways is developed with the goal of mimicking the average inertial filtration of aerosols by the nasal passages. Paramount geometrical features of 10 previously published nasal replicas of infants aged 3–18 months have been considered in creating the idealized version. Simplifications are made to features that do not significantly influence deposition but that make the airway unnecessarily convoluted. A series of overall deposition measurements have been carried out in the idealized replica over a range of particle sizes and breathing patterns. Deposition data for the idealized geometry are compared with those from 10 in vitro subjects. Satisfactory agreement between deposition in the idealized and real geometries suggests that the idealized version can characterize average deposition in the real airways. The present idealized airway could be useful as a reference geometry in experimental and theoretical studies of aerosol delivery through infant nasal airways. [Copyright &y& Elsevier]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Journal of Aerosol Science is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1016/j.jaerosci.2012.07.013
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      – Code: eng
        Text: English
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        PageCount: 12
        StartPage: 137
    Subjects:
      – SubjectFull: Airway (Anatomy)
        Type: general
      – SubjectFull: Infants
        Type: general
      – SubjectFull: Geometry
        Type: general
      – SubjectFull: Inertial separation (Dust removal)
        Type: general
      – SubjectFull: Nose
        Type: general
      – SubjectFull: Aerosols
        Type: general
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      – TitleFull: An idealized geometry that mimics average infant nasal airway deposition
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            NameFull: Golshahi, L.
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            NameFull: Finlay, W.H.
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              M: 01
              Text: Jan2013
              Type: published
              Y: 2013
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              Value: 55
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