Regional effects of magnetization dispersion on quantitative perfusion imaging for pulsed and continuous arterial spin labeling.
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| Title: | Regional effects of magnetization dispersion on quantitative perfusion imaging for pulsed and continuous arterial spin labeling. |
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| Authors: | Çavuşoğlu, Mustafa1,2 mustafa.cavusoglu@tuebingEN.mpg.de, Pohmann, Rolf1, Burger, Harold Christopher3, Uludağ, Kâmil4 |
| Source: | Magnetic Resonance in Medicine. Feb2013, Vol. 69 Issue 2, p524-530. 7p. |
| Abstract: | Most experiments assume a global transit delay time with blood flowing from the tagging region to the imaging slice in plug flow without any dispersion of the magnetization. However, because of cardiac pulsation, nonuniform cross-sectional flow profile, and complex vessel networks, the transit delay time is not a single value but follows a distribution. In this study, we explored the regional effects of magnetization dispersion on quantitative perfusion imaging for varying transit times within a very large interval from the direct comparison of pulsed, pseudo-continuous, and dual-coil continuous arterial spin labeling encoding schemes. Longer distances between tagging and imaging region typically used for continuous tagging schemes enhance the regional bias on the quantitative cerebral blood flow measurement causing an underestimation up to 37% when plug flow is assumed as in the standard model. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR] |
| Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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