Nardokanshone A, a new type of sesquieterpenoid–chalcone hybrid from Nardostachys chinensis.

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Title: Nardokanshone A, a new type of sesquieterpenoid–chalcone hybrid from Nardostachys chinensis.
Authors: Wang, Peng-Cheng1,2, Ran, Xin-Hui1, Luo, Huai-Rong2, Zheng, Yi-Min1, Liu, Yu-Qing2, Hu, Jiang-Miao2 hujiangmiao@mail.kib.ac.cn, Zhou, Jun2 zhoujun3264@yahoo.com.cn
Source: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Aug2013, Vol. 54 Issue 33, p4365-4368. 4p.
Subjects: Chalcones, Dihydrofurans, Spectrum analysis, Quantum chemistry, Density functional theory, Flavones
Abstract: Abstract: Nardokanshone A (1), a new type of sesquieterpenoid–chalcone hybird, with a 2,3-dihydrofuran ring fusing an aristolane-type sesquiterpenoid and a chalcone, along with its possible bioprecursor, kanshone C (2), together with four known flavones were isolated from Nardostachys chinensis. Their structures were elucidated by spectroscopic methods, and the absolute configuration of 1 was determined by quantum chemical DFT calculations. The possible biosynthetic pathway of 1 was also proposed. [Copyright &y& Elsevier]
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Abstract:Abstract: Nardokanshone A (1), a new type of sesquieterpenoid–chalcone hybird, with a 2,3-dihydrofuran ring fusing an aristolane-type sesquiterpenoid and a chalcone, along with its possible bioprecursor, kanshone C (2), together with four known flavones were isolated from Nardostachys chinensis. Their structures were elucidated by spectroscopic methods, and the absolute configuration of 1 was determined by quantum chemical DFT calculations. The possible biosynthetic pathway of 1 was also proposed. [Copyright &y& Elsevier]
ISSN:00404039
DOI:10.1016/j.tetlet.2013.05.127