On the Nature of DNA Hyperchromic Effect.
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| Title: | On the Nature of DNA Hyperchromic Effect. |
|---|---|
| Authors: | D’Abramo, Marco1, Castellazzi, Chiara Lara1, Orozco, Modesto1, Amadei, Andrea1 |
| Source: | Journal of Physical Chemistry B. Jul2013, Vol. 117 Issue 29, p8697-8704. 8p. |
| Subjects: | Hyperchromic effect, DNA denaturation, Molecular interactions, Molecular physics, Ultraviolet radiation, Delocalization energy |
| Abstract: | A combined theoretical–experimentalstudy of the hyperchromiceffect as occurring in the denaturation of a double stranded polyA-polyTis presented. Our theoretical/computational procedure allows us toreproduce the essential features of the experimental spectra and tocharacterize those molecular interactions responsible for the changesin the UV absorbance. We found that although excitonic intrastrandinteractions strongly affect the absorbance, they are almost fullymaintained in the single-stranded DNA. Our data indicate that hyperchromiceffect originates from the higher delocalization of the excitonicstates in the denaturated DNA with respect to the double-strandedconformation. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Physical Chemistry B is the property of American Chemical Society and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 89431212 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: On the Nature of DNA Hyperchromic Effect. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22D’Abramo%2C+Marco%22">D’Abramo, Marco</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Castellazzi%2C+Chiara+Lara%22">Castellazzi, Chiara Lara</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Orozco%2C+Modesto%22">Orozco, Modesto</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Amadei%2C+Andrea%22">Amadei, Andrea</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Physical+Chemistry+B%22">Journal of Physical Chemistry B</searchLink>. Jul2013, Vol. 117 Issue 29, p8697-8704. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Hyperchromic+effect%22">Hyperchromic effect</searchLink><br /><searchLink fieldCode="DE" term="%22DNA+denaturation%22">DNA denaturation</searchLink><br /><searchLink fieldCode="DE" term="%22Molecular+interactions%22">Molecular interactions</searchLink><br /><searchLink fieldCode="DE" term="%22Molecular+physics%22">Molecular physics</searchLink><br /><searchLink fieldCode="DE" term="%22Ultraviolet+radiation%22">Ultraviolet radiation</searchLink><br /><searchLink fieldCode="DE" term="%22Delocalization+energy%22">Delocalization energy</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: A combined theoretical–experimentalstudy of the hyperchromiceffect as occurring in the denaturation of a double stranded polyA-polyTis presented. Our theoretical/computational procedure allows us toreproduce the essential features of the experimental spectra and tocharacterize those molecular interactions responsible for the changesin the UV absorbance. We found that although excitonic intrastrandinteractions strongly affect the absorbance, they are almost fullymaintained in the single-stranded DNA. Our data indicate that hyperchromiceffect originates from the higher delocalization of the excitonicstates in the denaturated DNA with respect to the double-strandedconformation. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Physical Chemistry B is the property of American Chemical Society and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/jp403369k Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 8697 Subjects: – SubjectFull: Hyperchromic effect Type: general – SubjectFull: DNA denaturation Type: general – SubjectFull: Molecular interactions Type: general – SubjectFull: Molecular physics Type: general – SubjectFull: Ultraviolet radiation Type: general – SubjectFull: Delocalization energy Type: general Titles: – TitleFull: On the Nature of DNA Hyperchromic Effect. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: D’Abramo, Marco – PersonEntity: Name: NameFull: Castellazzi, Chiara Lara – PersonEntity: Name: NameFull: Orozco, Modesto – PersonEntity: Name: NameFull: Amadei, Andrea IsPartOfRelationships: – BibEntity: Dates: – D: 25 M: 07 Text: Jul2013 Type: published Y: 2013 Identifiers: – Type: issn-print Value: 15206106 Numbering: – Type: volume Value: 117 – Type: issue Value: 29 Titles: – TitleFull: Journal of Physical Chemistry B Type: main |
| ResultId | 1 |
