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Three-component synthesis of poly-substituted tetrahydroindoles through p-TsOH promoted alkoxylation.

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Title: Three-component synthesis of poly-substituted tetrahydroindoles through p-TsOH promoted alkoxylation.
Authors: Shi, Qing-Qing1, Fu, Li-Ping1, Shi, Yu1, Ding, Hua-Qin1, Luo, Jing-Hua1, Jiang, Bo1 jiangchem@jsnu.edu.cn, Tu, Shu-Jiang1 laotu@jsnu.edu.cn
Source: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jun2013, Vol. 54 Issue 24, p3176-3179. 4p.
Subjects: Substitution reactions, Indole compounds, Organic synthesis, Alkoxylation, Chemical derivatives, Chemical reactions
Abstract: Abstract: Concise and efficient three-component domino reactions to highly substituted tetrahydroindole derivatives promoted by p-TsOH have been developed under microwave irradiation condition. The direct C3-alkoxylation of indole framework was achieved in a one-pot operation. The reaction proceeds at fast rates and can be finished within 30min, which makes workup convenient to give good chemical yields. [Copyright &y& Elsevier]
Copyright of Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 89120808
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Three-component synthesis of poly-substituted tetrahydroindoles through p-TsOH promoted alkoxylation.
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  Data: <searchLink fieldCode="AR" term="%22Shi%2C+Qing-Qing%22">Shi, Qing-Qing</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Fu%2C+Li-Ping%22">Fu, Li-Ping</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Shi%2C+Yu%22">Shi, Yu</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ding%2C+Hua-Qin%22">Ding, Hua-Qin</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Luo%2C+Jing-Hua%22">Luo, Jing-Hua</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Jiang%2C+Bo%22">Jiang, Bo</searchLink><relatesTo>1</relatesTo><i> jiangchem@jsnu.edu.cn</i><br /><searchLink fieldCode="AR" term="%22Tu%2C+Shu-Jiang%22">Tu, Shu-Jiang</searchLink><relatesTo>1</relatesTo><i> laotu@jsnu.edu.cn</i>
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  Data: <searchLink fieldCode="JN" term="%22Tetrahedron+Letters%3A+International+Organ+for+the+Rapid+Publication+of+Preliminary+Communications+in+Organic+Chemistry%22">Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry</searchLink>. Jun2013, Vol. 54 Issue 24, p3176-3179. 4p.
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  Data: <searchLink fieldCode="DE" term="%22Substitution+reactions%22">Substitution reactions</searchLink><br /><searchLink fieldCode="DE" term="%22Indole+compounds%22">Indole compounds</searchLink><br /><searchLink fieldCode="DE" term="%22Organic+synthesis%22">Organic synthesis</searchLink><br /><searchLink fieldCode="DE" term="%22Alkoxylation%22">Alkoxylation</searchLink><br /><searchLink fieldCode="DE" term="%22Chemical+derivatives%22">Chemical derivatives</searchLink><br /><searchLink fieldCode="DE" term="%22Chemical+reactions%22">Chemical reactions</searchLink>
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  Data: Abstract: Concise and efficient three-component domino reactions to highly substituted tetrahydroindole derivatives promoted by p-TsOH have been developed under microwave irradiation condition. The direct C3-alkoxylation of indole framework was achieved in a one-pot operation. The reaction proceeds at fast rates and can be finished within 30min, which makes workup convenient to give good chemical yields. [Copyright &y& Elsevier]
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  Data: <i>Copyright of Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: Jun2013
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